{"id":17518,"date":"2014-09-14T23:43:57","date_gmt":"2014-09-14T21:43:57","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=17518"},"modified":"2014-09-14T23:51:18","modified_gmt":"2014-09-14T21:51:18","slug":"japonci-provedli-na-svete-prvni-transplantaci-sitnice-z-kmenovych-bunek","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=17518","title":{"rendered":"Japonci provedli na sv\u011bt\u011b prvn\u00ed transplantaci s\u00edtnice z kmenov\u00fdch bun\u011bk"},"content":{"rendered":"

V Japonsku byla v p\u00e1tek provedena ve sv\u011bt\u011b<\/span> prvn\u00ed\u00a0<\/span>transplantace<\/span> s\u00edtnice<\/span> vytvo\u0159en\u00e9 z indukovan\u00fdch<\/span> kmenov\u00fdch bun\u011bk. Pacientka, j\u00ed\u017e je p\u0159es 70 let, \u0159\u00edk\u00e1, \u017ee u\u017e nyn\u00ed vid\u00ed jasn\u011bji. Informoval o tom anglicky psan\u00fd list Japan Times.\u00a0<\/span> <\/strong><\/p>\n

Pacientce byla \u010d\u00e1st um\u011ble vytvo\u0159en\u00e9 s\u00edtnice <\/span>voperov\u00e1na do<\/span> jej\u00edho<\/span> prav\u00e9ho oka<\/span>, kter\u00e9 bylo t\u011b\u017ece posti\u017eeno v\u011bkem podm\u00edn\u011bnou degenerac\u00ed makuly s\u00edtnice.<\/p>\n

„T<\/span>ransplantace snad\u00a0p\u0159inese<\/span> efekt<\/span>, ale je p\u0159\u00edli\u0161 brzy na to<\/span> \u0159\u00edct, v jak\u00e9 m\u00ed\u0159e,“<\/span> \u0159ekl na tiskov\u00e9 konferenci Yasuo Kurimoto<\/span> z \u00dastavu<\/span> biomedic\u00ednsk\u00e9ho<\/span> v\u00fdzkumu a<\/span> inovac\u00ed p\u0159i\u00a0<\/span> nemocnici<\/span> v<\/span> m\u011bst\u011b Kobe (<\/span>Riken institut).<\/p>\n

Operace<\/span> byla provedena<\/span> s c\u00edlem l\u00e9\u010dby<\/span> exsudativn\u00ed<\/span> v\u011bkem podm\u00edn\u011bn\u00e9 makul\u00e1rn\u00ed<\/span> degenerace<\/span>, kter\u00e1 zp\u016fsobuje abnorm\u00e1ln\u00ed<\/span> tvorbu<\/span> krevn\u00edch c\u00e9v<\/span> v<\/span> s\u00edtnici<\/span> a m\u016f\u017ee v\u00e9st k<\/span> \u00fapln\u00e9 ztr\u00e1t\u011b<\/span> zraku.<\/span><\/p>\n

P\u0159i<\/span> poopera\u010dn\u00edm vy\u0161et\u0159en\u00ed<\/span> pacientky v sobotu bylo zji\u0161t\u011bno, \u017ee implantovan\u00fd\u00a0<\/span>list nov\u00e9 s\u00edtnice<\/span> byl um\u00edst\u011bn<\/span> ve spr\u00e1vn\u00e9 poloze<\/span> a<\/span> bez<\/span> zn\u00e1mek krv\u00e1cen\u00ed nebo<\/span> jin\u00fdch komplikac\u00ed<\/span>.<\/span><\/p>\n

Pacientka m\u011bla\u00a0<\/span>p\u0159i sn\u00eddani<\/span> dobrou n\u00e1ladu a \u0159ekla, \u017ee<\/span> jasn\u011b vid\u00ed\u00a0<\/span>b\u00edlou<\/span> barvu<\/span> pl\u00e1\u0161t\u011b zdravotn\u00edka.<\/p>\n

Z\u00e1krok sou\u010dasn\u011b zbavil pacientku\u00a0abnorm\u00e1ln\u00edch<\/span> c\u00e9v<\/span> na s\u00edtnici. „To <\/span>by m\u011blo pomoci<\/span> pacientce<\/span> l\u00e9pe<\/span> p\u0159ij\u00edmat<\/span> sv\u011btlo v<\/span> oku<\/span>, \u0159ekl<\/span> Kurimoto s t\u00edm, \u017ee t<\/span>o obvykle trv\u00e1<\/span> \u0161est m\u011bs\u00edc\u016f a\u017e<\/span> jeden rok ne\u017e\u00a0<\/span>pacient<\/span> dos\u00e1hne<\/span> maxim\u00e1ln\u00edch<\/span> zrakov\u00fdch schopnost\u00ed\u00a0<\/span>po operaci<\/span>.<\/span><\/p>\n

O\u010dek\u00e1v\u00e1 se, \u017ee<\/span> pacientka opust\u00ed nemocnici<\/span> asi<\/span> do t\u00fddne<\/span>, pokud jej\u00ed stav<\/span> bude nad\u00e1le<\/span> dobr\u00fd<\/span>.<\/p>\n

L\u00e9ka\u0159i budou nad\u00e1le pacientku sledovat a zji\u0161\u0165ovat, zda v nov\u00e9 s\u00edtnici nap\u0159\u00edklad nevznikaj\u00ed rakovinn\u00e9 bu\u0148ky nebo nedoch\u00e1z\u00ed k jin\u00fdm chorobn\u00fdm zm\u011bn\u00e1m. Zpr\u00e1vu o kone\u010dn\u00e9m v\u00fdsledku operace hodlaj\u00ed publikovat a\u017e po roce sledov\u00e1n\u00ed.\u00a0 <\/span><\/p>\n

Podle\u00a0<\/span>pl\u00e1nu<\/span> se<\/span> transplantace<\/span> provede na\u00a0<\/span>celkem \u0161esti<\/span> pacientech, kte\u0159\u00ed trp\u00ed<\/span> stejnou nemoc\u00ed<\/span> o\u010d\u00ed. \u017d<\/span>ena, kter\u00e1<\/span> podstoupila<\/span> operaci<\/span> v p\u00e1tek, byla prvn\u00ed z nich.
\n<\/span><\/p>\n

V\u00fdzkumn\u00edk<\/span> Riken<\/span> institutu Masayo<\/span> Takahashi<\/span>, kter\u00fd stoj\u00ed v \u010dele<\/span> projektu<\/span>, \u0159ekl, \u017ee projekt m\u016f\u017ee b\u00fdt zdr\u017een nutnost\u00ed zm\u011bny z\u00e1kona<\/span>, ale<\/span> t\u00fdm je p\u0159ipraven<\/span> rychle<\/span>\u00a0s projektem postupovat.\u00a0<\/span><\/p>\n

T\u00fdm vytvo\u0159il v laboratorn\u00edch podm\u00ednk\u00e1ch pl\u00e1t s\u00edtnice z vlastn\u00edch kmenov\u00fdch bun\u011bk pacientky. \u0160lo o takzvan\u00e9 indukovan\u00e9 pluripotentn\u00ed bu\u0148ky, kter\u00e9 byly vytvo\u0159eny c\u00edlenou modifikac\u00ed ji\u017e diferencovan\u00fdch bun\u011bk t\u011bla. Indukovan\u00e9 pluripotentn\u00ed bu\u0148ky se sv\u00fdmi vlastnostmi nejv\u00edce bl\u00ed\u017e\u00ed embryon\u00e1ln\u00edm kmenov\u00fdm bu\u0148k\u00e1m a maj\u00ed \u0161irok\u00fd diferencia\u010dn\u00ed potenci\u00e1l.<\/p>\n","protected":false},"excerpt":{"rendered":"

V Japonsku byla v p\u00e1tek provedena ve sv\u011bt\u011b prvn\u00ed\u00a0transplantace s\u00edtnice vytvo\u0159en\u00e9 z indukovan\u00fdch kmenov\u00fdch bun\u011bk. Pacientka, j\u00ed\u017e je p\u0159es 70 let, \u0159\u00edk\u00e1, \u017ee u\u017e nyn\u00ed […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":14584,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-17518","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17518","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17518"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17518\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/14584"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17518"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17518"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17518"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}