{"id":18253,"date":"2014-11-05T10:13:46","date_gmt":"2014-11-05T09:13:46","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=18253"},"modified":"2014-11-05T10:13:46","modified_gmt":"2014-11-05T09:13:46","slug":"pro-vyzkum-alzheimerovy-nemoci-se-hledaji-dobrovolnici","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=18253","title":{"rendered":"Pro v\u00fdzkum Alzheimerovy nemoci se hledaj\u00ed dobrovoln\u00edci"},"content":{"rendered":"

\u010ce\u0161t\u00ed v\u011bdci z\u0159ejm\u011b objevili kl\u00ed\u010d k rychlej\u0161\u00ed diagn\u00f3ze Alzheimerovy nemoci a nazna\u010dili cestu k objevu l\u00e9ku. Pot\u0159ebuj\u00ed v\u0161ak k dal\u0161\u00edmu v\u00fdzkumu dobrovoln\u00edky, kte\u0159\u00ed touto chorobou netrp\u00ed. <\/strong><\/p>\n

ilustra\u010dn\u00ed foto: photoXpress<\/em><\/p>\n

O objevu informoval Ale\u0161 Barto\u0161 z N\u00e1rodn\u00edho \u00fastavu du\u0161evn\u00edho zdrav\u00ed\/Psychiatrick\u00e9ho centra Praha, \u0161\u00e9f v\u00fdzkumn\u00e9ho t\u00fdmu, v n\u011bm\u017e jsou tak\u00e9 odborn\u00edci z Fakultn\u00ed nemocnice Kr\u00e1lovsk\u00e9 Vinohrady a z 1. l\u00e9ka\u0159sk\u00e9 fakulty Univerzity Karlovy.<\/p>\n

Alzheimerova nemoc je nevyl\u00e9\u010diteln\u00e9 onemocn\u011bn\u00ed mozku. Rozvoj se zat\u00edm d\u00e1 jen zpomalit, pokud se l\u00e9ky nasad\u00ed v\u010das. Trp\u00ed j\u00ed 140.000 \u010ce\u0161ek a \u010cech\u016f. Se st\u00e1rnut\u00edm nemocn\u00fdch p\u0159ib\u00fdv\u00e1, v roce 2050 m\u016f\u017ee b\u00fdt v \u010cR 225.000 pacient\u016f.<\/p>\n

P\u0159i Alzheimerov\u011b nemoci se do mozku ukl\u00e1daj\u00ed po\u0161kozen\u00e9 b\u00edlkoviny – tau protein. V po\u0161kozen\u00e9 form\u011b zan\u00e1\u0161ej\u00ed mozek a ni\u010d\u00ed ho. Tau protein a dal\u0161\u00ed b\u00edlkoviny\u00a0 tvo\u0159\u00ed kostru nervov\u00e9 bu\u0148ky. Pokud je kostra po\u0161kozena, nervov\u00e1 bu\u0148ka se m\u016f\u017ee rozpadnout.<\/p>\n

\u010cesk\u00fd v\u011bdeck\u00fd t\u00fdm se proto zam\u011b\u0159il na tau protein. Kdy\u017e se v\u011bdci zam\u011b\u0159ili na ur\u010ditou \u010d\u00e1st protil\u00e1tek, a to na p\u0159\u00edmo lok\u00e1ln\u011b vytvo\u0159en\u00e9 v bl\u00edzkosti nervov\u00e9 soustavy, zjistili, \u017ee u pacient\u016f s Alzheimerovou chorobou je mno\u017estv\u00ed v\u00fdznamn\u011b vy\u0161\u0161\u00ed ne\u017e u ostatn\u00edch. Zv\u00fd\u0161en\u00e9 protil\u00e1tky mohou souviset se zv\u00fd\u0161en\u00fdmi n\u00e1nosy po\u0161kozen\u00fdch b\u00edlkovin a rozpadem nervov\u00fdch bun\u011bk.<\/p>\n

„Zd\u00e1 se tedy, \u017ee tyto lok\u00e1ln\u011b zv\u00fd\u0161en\u00e9 protil\u00e1tky jsou relativn\u011b specifick\u00e9 pr\u00e1v\u011b pro Alzheimerovu nemoc,“ shrnul Barto\u0161.<\/p>\n

Hledaj\u00ed se dobrovoln\u00edci<\/strong><\/p>\n

V laborato\u0159i biochemie a patofyziologie mozku N\u00e1rodn\u00edho \u00fastavu du\u0161evn\u00edho zdrav\u00ed pl\u00e1nuje Barto\u0161\u016fv t\u00fdm poznatky ov\u011b\u0159it. Do studie chce za\u0159adit v\u00edce dal\u0161\u00edch pacient\u016f, a to s nemoc\u00ed v \u010dasn\u00e9m stadiu. Jejich s\u00e9ra a mozkom\u00ed\u0161n\u00ed moky budou vy\u0161et\u0159eny biochemick\u00fdmi metodami.<\/p>\n

Pro vytvo\u0159en\u00ed neuropsychologick\u00fdch test\u016f se nyn\u00ed hledaj\u00ed dobrovoln\u00edci. Pot\u0159eba jsou zdrav\u00ed mu\u017ei nad 50 let v\u011bku a zdrav\u00ed mu\u017ei i \u017eeny nad 85 let. V\u00fdzkum zohled\u0148uje i socioekonomick\u00fd status a vzd\u011bl\u00e1n\u00ed. Nedostatek je dobrovoln\u00edk\u016f s ni\u017e\u0161\u00edm vzd\u011bl\u00e1n\u00edm.<\/p>\n

Z\u00e1jemci o za\u0159azen\u00ed do studie musej\u00ed u\u017e\u00edvat \u010de\u0161tinu jako sv\u016fj mate\u0159sk\u00fd jazyk a b\u00fdt neurologicky i psychicky zdrav\u00ed. Nesm\u011bj\u00ed m\u00edt pocit poru\u0161en\u00e9 pam\u011bti. Vy\u0161et\u0159en\u00ed trv\u00e1 jednu a\u017e dv\u011b hodiny, provedou ho odborn\u00edci ve Fakultn\u00ed nemocnici Kr\u00e1lovsk\u00e9 Vinohrady.<\/p>\n

Objednat se lze na telefonu 267 162 344 se z\u00e1znamn\u00edkem nebo mailem adcentrum12@gmail.com.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

\u010ce\u0161t\u00ed v\u011bdci z\u0159ejm\u011b objevili kl\u00ed\u010d k rychlej\u0161\u00ed diagn\u00f3ze Alzheimerovy nemoci a nazna\u010dili cestu k objevu l\u00e9ku. Pot\u0159ebuj\u00ed v\u0161ak k dal\u0161\u00edmu v\u00fdzkumu dobrovoln\u00edky, kte\u0159\u00ed touto chorobou […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":15769,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-18253","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-spolecnost"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/18253","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=18253"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/18253\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/15769"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=18253"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=18253"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=18253"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}