{"id":22202,"date":"2017-04-22T08:46:37","date_gmt":"2017-04-22T06:46:37","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=22202"},"modified":"2017-04-22T08:46:37","modified_gmt":"2017-04-22T06:46:37","slug":"jak-jidlo-a-piti-meni-ucinky-leku","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=22202","title":{"rendered":"Jak j\u00eddlo a pit\u00ed m\u011bn\u00ed \u00fa\u010dinky l\u00e9k\u016f"},"content":{"rendered":"

Grapefruitov\u00e1 \u0161\u0165\u00e1va nebo t\u0159ezalka mohou dramaticky zm\u011bnit \u00fa\u010dinky n\u011bkter\u00fdch l\u00e9k\u016f. V\u011bt\u0161ina l\u00e9k\u00e1rn\u00edk\u016f u\u017e na to klienty upozor\u0148uje. Podobn\u00e9 efekty m\u00e1 v\u0161ak i \u0159ada potravin, n\u00e1poj\u016f, bylin nebo dokonce ko\u0159en\u00ed. Lid\u00e9 o nich nev\u011bd\u00ed prakticky nic.<\/strong><\/p>\n

P\u0159itom jde o ingredience velice b\u011b\u017en\u00e9. T\u0159eba takov\u00fd pep\u0159. Obsahuje kolem 9 % piperinu. Tato l\u00e1tka blokuje p\u0159irozen\u00e9 odbour\u00e1v\u00e1n\u00ed ur\u010dit\u00fdch l\u00e9k\u016f v tr\u00e1vic\u00edm traktu, co\u017e je docela nep\u0159\u00edjemn\u00fd probl\u00e9m. Farmaceutick\u00e9 firmy toti\u017e p\u0159esn\u011b v\u011bd\u00ed, jak\u00e9 mno\u017estv\u00ed jejich konkr\u00e9tn\u00edho l\u00e9ku se odbour\u00e1 u\u017e v tr\u00e1vic\u00edm traktu a jak\u00e9 se ho vst\u0159eb\u00e1 do organismu. To ur\u010duje jeho d\u00e1vkov\u00e1n\u00ed.<\/p>\n

Pokud ale l\u00e1tky, jako je piperin, zm\u011bn\u00ed m\u00edru odbour\u00e1v\u00e1n\u00ed, m\u016f\u017ee u n\u011bkter\u00fdch farmak doj\u00edt k docela rizikov\u00fdm situac\u00edm. P\u0159\u00edkladem jsou t\u0159eba pr\u00e1\u0161ky na span\u00ed. „Kv\u016fli tomu, \u017ee se v tr\u00e1vic\u00edm traktu zabrzd\u00ed jejich odbour\u00e1v\u00e1n\u00ed, se do organismu vst\u0159eb\u00e1 2,5kr\u00e1t vy\u0161\u0161\u00ed d\u00e1vka \u00fa\u010dinn\u00e9 l\u00e1tky, kterou obsahuj\u00ed,“ vysv\u011btluje PharmDr. Josef Suchop\u00e1r ze spole\u010dnosti Infopharm. „T\u00edm se v\u00fdznamn\u011b zv\u00fd\u0161\u00ed jejich tlumiv\u00fd efekt. Lid\u00e9, kte\u0159\u00ed si je vzali, se pak obvykle nec\u00edt\u00ed odpo\u010dat\u00ed, ale naopak unaven\u00ed, ospal\u00ed a mohou m\u00edt t\u0159eba za volantem zpomalen\u00e9 reakce, co\u017e snadno zv\u00fd\u0161\u00ed riziko nehody nebo hav\u00e1rie.“<\/p>\n

K vyvol\u00e1n\u00ed t\u011bchto i dal\u0161\u00edch negativn\u00edch \u00fa\u010dink\u016f u r\u016fzn\u00fdch l\u00e9k\u016f sta\u010d\u00ed velmi mal\u00e9 mno\u017estv\u00ed tohoto ko\u0159en\u00ed. P\u0159ibli\u017en\u011b takov\u00e9, jak\u00e9 vznikne rozemlet\u00edm jedn\u00e9 jeho kuli\u010dky.<\/p>\n

D\u016fle\u017eit\u00e1 pauza<\/p>\n

Obrana proti uveden\u00e9mu efektu je jednoduch\u00e1. „Pokud jste milovn\u00edky pep\u0159e a \u010dasto j\u00edm ko\u0159en\u00edte j\u00eddlo, sta\u010d\u00ed, kdy\u017e si uveden\u00e9 l\u00e9ky vezmete zhruba s dvouhodinov\u00fdm odstupem od chv\u00edle, kdy jste sn\u011bdli j\u00eddlo ochucen\u00e9 t\u00edmto pikantn\u00edm ko\u0159en\u00edm,“ \u0159\u00edk\u00e1 doktor Suchop\u00e1r. „Zm\u00edn\u011bn\u00fd efekt po t\u00e9to dob\u011b odezn\u00ed nebo je m\u00e1lo v\u00fdznamn\u00fd.“<\/p>\n

Podobn\u00e9 \u00fa\u010dinky m\u00e1 i dal\u0161\u00ed ko\u0159en\u00ed. Kar\u00ed, kurkuma, p\u00e1liv\u00e1 paprika a z\u00e1zvor. Pou\u017e\u00edvaj\u00ed se hojn\u011b v indick\u00e9 kuchyni, kterou si hodn\u011b lid\u00ed obl\u00edbilo. \u0158ada jich tak\u00e9 pravideln\u011b pije \u010daj z \u010derstv\u00e9ho z\u00e1zvoru na povzbuzen\u00ed organismu a podporu imunity. J\u00eddla a n\u00e1poje s t\u011bmito ingrediencemi maj\u00ed p\u0159esn\u011b opa\u010dn\u00fd efekt ne\u017e pep\u0159. „Pokud je u\u017e\u00edv\u00e1me t\u00fdden nebo \u010dtrn\u00e1ct dn\u00ed, mus\u00edme po\u010d\u00edtat s t\u00edm, \u017ee v\u00fdznamn\u011b zv\u00fd\u0161\u00ed m\u00edru odbour\u00e1v\u00e1n\u00ed ur\u010dit\u00fdch l\u00e9k\u016f, co\u017e sn\u00ed\u017e\u00ed jejich \u00fa\u010dinek,“ upozor\u0148uje Josef Suchop\u00e1r. <\/p>\n

„Tento efekt m\u016f\u017ee p\u0159etrv\u00e1vat a\u017e t\u00fdden.“
\nNa vst\u0159eb\u00e1n\u00ed l\u00e9k\u016f m\u00e1 v\u0161ak vliv i prost\u00fd fakt, jestli je spolkneme p\u0159ed j\u00eddlem, nebo po n\u011bm. Nap\u0159\u00edklad u tabletek, kter\u00e9 si vezmeme na bolest hlavy, b\u00fdv\u00e1 rychlej\u0161\u00ed n\u00e1stup \u00fa\u010dink\u016f v prv\u00e9m p\u0159\u00edpad\u011b a mnohem pomalej\u0161\u00ed v tom druh\u00e9m.<\/p>\n

12 pilulek m\u00edsto jedn\u00e9<\/p>\n

Zelen\u00fd \u010daj je n\u00e1poj, kter\u00fd m\u00e1 na na\u0161e zdrav\u00ed \u0159adu pozitivn\u00edch \u00fa\u010dink\u016f. I on vyvol\u00e1v\u00e1 v tr\u00e1vic\u00edm traktu podobn\u00fd efekt jako pep\u0159. Pokud j\u00edm zapijeme t\u0159eba l\u00e9ky pou\u017e\u00edvan\u00e9 p\u0159i zv\u00fd\u0161en\u00e9 hladin\u011b cholesterolu, kter\u00e9 obsahuj\u00ed \u00fa\u010dinnou l\u00e1tku simvastatin, vst\u0159eb\u00e1 se ho do krve tak\u00e9 2,5kr\u00e1t v\u00edc ne\u017e norm\u00e1ln\u011b. T\u00edm se zv\u011bt\u0161\u00ed nejen jeho p\u016fsoben\u00ed, ale i vedlej\u0161\u00ed efekty. Posti\u017een\u00e9ho \u010dlov\u011bka pak snadno potr\u00e1p\u00ed nap\u0159\u00edklad slabost sval\u016f, jejich bolesti, p\u0159\u00edpadn\u011b se m\u016f\u017ee projevit negativn\u00ed vliv na j\u00e1tra nebo i dal\u0161\u00ed pot\u00ed\u017ee.<\/p>\n

Opa\u010dn\u011b \u00fa\u010dinkuj\u00ed n\u00e1poje, jako je t\u0159eba jable\u010dn\u00fd mo\u0161t.
\nTen blokuje jednu z cest, kudy se ur\u010dit\u00e9 l\u00e9ky dost\u00e1vaj\u00ed z tr\u00e1vic\u00edho traktu do krve. Nap\u0159\u00edklad u atenololu, l\u00e9ku, kter\u00fd l\u00e9ka\u0159i p\u0159edepisuj\u00ed na zv\u00fd\u0161en\u00fd krevn\u00ed tlak nebo na nemoci srdce, sn\u00ed\u017e\u00ed jeho vst\u0159eb\u00e1v\u00e1n\u00ed a\u017e o 80 %. Pokud k tomu dojde jednor\u00e1zov\u011b, organismus si s t\u00edm obvykle n\u011bjak porad\u00ed. Kdy\u017e k tomu ale doch\u00e1z\u00ed \u010dasto, hroz\u00ed \u0161patn\u00e1 kompenzace zdravotn\u00edch pot\u00ed\u017e\u00ed, na kter\u00e9 je u\u017e\u00edv\u00e1me.<\/p>\n

Dal\u0161\u00edm p\u0159\u00edkladem je pomelo, p\u0159\u00edpadn\u011b \u0161\u0165\u00e1va z n\u011bj. Sni\u017euje p\u016fsoben\u00ed sildenafilu, tedy \u00fa\u010dinn\u00e9 l\u00e1tky viagry, zhruba o 40 %. „Tak\u00e9 \u0159ada l\u00e9k\u016f na osteopor\u00f3zu b\u00fdv\u00e1 citliv\u00fdch na to, \u010d\u00edm je zap\u00edj\u00edme,“ \u0159\u00edk\u00e1 doktor Suchop\u00e1r. „Nap\u0159\u00edklad k\u00e1va a miner\u00e1lka zhor\u0161uj\u00ed jejich vst\u0159eb\u00e1v\u00e1n\u00ed, a pokud je pijeme pravideln\u011b, tak i l\u00e9\u010dbu t\u00e9to choroby. Pacienti by je proto m\u011bli zap\u00edjet pouze \u010distou vodou.“<\/p>\n

Pokud sn\u00edme grapefruit nebo vypijeme \u0161\u0165\u00e1vu z n\u011bj a vezmeme si l\u00e9k na cholesterol se simvastatinem, zv\u00fd\u0161\u00edme t\u00edm mno\u017estv\u00ed \u00fa\u010dinn\u00e9 l\u00e1tky v organismu 12kr\u00e1t. Je to tedy podobn\u00e9, jako kdybychom m\u00edsto jedn\u00e9 tabletky spolkli 12 t\u011bchto pr\u00e1\u0161k\u016f. I v tomto p\u0159\u00edpad\u011b v\u0161ak obvykle sta\u010d\u00ed ud\u011blat n\u011bkolikahodinovou pauzu mezi ovocem a pilulkou.<\/p>\n

T\u0159ezalka ru\u0161\u00ed antikoncepci<\/p>\n

V posledn\u00ed dob\u011b stoup\u00e1 popularita bylin. \u0158ada lid\u00ed pou\u017e\u00edv\u00e1 nap\u0159\u00edklad t\u0159ezalku na leh\u010d\u00ed a st\u0159edn\u00ed deprese nebo na sez\u00f3nn\u00ed afektivn\u00ed poruchu vyvolanou \u0161erem, tedy nedostatkem slune\u010dn\u00edho sv\u011btla. Pro tu b\u00fdv\u00e1 typick\u00e1 \u00fanava, ospalost, podr\u00e1\u017ed\u011bnost, pot\u00ed\u017ee se soust\u0159ed\u011bn\u00edm nebo se sp\u00e1nkem atd. T\u0159ezalka v\u0161ak z\u00e1rove\u0148 zvy\u0161uje odbour\u00e1v\u00e1n\u00ed l\u00e9k\u016f a zmen\u0161uje jejich absorpci. Kv\u016fli tomu sni\u017euje jejich \u00fa\u010dinnost. U \u017een, kter\u00e9 bylinu u\u017e\u00edvaj\u00ed pravideln\u011b a z\u00e1rove\u0148 berou hormon\u00e1ln\u00ed antikoncepci, m\u016f\u017ee zv\u00fd\u0161it riziko necht\u011bn\u00e9ho ot\u011bhotn\u011bn\u00ed.<\/p>\n

„Kdy\u017e v\u011bdci zkoumali \u010detnost a z\u00e1va\u017enost tohoto efektu, zjistili v jedn\u00e9 ze studi\u00ed nap\u0159\u00edklad to, \u017ee z dvan\u00e1cti \u017een u\u017e\u00edvaj\u00edc\u00edch t\u0159ezalku a antikoncep\u010dn\u00ed pilulky do\u0161lo u t\u0159\u00ed z nich k ovulaci,“ \u0159\u00edk\u00e1 doktor Suchop\u00e1r. „Tedy k tomu, \u017ee antikoncepce p\u0159estala fungovat.“<\/p>\n

Hl\u00eddat je t\u0159eba i dal\u0161\u00ed byliny<\/p>\n

L\u00e9ka\u0159i, kte\u0159\u00ed v \u010cR praktikuj\u00ed tradi\u010dn\u00ed \u010d\u00ednskou medic\u00ednu, doporu\u010duj\u00ed klient\u016fm u chorob srdce, ale i na dal\u0161\u00ed pot\u00ed\u017ee, \u0161alv\u011bj \u010dervenoko\u0159ennou, takzvan\u00fd dan-\u0161en. Pokud ji v\u0161ak pacienti berou z\u00e1rove\u0148 s l\u00e9kem na sn\u00ed\u017een\u00ed vysok\u00e9ho cholesterolu, kter\u00fd obsahuje \u00fa\u010dinnou l\u00e1tku simvastatin, mohou t\u00edm srazit jeho efekty na polovinu a u dlouhodob\u00e9ho u\u017e\u00edv\u00e1n\u00ed je\u0161t\u011b n\u00ed\u017e. Obvykle pom\u016f\u017ee zm\u011bna l\u00e9ku, konkr\u00e9tn\u011b za rosuvastatin, kter\u00fd se odbour\u00e1v\u00e1 odli\u0161nou cestou.<\/p>\n

Takto bychom mohli dlouze pokra\u010dovat ve v\u00fd\u010dtu dal\u0161\u00edch l\u00e9k\u016f a mo\u017en\u00fdch vliv\u016f. Podstatn\u00e9 je pt\u00e1t se na n\u011b l\u00e9ka\u0159e nebo l\u00e9k\u00e1rn\u00edka. N\u011bkter\u00e9 l\u00e9k\u00e1rny nab\u00edzej\u00ed tyto konzultace jako bezplatnou slu\u017ebu.<\/p>\n","protected":false},"excerpt":{"rendered":"

Grapefruitov\u00e1 \u0161\u0165\u00e1va nebo t\u0159ezalka mohou dramaticky zm\u011bnit \u00fa\u010dinky n\u011bkter\u00fdch l\u00e9k\u016f. V\u011bt\u0161ina l\u00e9k\u00e1rn\u00edk\u016f u\u017e na to klienty upozor\u0148uje. Podobn\u00e9 efekty m\u00e1 v\u0161ak i \u0159ada potravin, n\u00e1poj\u016f, […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":14125,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-22202","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/22202","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=22202"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/22202\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/14125"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=22202"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=22202"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=22202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}