{"id":18032,"date":"2014-10-23T08:27:27","date_gmt":"2014-10-23T06:27:27","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=18032"},"modified":"2014-10-23T08:28:16","modified_gmt":"2014-10-23T06:28:16","slug":"po-transplantaci-cichovych-bunek-muze-opet-chodit","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=18032","title":{"rendered":"Po transplantaci \u010dichov\u00fdch bun\u011bk m\u016f\u017ee op\u011bt chodit"},"content":{"rendered":"

Pol\u00e1k Darek Fidyka, kter\u00fd byl po \u00fatoku no\u017eem v roce 2010 od hrudi dol\u016f paralyzov\u00e1n, m\u016f\u017ee po unik\u00e1tn\u00ed transplantaci \u010dichov\u00fdch bun\u011bk do posti\u017een\u00e9 oblasti m\u00edchy znovu chodit. <\/strong><\/p>\n

Operaci, kter\u00e1 je u \u010dlov\u011bka podle v\u0161eho prvn\u00ed sv\u00e9ho druhu, provedli v Polsku pol\u0161t\u00ed a brit\u0161t\u00ed v\u011bdci. Fidyka se p\u0159i ch\u016fzi mus\u00ed prozat\u00edm spol\u00e9hat na podp\u011brnou konstrukci a tak\u00e9 se rychle unav\u00ed, podle stanice BBC je ale p\u0159esv\u011bd\u010den, \u017ee jednou se bude pohybovat op\u011bt zcela nez\u00e1visle. <\/strong><\/p>\n

ilustra\u010dn\u00ed foto<\/p>\n

„Zapsal jste se do historie. Pro m\u011b je toto mnohem \u00fachvatn\u011bj\u0161\u00ed ne\u017e \u010dlov\u011bk na M\u011bs\u00edci,“ \u0159ekl Fidykovi Geoff Raisman, kter\u00fd p\u0159i operaci a n\u00e1sledn\u00e9 rekonvalescenci vedl britsk\u00fd t\u00fdm v\u011bdc\u016f. Podrobnosti o p\u0159elomov\u00e9 operaci odborn\u00edci zve\u0159ejnili v magaz\u00ednu Cell Transplantation.<\/p>\n

\u010cty\u0159icetilet\u00fd b\u00fdval\u00fd hasi\u010d Fidyka byl v roce 2010 n\u011bkolikr\u00e1t bodnut do zad. \u010cepel no\u017ee p\u0159i \u00fatoku sice pro\u0159\u00edzla m\u00edchu, zcela ji v\u0161ak nep\u0159eru\u0161ila. Fidyk\u016fv stav se ale ani po dvou letech intenzivn\u00ed fyzioterapie nijak nezlep\u0161oval, proto l\u00e9ka\u0159i p\u0159istoupili k experiment\u00e1ln\u00ed transplantaci \u010dichov\u00fdch bun\u011bk. Do nich v\u011bdci d\u00edky jejich regenera\u010dn\u00edm vlastnostem a schopnostem navazovat kontakty s neurony dlouhodob\u011b vkl\u00e1daj\u00ed velk\u00e9 nad\u011bje.<\/p>\n

Transplantace byla rozd\u011blena do dvou f\u00e1z\u00ed. P\u0159i prvn\u00ed operaci l\u00e9ka\u0159i pacientovi odebrali jeden z jeho dvou \u010dichov\u00fdch bulb\u016f, co\u017e je \u010d\u00e1st mozku, do kter\u00e9 p\u0159ich\u00e1zej\u00ed informace z \u010dichov\u00fdch org\u00e1n\u016f. Bu\u0148ky z toho bulbu, ozna\u010dovan\u00e9ho n\u011bkdy tak\u00e9 jako \u010dichov\u00fd kyj, pak nechali v kultiva\u010dn\u00edm prost\u0159ed\u00ed r\u016fst.<\/p>\n

O dva t\u00fddny pozd\u011bji p\u0159istoupili k druh\u00e9 operaci, kdy tyto \u010dichov\u00e9 bu\u0148ky (v angli\u010dtin\u011b ozna\u010dovan\u00e9 zkratkou OEC) transplantovali do posti\u017een\u00e9 m\u00ed\u0161n\u00ed oblasti. Celkem byla provedena asi stovka mikroinjekt\u00e1\u017e\u00ed nad a pod m\u00edsto zran\u011bn\u00ed. Pacientovi vedle zhruba 500.000 bun\u011bk vpravili do zran\u011bn\u00ed \u010dty\u0159i prou\u017eky nervov\u00e9 tk\u00e1n\u011b z kotn\u00edku, kter\u00e9 um\u00edstili p\u0159es asi osmimilimetrov\u00e9 p\u0159eru\u0161en\u00ed lev\u00e9 \u010d\u00e1sti m\u00edchy. Podle v\u011bdc\u016f bu\u0148ky za pomoci zm\u00edn\u011bn\u00e9ho nervov\u00e9ho p\u0159emost\u011bn\u00ed po\u0161kozen\u00e9 m\u00ed\u0161n\u00ed oblasti op\u011bt propojily p\u0159eru\u0161en\u00e1 nervov\u00e1 vl\u00e1kna.<\/p>\n

Prvn\u00ed zlep\u0161en\u00ed Fidyka zaznamenal po t\u0159ech m\u011bs\u00edc\u00edch, kdy\u017e jeho lev\u00e9 stehno p\u0159ibralo svalovou hmotu. Po \u0161esti m\u011bs\u00edc\u00edch od transplantace u\u010dinil s pomoc\u00ed op\u011brn\u00e9 konstrukce prvn\u00ed kroky. Nyn\u00ed po dvou letech m\u016f\u017ee vyj\u00edt z rehabilita\u010dn\u00edho st\u0159ediska, st\u00e1le se ale mus\u00ed spol\u00e9hat na podp\u016frn\u00fd r\u00e1m.<\/p>\n

„Je \u00fa\u017easn\u00e9 sledovat, jak se regenerace m\u00edchy, tedy n\u011bco po \u0159adu let nemo\u017en\u00e9ho, st\u00e1v\u00e1 realitou,“ prohl\u00e1sil neurochirurg z vratislavsk\u00e9 univerzity Pawel Tabakow, kter\u00fd st\u00e1l v \u010dele polsk\u00e9ho v\u011bdeck\u00e9ho t\u00fdmu.<\/p>\n","protected":false},"excerpt":{"rendered":"

Pol\u00e1k Darek Fidyka, kter\u00fd byl po \u00fatoku no\u017eem v roce 2010 od hrudi dol\u016f paralyzov\u00e1n, m\u016f\u017ee po unik\u00e1tn\u00ed transplantaci \u010dichov\u00fdch bun\u011bk do posti\u017een\u00e9 oblasti m\u00edchy […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":4333,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-18032","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/18032","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18032"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/18032\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/4333"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18032"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18032"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18032"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}