{"id":17697,"date":"2014-10-02T07:51:40","date_gmt":"2014-10-02T05:51:40","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=17697"},"modified":"2014-10-02T07:51:58","modified_gmt":"2014-10-02T05:51:58","slug":"u-naladovych-zen-je-pry-vetsi-riziko-onemocneni-alzheimerem","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=17697","title":{"rendered":"U n\u00e1ladov\u00fdch \u017een je v\u011bt\u0161\u00ed riziko onemocn\u011bn\u00ed Alzheimerem"},"content":{"rendered":"

N\u00e1ladovost, z\u00e1vist, \u00fazkost a jin\u00e9 neurotick\u00e9 projevy u \u017een zvy\u0161uj\u00ed riziko onemocn\u011bn\u00ed Alzheimerovou chorobou a jin\u00fdmi druhy demence. Zjistili to \u0161v\u00e9d\u0161t\u00ed v\u011bdci ve studii, kter\u00e1 byla zve\u0159ejn\u011bna v internetov\u00e9m vyd\u00e1n\u00ed odborn\u00e9ho \u010dasopisu Neurology. <\/strong><\/p>\n

T\u00fdm kolem \u0161v\u00e9dsk\u00e9 neurolo\u017eky Leny Johanssonov\u00e9 z G\u00f6teborsk\u00e9 univerzity sledoval po dobu 38 let 800 \u017een. S pomoc\u00ed r\u016fzn\u00fdch ot\u00e1zek u nich v\u011bdci zji\u0161\u0165ovali m\u00edru neurotismu a rovn\u011b\u017e jejich introverzi \u010di extroverzi.<\/p>\n

Neurotismus, neboli du\u0161evn\u00ed nerovnov\u00e1ha, se vyzna\u010duje z\u00e1vist\u00ed, n\u00e1ladovost\u00ed, podr\u00e1\u017ed\u011bnost\u00ed \u010di n\u00e1chylnost\u00ed ke stresu. Neuroti\u010dt\u00ed lid\u00e9 jsou tak\u00e9 n\u00e1chyln\u011bj\u0161\u00ed k z\u00e1chvat\u016fm vzteku, \u00fazkosti a depres\u00edm.<\/p>\n

Dohromady ze vzorku onemocn\u011blo 153 \u017een demenc\u00ed, z toho 104 Alzheimerovou chorobou. V\u011bdci zjistili, \u017ee \u017eeny, kter\u00e9 se v testech uk\u00e1zaly jako velmi neurotick\u00e9, onemocn\u011bly demenc\u00ed dvakr\u00e1t \u010dast\u011bji ne\u017e \u017eeny, kter\u00e9 vykazovaly n\u00edzk\u00e9 hodnoty du\u0161evn\u00ed nerovnov\u00e1hy. Jej\u00ed m\u00edra v\u0161ak z\u00e1visela tak\u00e9 na tom, zda \u017eeny byly del\u0161\u00ed dobu vystaveny stresu.<\/p>\n

Introverze \u010di extroverze samy o sob\u011b riziko demence zjevn\u011b p\u0159\u00edli\u0161 neovliv\u0148uj\u00ed. \u017deny, kter\u00e9 m\u011bly vysok\u00e9 hodnoty du\u0161evn\u00ed nerovnov\u00e1hy a z\u00e1rove\u0148 byly introvertn\u00ed, v\u0161ak podle studie byly vystaveny nejv\u011bt\u0161\u00edmu riziku Alzheimerovy choroby. Z 63 t\u011bchto \u017een onemocn\u011blo 16. Naopak z 64 m\u00e1lo neurotick\u00fdch extrovertek postihla Alzheimerova choroba osm.<\/p>\n

V\u00fdsledky maj\u00ed podle v\u011bdc\u016f n\u011bkolik mo\u017en\u00fdch vysv\u011btlen\u00ed. M\u00e9n\u011b neuroti\u010dt\u00ed lid\u00e9 \u010dasto vedou zdrav\u011bj\u0161\u00ed \u017eivot. Druh\u00fdm mo\u017en\u00fdm vysv\u011btlen\u00edm je skute\u010dnost, \u017ee jak neurotismus, tak stres jsou odpov\u011bdn\u00e9 za zm\u011bny v hipokampu, co\u017e je \u010d\u00e1st mozku, kter\u00e1 ovliv\u0148uje u\u010den\u00ed nebo kr\u00e1tkodobou pam\u011b\u0165. Neurotismus nav\u00edc souvis\u00ed s v\u00fdskytem takzvan\u00fdch neurofibril\u00e1rn\u00edch uzl\u00ed\u010dk\u016f, kter\u00e9 jsou typick\u00e9 p\u0159i struktur\u00e1ln\u00edch zm\u011bn\u00e1ch v mozku posti\u017een\u00e9m Alzheimerovou chorobou.<\/p>\n

Souvislost mezi du\u0161evn\u00ed nevyrovnanost\u00ed, stresem a demenc\u00ed nazna\u010dovaly i d\u0159\u00edv\u011bj\u0161\u00ed pozorov\u00e1n\u00ed. P\u0159i stresu se v\u00edce aktivuje imunitn\u00ed syst\u00e9m, co\u017e vede k arterioskler\u00f3ze, a ta zase p\u0159isp\u00edv\u00e1 k oslaben\u00ed kognitivn\u00edch schopnost\u00ed, vysv\u011btlil n\u011bmeck\u00fd neurolog Stefan Knecht, jeho\u017e citovala agentury DPA.<\/p>\n

V\u011bdci ze stockholmsk\u00e9 univerzity Institut Karolinska u\u017e v roce 2009 pozorovali, \u017ee osoby, kter\u00e9 se ozna\u010dovaly za klidn\u00e9, uvoln\u011bn\u00e9 a nepodl\u00e9haj\u00edc\u00ed stresu, postihovala demence o 50 procent m\u00e9n\u011b \u010dasto ne\u017e ostatn\u00ed.<\/p>\n

ilustra\u010dn\u00ed foto: PhotoRack.net<\/p>\n","protected":false},"excerpt":{"rendered":"

N\u00e1ladovost, z\u00e1vist, \u00fazkost a jin\u00e9 neurotick\u00e9 projevy u \u017een zvy\u0161uj\u00ed riziko onemocn\u011bn\u00ed Alzheimerovou chorobou a jin\u00fdmi druhy demence. Zjistili to \u0161v\u00e9d\u0161t\u00ed v\u011bdci ve studii, kter\u00e1 […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":15727,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-17697","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17697"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/17697\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/15727"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17697"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=17697"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=17697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}