{"id":23565,"date":"2015-11-20T08:17:21","date_gmt":"2015-11-20T07:17:21","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=23565"},"modified":"2015-11-20T08:17:30","modified_gmt":"2015-11-20T07:17:30","slug":"vedci-porucha-reci-muze-byt-predzvesti-parkinsonovy-nemoci","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=23565","title":{"rendered":"V\u011bdci: Porucha \u0159e\u010di m\u016f\u017ee b\u00fdt p\u0159edzv\u011bst\u00ed Parkinsonovy nemoci"},"content":{"rendered":"

Porucha \u0159e\u010di m\u016f\u017ee b\u00fdt p\u0159edzv\u011bst\u00ed Parkinsonovy nemoci, zjistili v\u011bdci na neurologick\u00e9 klinice prvn\u00ed l\u00e9ka\u0159sk\u00e9 fakulty UK a V\u0161eobecn\u00e9 fakultn\u00ed nemocnice z anal\u00fdz hlasu a \u0159e\u010di pacient\u016f.<\/strong><\/p>\n

Anal\u00fdza \u0159e\u010di tak m\u016f\u017ee b\u00fdt vod\u00edtkem p\u0159i v\u010dasn\u00e9 diagn\u00f3ze Parkinsonovy nemoci i dal\u0161\u00edch neurodegenerativn\u00edch onemocn\u011bn\u00ed, sd\u011blil p\u0159ednosta kliniky Ev\u017een R\u016f\u017ei\u010dka. V\u010dasn\u00e1 diagn\u00f3za je z\u00e1sadn\u00ed pro dal\u0161\u00ed vyhl\u00eddky pacienta a co nejrychlej\u0161\u00ed nasazen\u00ed l\u00e9\u010dby. Parkinsonova choroba se projevuje t\u0159esem, \u0161patnou koordinac\u00ed pohyb\u016f, ztuhlost\u00ed a psychick\u00fdmi poruchami.<\/p>\n

„Hlavn\u00ed pohybov\u00e9 p\u0159\u00edznaky t\u011bchto onemocn\u011bn\u00ed se projevuj\u00ed a\u017e p\u0159i posti\u017een\u00ed zna\u010dn\u00e9 \u010d\u00e1sti mozkov\u00fdch bun\u011bk, zat\u00edmco zm\u011bny v \u0159e\u010di jim mohou dlouho p\u0159edch\u00e1zet,“ vysv\u011btlil p\u0159ednosta. Parkinsonova choroba je po Alzheimerov\u011b nemoci nej\u010dast\u011bj\u0161\u00ed neurodegenerativn\u00ed onemocn\u011bn\u00ed star\u0161\u00edho v\u011bku, m\u016f\u017ee se ale objevit i p\u0159ed \u010dty\u0159ic\u00edtkou. V \u010cesku je podle odhadu 100 a\u017e 200 pacient\u016f na 100.000 obyvatel.<\/p>\n

Studie, kterou t\u00fdm neurologick\u00e9 kliniky pr\u00e1v\u011b publikoval v mezin\u00e1rodn\u00edm odborn\u00e9m \u010dasopise Sleep Medicine, prok\u00e1zala poruchy \u0159e\u010di u pacient\u016f, kte\u0159\u00ed trp\u00ed poruchou chov\u00e1n\u00ed v REM sp\u00e1nku, tedy ve f\u00e1zi, kdy se zdaj\u00ed sny. Projevuje se zjevn\u011b pro\u017e\u00edvan\u00fdmi sny, hlasit\u00fdmi zvuky a prudk\u00fdmi pohyby, je\u017e mohou v\u00e9st ke zran\u011bn\u00ed. Pokud t\u011bmito sny \u010dlov\u011bk trp\u00ed, je ve vysok\u00e9m riziku, \u017ee se u n\u011bj pozd\u011bji objev\u00ed Parkinsonova choroba nebo jin\u00e9 onemocn\u011bn\u00ed nervov\u00e9ho syst\u00e9mu.<\/p>\n

„Odhady rozvoje Parkinsonovy nemoci jsou 33 procent p\u0159i p\u011btilet\u00e9m trv\u00e1n\u00ed t\u00e9to specifick\u00e9 poruchy sp\u00e1nku, 76 procent p\u0159i deseti letech a 91 procent, pokud trv\u00e1 14 let. Pomoc\u00ed anal\u00fdzy \u0159e\u010di jsme schopni vytipovat pacienty, u nich\u017e se tato choroba z\u0159ejm\u011b ji\u017e rozv\u00edj\u00ed,“ \u0159ekl profesor.<\/p>\n

Hlavn\u00edm \u0159e\u0161itelem t\u00fdmu analyzuj\u00edc\u00edho poruchy \u0159e\u010di je Jan Rusz z katedry teorie obvod\u016f Fakulty elektrotechnick\u00e9 \u010cVUT. Sleduje v\u00fdvoj metod zalo\u017een\u00fdch na digit\u00e1ln\u00edm zpracov\u00e1n\u00ed akustick\u00e9ho sign\u00e1lu \u0159e\u010di. „\u0158e\u010d je ovl\u00e1d\u00e1na velk\u00fdm mno\u017estv\u00edm sval\u016f a zapojuje se do n\u00ed n\u011bkolik mozkov\u00fdch center. Jej\u00ed porucha je jedn\u00edm z prvn\u00edch sign\u00e1l\u016f onemocn\u011bn\u00ed mozku,“ \u0159ekl.<\/p>\n

\u0158e\u010d se d\u00e1 rozd\u011blit do 40 dimenz\u00ed, k nim\u017e pat\u0159\u00ed intonace, hlasitost, rytmus \u010di artikulace. Pacient p\u0159i vy\u0161et\u0159en\u00ed mluv\u00ed do mikrofonu z\u00e1znamov\u00e9ho p\u0159\u00edstroje a postupn\u011b pln\u00ed t\u0159i \u00fakoly – prvn\u00edm je hlubok\u00fd n\u00e1dech s co nejdel\u0161\u00edm vysloven\u00edm hl\u00e1sky AAA, dal\u0161\u00edm je opakov\u00e1n\u00ed ur\u010dit\u00fdch slabik a t\u0159et\u00edm \u010detba kr\u00e1tk\u00e9ho odstavce. Nahr\u00e1vka je digit\u00e1ln\u011b zpracov\u00e1na, program umo\u017e\u0148uje objektivn\u011bj\u0161\u00ed vyhodnocen\u00ed ne\u017e dosud u\u017e\u00edvan\u00e9 poslechov\u00e9 testy.<\/p>\n

Do budoucna t\u00fdm pl\u00e1nuje roz\u0161\u00ed\u0159it v\u00fdzkum poruch \u0159e\u010di na dal\u0161\u00ed onemocn\u011bn\u00ed nervov\u00e9ho syst\u00e9mu a v\u00fdvoj nov\u00fdch technologi\u00ed. Dlouhodob\u00fdm c\u00edlem je v\u00fdvoj aplikace pro chytr\u00e9 telefony, kter\u00e1 by p\u0159i b\u011b\u017en\u00e9m pou\u017e\u00edv\u00e1n\u00ed pomohla vyhled\u00e1vat ohro\u017een\u00e9 pacienty.<\/p>\n","protected":false},"excerpt":{"rendered":"

Porucha \u0159e\u010di m\u016f\u017ee b\u00fdt p\u0159edzv\u011bst\u00ed Parkinsonovy nemoci, zjistili v\u011bdci na neurologick\u00e9 klinice prvn\u00ed l\u00e9ka\u0159sk\u00e9 fakulty UK a V\u0161eobecn\u00e9 fakultn\u00ed nemocnice z anal\u00fdz hlasu a \u0159e\u010di […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":15420,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-23565","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/23565","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23565"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/23565\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/15420"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23565"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=23565"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=23565"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}