{"id":17480,"date":"2014-09-10T23:19:11","date_gmt":"2014-09-10T21:19:11","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=17480"},"modified":"2014-09-10T23:19:11","modified_gmt":"2014-09-10T21:19:11","slug":"bludiste-prenesene-do-pocitacove-hry-ma-odhalit-schizofrenii","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=17480","title":{"rendered":"Bludi\u0161t\u011b p\u0159enesen\u00e9 do po\u010d\u00edta\u010dov\u00e9 hry m\u00e1 odhalit schizofrenii"},"content":{"rendered":"

Bludi\u0161t\u011b pro laboratorn\u00ed potkany p\u0159enesen\u00e9 do po\u010d\u00edta\u010dov\u00e9 hry m\u00e1 podle Ivety Fajnerov\u00e9 z N\u00e1rodn\u00edho \u00fastavu du\u0161evn\u00edho zdrav\u00ed pomoci odhalit prvn\u00ed projevy schizofrenie a v budoucnu i efektivn\u011bji testovat nov\u00e9 psychiatrick\u00e9 l\u00e9ky.<\/strong> <\/p>\n

V\u011bdkyn\u011b \u0159ekla, \u017ee ve studii ov\u011b\u0159uj\u00ed u\u017eite\u010dnost zv\u00ed\u0159ec\u00edho modelu srovn\u00e1n\u00edm jeho v\u00fdsledk\u016f s testy pacient\u016f trp\u00edc\u00edch schizofreni\u00ed a zdrav\u00fdch dobrovoln\u00edk\u016f. Studie z\u00edskala ocen\u011bn\u00ed Neuropsychofarmakologick\u00e9 spole\u010dnosti za rok 2013 a publikoval ji \u010dasopis Frontiers in Behavioural Neuroscience.<\/p>\n

„Potkana se nem\u016f\u017eeme zeptat, zda sly\u0161\u00ed hlasy, nebo pro\u017e\u00edv\u00e1 vkl\u00e1d\u00e1n\u00ed my\u0161lenek. Dok\u00e1\u017eeme ale zjistit jeho pocit ohro\u017een\u00ed, kter\u00fd pat\u0159\u00ed k projev\u016fm bludn\u00fdch p\u0159edstav u schizofrenie, a to sledov\u00e1n\u00edm zm\u011bn v jeho chov\u00e1n\u00ed – b\u00e1zliv\u00e9 nebo odv\u00e1\u017en\u00e9 prohled\u00e1v\u00e1n\u00ed nov\u00e9ho prostoru a reakci na stres,“ \u0159ekla s t\u00edm, \u017ee podobn\u011b lze sledovat i naru\u0161en\u00ed kognitivn\u00edch funkc\u00ed, kter\u00e9 je \u010dast\u00fdm projevem u psychiatrick\u00fdch onemocn\u011bn\u00ed.<\/p>\n

Kognitivn\u00ed funkce jsou spojeny s pozornost\u00ed a soust\u0159ed\u011bn\u00edm, pam\u011bt\u00ed, logick\u00fdm my\u0161len\u00edm a pl\u00e1nov\u00e1n\u00edm. P\u0159i schizofrenii jsou naru\u0161eny, co\u017e je tak\u00e9 vod\u00edtko pro stanoven\u00ed diagn\u00f3zy.<\/p>\n

U zv\u00ed\u0159at se tyto funkce testuj\u00ed pomoc\u00ed prostorov\u00fdch \u00faloh: Morrisonova vodn\u00edho bludi\u0161t\u011b a rotuj\u00edc\u00ed ar\u00e9ny. Ve vodn\u00edm bludi\u0161ti potkan plave k zapamatovan\u00e9mu m\u00edstu pod hladinou a je pro n\u011bj odm\u011bnou, proto\u017ee mu umo\u017en\u00ed z vody vyl\u00e9zt. U rotuj\u00edc\u00ed ar\u00e9ny se vyh\u00fdb\u00e1 zak\u00e1zan\u00e9 oblasti. Zv\u00ed\u0159e si ale mus\u00ed vytvo\u0159it a zapamatovat jakousi mapu prostoru. Testy proto slou\u017e\u00ed k vy\u0161et\u0159en\u00ed schopnosti u\u010den\u00ed a pam\u011bti.<\/p>\n

Analogiemi zv\u00ed\u0159ec\u00edch test\u016f jsou virtu\u00e1ln\u00ed testy vytvo\u0159en\u00e9 ve spolupr\u00e1ci s laborato\u0159\u00ed neurofyziologie pam\u011bti Fyziologick\u00e9ho \u00fastavu Akademie v\u011bd a matematicko-fyzik\u00e1ln\u00ed fakultou Univerzity Karlovy.<\/p>\n

Ve studii u\u017e\u00edvaj\u00ed v\u011bdci tyto testy u pacient\u016f po prvn\u00edm projevu psych\u00f3zy a u zdrav\u00fdch dobrovoln\u00edk\u016f. „P\u0159edb\u011b\u017en\u00e9 v\u00fdsledky ukazuj\u00ed, \u017ee v prvn\u00edm z test\u016f m\u00e1 skupina pacient\u016f pr\u016fm\u011brn\u011b o 20 procent hor\u0161\u00ed v\u00fdsledky a v rotuj\u00edc\u00ed ar\u00e9n\u011b je v\u00fdsledek dokonce dvakr\u00e1t hor\u0161\u00ed,“ uvedla v\u011bdkyn\u011b.<\/p>\n

V\u00fdzkum podle n\u00ed tak\u00e9 uk\u00e1zal, \u017ee v\u011bt\u0161ina pacient\u016f ji\u017e po prvn\u00ed projevu nemoci d\u011bl\u00e1 v\u00edc chyb a pot\u0159ebuje del\u0161\u00ed \u010das k nalezen\u00ed c\u00edle. Efektivita navigace je ni\u017e\u0161\u00ed ne\u017e u zdrav\u00fdch lid\u00ed, co\u017e odpov\u00edd\u00e1 i zji\u0161t\u011bn\u00fdm zm\u011bn\u00e1m v chov\u00e1n\u00ed testovan\u00fdch zv\u00ed\u0159at. Studie d\u00e1le pokra\u010duje, p\u0159ihl\u00e1sit se mohou dal\u0161\u00ed zdrav\u00ed dobrovoln\u00edci.<\/p>\n

ilustra\u010dn\u00ed foto: Flickr.com<\/p>\n","protected":false},"excerpt":{"rendered":"

Bludi\u0161t\u011b pro laboratorn\u00ed potkany p\u0159enesen\u00e9 do po\u010d\u00edta\u010dov\u00e9 hry m\u00e1 podle Ivety Fajnerov\u00e9 z N\u00e1rodn\u00edho \u00fastavu du\u0161evn\u00edho zdrav\u00ed pomoci odhalit prvn\u00ed projevy schizofrenie a v budoucnu […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":14654,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-17480","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17480","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17480"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17480\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/14654"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17480"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17480"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17480"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}