Lup\u00e9nka neboli psori\u00e1za m\u011bla a mezi mnoha lidmi st\u00e1le m\u00e1 pov\u011bst nemoci, kter\u00e1 sice nikoho nezabije, ale je otravn\u00e1, a nav\u00edc se ned\u00e1 po\u0159\u00e1dn\u011b l\u00e9\u010dit. To prvn\u00ed plat\u00ed i nad\u00e1le, to druh\u00e9 u\u017e na\u0161t\u011bst\u00ed ne.<\/p>\n
Tr\u00e1p\u00ed v\u00e1s olupuj\u00edc\u00ed se k\u016f\u017ee a boj\u00edte se, \u017ee m\u00e1te lup\u00e9nku neboli psori\u00e1zu? To mus\u00ed potvrdit l\u00e9ka\u0159, proto jeho n\u00e1v\u0161t\u011bvu rad\u011bji neodkl\u00e1dejte. A v\u011bzte, \u017ee zdaleka ne ka\u017ed\u00fd podobn\u00fd probl\u00e9m znamen\u00e1 potvrzen\u00ed t\u00e9to diagn\u00f3zy. A i kdyby, mo\u017enosti l\u00e9\u010dby se za posledn\u00edch p\u00e1r let v\u00fdrazn\u011b zlep\u0161ily.
\nRozhodn\u011b se vyplat\u00ed, kdy\u017e si pacient uv\u011bdom\u00ed, \u017ee nejde toliko o ko\u017en\u00ed chorobu, ale \u017ee lup\u00e9nka je celkov\u00fdm autoimunitn\u00edm onemocn\u011bn\u00edm a \u017ee jej\u00ed vypuknut\u00ed \u00fazce souvis\u00ed s celkov\u00fdm \u017eivotn\u00edm stylem. Mimochodem, posledn\u00ed roky se medic\u00edna na lup\u00e9nku d\u00edv\u00e1 tak trochu jako na intern\u00ed onemocn\u011bn\u00ed. „Dop\u0159edu nelze ur\u010dit, u kter\u00e9ho jedince se psori\u00e1za vyskytne. Lup\u00e9nka nen\u00ed p\u0159\u00edmo d\u011bdi\u010dn\u00e1 choroba, ale je d\u011bdi\u010dn\u011b podm\u00edn\u011bn\u00e1. To znamen\u00e1, \u017ee pokud n\u011bkdo z rodiny trp\u00ed lup\u00e9nkou, je vy\u0161\u0161\u00ed riziko, \u017ee se m\u016f\u017ee u rodinn\u00e9ho p\u0159\u00edslu\u0161n\u00edka tak\u00e9 objevit,“ vysv\u011btluje l\u00e9ka\u0159 Spyridon Gkalpakiotis, prim\u00e1\u0159 ambulantn\u00ed \u010d\u00e1sti ko\u017en\u00ed kliniky pra\u017esk\u00e9 nemocnice na Vinohradech. L\u00e9ka\u0159i u\u017e dnes v\u011bd\u00ed, co lup\u00e9nku u disponovan\u00fdch jedinc\u016f spust\u00ed \u2013 t\u0159eba stres. Av\u0161ak nev\u011bd\u00ed, pro\u010d se tak d\u011bje. A\u010dkoli pro to medic\u00edna nem\u00e1 p\u0159\u00edm\u00e9 vysv\u011btlen\u00ed, nemoc m\u00edv\u00e1 t\u011b\u017e\u0161\u00ed pr\u016fb\u011bh u mu\u017e\u016f ne\u017e u \u017een. Je rovn\u011b\u017e zn\u00e1mo, \u017ee jej\u00ed pr\u016fb\u011bh zhor\u0161uje alkohol, kou\u0159en\u00ed, obezita a nervov\u00e9 vyp\u011bt\u00ed.<\/p>\n
Sv\u011bd\u00ed lokty, kolena i vlasat\u00e1 \u010d\u00e1st hlavy<\/p>\n
Nemoc, kter\u00e1 je \u2013 zjednodu\u0161en\u011b \u0159e\u010deno \u2013 z\u00e1n\u011btem k\u016f\u017ee, m\u00edv\u00e1 r\u016fzn\u00e9 podoby. Nej\u010dast\u011bji se lup\u00e9nka projevuje ost\u0159e ohrani\u010den\u00fdmi lo\u017eisky \u0161upinat\u00e9 k\u016f\u017ee nap\u0159\u00edklad na loktech \u010di kolenou, p\u0159\u00edpadn\u011b bedrech, v\u00fdjimkou nen\u00ed ani v\u00fdskyt na b\u0159i\u0161e i jin\u00fdch \u010d\u00e1stech t\u011bla. U n\u011bkter\u00fdch pacient\u016f m\u00edvaj\u00ed lo\u017eiska tvar kapek, rozeset\u00fdch po cel\u00e9m t\u011ble. N\u011bkte\u0159\u00ed nemocn\u00ed maj\u00ed bolav\u00e9 puch\u00fd\u0159ky napln\u011bn\u00e9 hnisem na dlan\u00edch, plosk\u00e1ch nohou a prstech, dal\u0161\u00ed m\u00edvaj\u00ed lo\u017eiska ve vlasat\u00e9 \u010d\u00e1sti hlavy.
\nProjevy nemoci jsou podle l\u00e9ka\u0159\u016f v\u011bt\u0161inou natolik jednozna\u010dn\u00e9, \u017ee mnohdy sta\u010d\u00ed pouze klinick\u00e9 vy\u0161et\u0159en\u00ed k\u016f\u017ee, neht\u016f a k\u0161tice. Lo\u017eiska psori\u00e1zy lemuje ost\u0159e ohrani\u010den\u00fd \u010derven\u00fd lem, na povrchu jsou \u0161upinky. Kdy\u017e se odstran\u00ed, co\u017e jde snadno, ranka krv\u00e1c\u00ed.
\nV nejasn\u00fdch p\u0159\u00edpadech l\u00e9ka\u0159 odebere drobn\u00fd vzorek k\u016f\u017ee pro vy\u0161et\u0159en\u00ed pod mikroskopem. Bohu\u017eel k m\u00e1n\u00ed nen\u00ed \u017e\u00e1dn\u00e9 jednoduch\u00e9 laboratorn\u00ed vy\u0161et\u0159en\u00ed z krve, kter\u00e9 by nemoc potvrdilo nebo vylou\u010dilo. V n\u011bkter\u00fdch p\u0159\u00edpadech je na m\u00edst\u011b vy\u0161et\u0159en\u00ed zam\u011b\u0159en\u00e9 na pl\u00eds\u0148ov\u00e9 onemocn\u011bn\u00ed, proto\u017ee to se v p\u0159\u00edpad\u011b posti\u017een\u00ed neht\u016f projevuje podobn\u011b.<\/p>\n
Klouby v ohro\u017een\u00ed<\/p>\n
U t\u0159iceti a\u017e \u010dty\u0159iceti procent nemocn\u00fdch se p\u0159id\u00e1vaj\u00ed tak\u00e9 probl\u00e9my s klouby. Tyto pot\u00ed\u017ee se ozna\u010duj\u00ed jako psoriatick\u00e1 artritida a bohu\u017eel p\u0159i nich doch\u00e1z\u00ed ke ztr\u00e1t\u011b funkce s nevratn\u00fdm po\u0161kozen\u00edm kloub\u016f.
\nVe v\u011bt\u0161in\u011b p\u0159\u00edpad\u016f se vyskytuje spolu s onemocn\u011bn\u00edm k\u016f\u017ee, ale m\u016f\u017ee se objevit tak\u00e9 samostatn\u011b, ani\u017e by \u010dlov\u011bk p\u0159edt\u00edm m\u011bl ko\u017en\u00ed projevy lup\u00e9nky. Proto je t\u0159eba jak\u00e9koli pot\u00ed\u017ee s klouby \u0159e\u0161it s l\u00e9ka\u0159em \u2013 pro spr\u00e1vnou l\u00e9\u010dbu je rozhoduj\u00edc\u00ed v\u010dasn\u00e1 diagnostika, na kter\u00e9 se pod\u00edl\u00ed dermatolog ve spolupr\u00e1ci s revmatologem.<\/p>\n
Na psori\u00e1zu plat\u00ed c\u00edlen\u00e1 l\u00e9\u010dba<\/p>\n
„M\u00e1me k dispozici velmi \u00fa\u010dinnou l\u00e9\u010dbu, jak lok\u00e1ln\u00ed, tak i zejm\u00e9na celkovou, kter\u00e1 dok\u00e1\u017ee p\u0159\u00edznaky onemocn\u011bn\u00ed minimalizovat a \u010dasto i \u00fapln\u011b eliminovat,“ uklid\u0148uje pacienty l\u00e9ka\u0159 Spyridon Gkalpakiotis.
\nNovinkou v celkov\u00e9 terapii je takzvan\u00e1 biologick\u00e1 l\u00e9\u010dba, kter\u00e1 dok\u00e1\u017ee c\u00edlen\u011b zablokovat kl\u00ed\u010dov\u00e9 b\u00edlkoviny imunitn\u00edho syst\u00e9mu, kter\u00e9 jinak vyvol\u00e1vaj\u00ed vznik z\u00e1n\u011btu u psori\u00e1zy.
\nV\u00fdhodou t\u00e9to l\u00e9\u010dby je \u2013 krom\u011b vysok\u00e9 \u00fa\u010dinnosti \u2013 i fakt, \u017ee ji pacienti velmi dob\u0159e sn\u00e1\u0161ej\u00ed, a to jak p\u0159i kr\u00e1tkodob\u00e9m, tak dlouhodob\u00e9m pod\u00e1v\u00e1n\u00ed. Pokud pacientovi l\u00e9\u010dba dob\u0159e zab\u00edr\u00e1 a dob\u0159e ji sn\u00e1\u0161\u00ed, pod\u00e1v\u00e1 se nep\u0159etr\u017eit\u011b cel\u00e9 roky.
\n„Moment\u00e1ln\u011b na na\u0161em pracovi\u0161ti m\u00e1me pacienty, kte\u0159\u00ed u\u017e\u00edvaj\u00ed biologickou l\u00e9\u010dbu t\u00e9m\u011b\u0159 deset let a jsou bu\u010f kompletn\u011b bez projev\u016f psori\u00e1zy, nebo maj\u00ed n\u011bjak\u00e9 minim\u00e1ln\u00ed projevy,“ \u0159ekl za vinohradskou ambulanci Spyridon Gkalpakiotis. Biologick\u00e1 terapie je k dispozici bu\u010f v podko\u017en\u00edch injekc\u00edch, nebo v nitro\u017eiln\u00ed infuzi.
\nJej\u00ed v\u00fdhodou je, \u017ee m\u00e1 m\u00e9n\u011b vedlej\u0161\u00edch \u00fa\u010dink\u016f ne\u017e celkov\u00e9 l\u00e9ky pod\u00e1van\u00e9 p\u0159i syst\u00e9mov\u00e9 l\u00e9\u010db\u011b, kter\u00e1 se dnes p\u0159edepisuje zejm\u00e9na lidem s t\u011b\u017e\u0161\u00edmi formami nemoci. Krom toho se pou\u017e\u00edvaj\u00ed lok\u00e1ln\u00ed p\u0159\u00edpravky k o\u0161et\u0159en\u00ed k\u016f\u017ee a tak\u00e9 fototerapie \u010dili l\u00e9\u010dba sv\u011btlem.<\/p>\n
P\u0159i nespokojenosti hledejte druh\u00fd l\u00e9ka\u0159sk\u00fd n\u00e1zor<\/p>\n
„Lup\u00e9nka sni\u017euje kvalitu \u017eivota pacient\u016f. Pacienti jsou \u010dasto frustrov\u00e1ni z nedostate\u010dn\u00e9ho efektu l\u00e9\u010dby a je pravda, \u017ee n\u011bkte\u0159\u00ed hledaj\u00ed pomoc u alternativn\u00edch metod,“ konstatuje doktor Gkalpakiotis. Pozor by si v\u0161ak m\u011bli d\u00e1t na to, \u017ee \u017e\u00e1dn\u00e1 takov\u00e1 metoda nepro\u0161la klinick\u00fdm zkou\u0161en\u00edm podle p\u0159\u00edsn\u00fdch a standardizovan\u00fdch pravidel, a neprok\u00e1zala tak, \u017ee je \u00fa\u010dinn\u00e1 a bezpe\u010dn\u00e1. Nav\u00edc v\u011bt\u0161ina alternativn\u00edch lok\u00e1ln\u00edch prepar\u00e1t\u016f nebo metod b\u00fdv\u00e1 drah\u00e1.
\n„Proto j\u00e1 sp\u00ed\u0161e rad\u00edm pacient\u016fm, \u017ee pokud jsou nespokojeni s l\u00e9\u010dbou u sv\u00e9ho dermatologa, m\u011bli by se obr\u00e1tit na jin\u00e9ho ko\u017en\u00edho l\u00e9ka\u0159e pro druh\u00fd n\u00e1zor,“ doporu\u010duje l\u00e9ka\u0159.<\/p>\n
—<\/p>\n
Nemoc u disponovan\u00fdch jedinc\u016f spou\u0161t\u00ed stres. Jej\u00ed pr\u016fb\u011bh zhor\u0161uje alkohol, kou\u0159en\u00ed, obezita a nervov\u00e9 vyp\u011bt\u00ed.<\/p>\n
Zdrav\u00e1 k\u016f\u017ee<\/p>\n
Norm\u00e1ln\u00ed obnova bun\u011bk: 3\u20134 t\u00fddny, za tuto dobu nov\u00e9 ko\u017en\u00ed bu\u0148ky doputuj\u00ed z nejhlub\u0161\u00ed vrstvy a\u017e k povrchu<\/p>\n
rohov\u00e1 vrstva z odum\u0159el\u00fdch, zrohovat\u011bl\u00fdch bun\u011bk<\/p>\n
granu\u00e1ln\u00ed vrstva, tzv. vrstva zrnit\u00fdch bun\u011bk, tvo\u0159\u00ed ji odum\u00edraj\u00edc\u00ed oplo\u0161t\u011bl\u00e9 bu\u0148ky<\/p>\n
spin\u00f3zn\u00ed vrstva, tvo\u0159\u00ed ji funk\u010dn\u00ed bu\u0148ky k\u016f\u017ee<\/p>\n
pigmentov\u00e1 bu\u0148ka<\/p>\n
baz\u00e1ln\u00ed vrstva, v n\u00ed ko\u017en\u00ed bu\u0148ky vyr\u016fstaj\u00ed<\/p>\n
K\u016f\u017ee posti\u017een\u00e1 lup\u00e9nkou<\/p>\n
Obnova bun\u011bk: pouh\u00e9 3\u20134 dny<\/p>\n
Vrstva rohov\u00fdch, odlupuj\u00edc\u00edch se bun\u011bk
\nz\u00e1n\u011bt
\nnahromad\u011bn\u00ed z\u00e1n\u011btliv\u00fdch bun\u011bk<\/p>\n
Pokud jeden z rodi\u010d\u016f trp\u00ed psori\u00e1zou, riziko rozvoje choroby u d\u00edt\u011bte je 30 procent, pokud maj\u00ed oba rodi\u010de lup\u00e9nku, riziko se zvy\u0161uje a\u017e na 70 procent.<\/p>\n
sklony k lup\u00e9nce se d\u011bd\u00ed, ale nemusej\u00ed se projevit. Naopak je mohou spustit tyto faktory:<\/p>\n
psychick\u00e9 vlivy, zejm\u00e9na chronick\u00fd stres infek\u010dn\u00ed onemocn\u011bn\u00ed a z\u00e1n\u011bty, typicky ang\u00edna a streptokokov\u00e9 infekce hormon\u00e1ln\u00ed vlivy, nemoc tak m\u016f\u017ee vypuknout t\u0159eba v pubert\u011b intern\u00ed choroby, jako je cukrovka<\/p>\n
mechanick\u00e9 a chemick\u00e9 vlivy, spou\u0161t\u011bc\u00edm faktorem se m\u016f\u017ee st\u00e1t \u00faraz l\u00e9ky, jako jsou beta-blok\u00e1tory, kter\u00e9 se pou\u017e\u00edvaj\u00ed k l\u00e9\u010db\u011b vysok\u00e9ho krevn\u00edho tlaku st\u0159\u00edd\u00e1n\u00ed ro\u010dn\u00edch obdob\u00ed \u0161patn\u00e1 \u017eivotospr\u00e1va, nap\u0159\u00edklad p\u0159em\u00edra alkoholu<\/p>\n
ANNA P\u0158\u00cdHODOV\u00c1
\nLidov\u00e9 noviny<\/p>\n","protected":false},"excerpt":{"rendered":"
Lup\u00e9nka neboli psori\u00e1za m\u011bla a mezi mnoha lidmi st\u00e1le m\u00e1 pov\u011bst nemoci, kter\u00e1 sice nikoho nezabije, ale je otravn\u00e1, a nav\u00edc se ned\u00e1 po\u0159\u00e1dn\u011b l\u00e9\u010dit. […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-24766","post","type-post","status-publish","format-standard","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/24766","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=24766"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/24766\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=24766"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=24766"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=24766"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}