Ji\u017e nen\u00ed daleko doba, kdy l\u00e9ka\u0159i budou schopni vyl\u00e9\u010dit lidi s poruchou m\u00edchy, kte\u0159\u00ed jsou dosud odk\u00e1z\u00e1ni na invalidn\u00ed voz\u00edk. V\u011bdci z \u00dastavu experiment\u00e1ln\u00ed medic\u00edny nyn\u00ed testuj\u00ed l\u00e9\u010dbu amyotrofick\u00e9 later\u00e1ln\u00ed skler\u00f3zy pomoc\u00ed kmenov\u00fdch bun\u011bk. <\/p>\n
Toto z\u00e1va\u017en\u00e9 neurologick\u00e9 onemocn\u011bn\u00ed vede k postupn\u00e9mu selh\u00e1v\u00e1n\u00ed \u017eivotn\u00edch funkc\u00ed \u010dlov\u011bka, kter\u00fd se s postupuj\u00edc\u00ed nemoc\u00ed p\u0159estane h\u00fdbat, pozd\u011bji i polykat a\u017e nakonec um\u00edr\u00e1. Do klinick\u00fdch zkou\u0161ek v pra\u017esk\u00e9 Fakultn\u00ed nemocnici v Motole bylo za\u0159azeno 13 pacient\u016f s t\u00edmto onemocn\u011bn\u00edm. <\/p>\n
„O v\u00fdsledc\u00edch se je\u0161t\u011b ned\u00e1 hovo\u0159it, proto\u017ee to chv\u00edli trv\u00e1. Za\u010dali jsme v polovin\u011b minul\u00e9ho roku, ale u\u017e se uk\u00e1zalo, \u017ee je to bezpe\u010dn\u00e9 a \u017e\u00e1dn\u00fd pacient nem\u011bl komplikace, ani se nezhor\u0161il,“ uvedla vedouc\u00ed v\u011bdeck\u00e9ho t\u00fdmu Eva Sykov\u00e1, kter\u00e1 v \u00fastavu vede v\u00fdzkum i dal\u0161\u00edch degenerativn\u00edch onemocn\u011bn\u00ed a poran\u011bn\u00ed mozku a m\u00edchy.<\/p>\n
Na v\u00fdzkumu l\u00e9\u010dby amyotrofick\u00e9 later\u00e1ln\u00ed skler\u00f3zy se v \u00fastavu Akademie v\u011bd \u010cR pracuje zhruba p\u011bt let. N\u00e1lezy u zv\u00ed\u0159at podle Sykov\u00e9 prok\u00e1zaly, \u017ee je mo\u017en\u00e9 zpomalit postup choroby. Na z\u00e1klad\u011b toho navrhli v\u011bdci klinickou zkou\u0161ku, kterou schv\u00e1lil St\u00e1tn\u00ed \u00fastav pro kontrolu l\u00e9\u010div.<\/p>\n
V\u011bdci a l\u00e9ka\u0159i nyn\u00ed sleduj\u00ed, zda l\u00e9\u010dba pomoc\u00ed kmenov\u00fdch bun\u011bk zpomal\u00ed chorobu tak\u00e9 u lid\u00ed. Vyu\u017e\u00edvaj\u00ed bu\u0148ky kostn\u00ed d\u0159en\u011b, vlastn\u00ed bu\u0148ky pacienta, kter\u00e9 se vyberou a rozmno\u017e\u00ed. „Tento proces trv\u00e1 p\u0159ibli\u017en\u011b t\u0159i t\u00fddny, pak jsou pacientovi pod\u00e1ny,“ uvedla Sykov\u00e1.<\/p>\n
Onemocn\u011bn\u00ed podle n\u00ed nen\u00ed p\u0159\u00edli\u0161 \u010dast\u00e9, v \u010cesku se eviduj\u00ed des\u00edtky p\u0159\u00edpad\u016f. Pr\u016fm\u011brn\u00e1 d\u00e9lka \u017eivota pacient\u016f s amyotrofickou later\u00e1ln\u00ed skler\u00f3zou se podle odborn\u00fdch studi\u00ed pohybuje zhruba od dvou do p\u011bti let od za\u010d\u00e1tku diagn\u00f3zy. Pouze deset procent nemocn\u00fdch p\u0159e\u017e\u00edv\u00e1 d\u00e9le ne\u017e deset let.<\/p>\n
Sykov\u00e1 se sv\u00fdm t\u00fdmem pracuje od Nov\u00e9ho roku v nov\u011b otev\u0159en\u00e9m V\u00fdzkumn\u00e9m centru bun\u011b\u010dn\u00e9 terapie a tk\u00e1\u0148ov\u00fdch n\u00e1hrad v pra\u017esk\u00e9 Kr\u010di, kter\u00e9 navazuje na Inova\u010dn\u00ed biomedic\u00ednsk\u00e9 centrum \u00dastavu experiment\u00e1ln\u00ed medic\u00edny. V\u00fdzkum kmenov\u00fdch bun\u011bk a biologick\u00fdch materi\u00e1l\u016f se zam\u011b\u0159uje na jejich vyu\u017eit\u00ed k reparac\u00edm, regenerac\u00edm a n\u00e1hrad\u00e1m po\u0161kozen\u00fdch org\u00e1n\u016f a tk\u00e1n\u00ed. <\/p>\n
invArena
\nMUDr. Jan \u010cin\u010dura<\/p>\n","protected":false},"excerpt":{"rendered":"
Ji\u017e nen\u00ed daleko doba, kdy l\u00e9ka\u0159i budou schopni vyl\u00e9\u010dit lidi s poruchou m\u00edchy, kte\u0159\u00ed jsou dosud odk\u00e1z\u00e1ni na invalidn\u00ed voz\u00edk. V\u011bdci z \u00dastavu experiment\u00e1ln\u00ed medic\u00edny […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-1818","post","type-post","status-publish","format-standard","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/1818","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1818"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/1818\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1818"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1818"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1818"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}