{"id":25747,"date":"2016-06-07T10:15:17","date_gmt":"2016-06-07T08:15:17","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=25747"},"modified":"2016-06-07T10:15:17","modified_gmt":"2016-06-07T08:15:17","slug":"vedci-zkouseji-vypestovat-lidske-organy-v-embryich-prasat","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=25747","title":{"rendered":"V\u011bdci zkou\u0161ej\u00ed vyp\u011bstovat lidsk\u00e9 org\u00e1ny v embry\u00edch prasat"},"content":{"rendered":"

Nedostatek lidsk\u00fdch org\u00e1n\u016f k transplantac\u00edm se rozhodli vy\u0159e\u0161it ameri\u010dt\u00ed v\u011bdci t\u00edm, \u017ee je vyp\u011bstuj\u00ed v t\u011blech prasat. T\u00fdm z Kalifornsk\u00e9 univerzity vpravil lidskou DNA do prase\u010d\u00edch embry\u00ed, v nich\u017e m\u00e1 tento postup vytvo\u0159it lidsk\u00e9 org\u00e1ny.<\/strong><\/p>\n

ilustra\u010dn\u00ed foto: PhotoXpress<\/p>\n

Podle stanice BBC nyn\u00ed v\u00fdzkumn\u00edci zkou\u0161ej\u00ed, zdali se jim poda\u0159\u00ed v prase\u010d\u00edm z\u00e1rodku vytvo\u0159it lidskou slinivku. Podobn\u00e9 pokusy v\u0161ak vyvol\u00e1vaj\u00ed i kritick\u00e9 reakce kv\u016fli obav\u011b z mo\u017en\u00e9ho genetick\u00e9ho ovlivn\u011bn\u00ed mozku zv\u00ed\u0159at.<\/p>\n

V\u011bdci nejprve od\u0148ali z \u010derstv\u011b oplodn\u011bn\u00e9ho embrya \u010d\u00e1st prase\u010d\u00ed DNA, \u010d\u00edm\u017e vznikl prostor pro um\u00edst\u011bn\u00ed lidsk\u00fdch kmenov\u00fdch bun\u011bk schopn\u00fdch vyvinout se v jakoukoli t\u011blesnou tk\u00e1\u0148, v tomto p\u0159\u00edpad\u011b ve slinivku.<\/p>\n

„Douf\u00e1me, \u017ee se toto prase\u010d\u00ed embryo bude vyv\u00edjet norm\u00e1ln\u011b, ale slinivka bude vytvo\u0159ena t\u00e9m\u011b\u0159 v\u00fdhradn\u011b z lidsk\u00fdch bun\u011bk a bude vhodn\u00e1 k transplantaci pro pacienta,“ \u0159ekl BBC reproduk\u010dn\u00ed biolog Pablo Ross, kter\u00fd je vedouc\u00edm projektu.<\/p>\n

V prvn\u00edm pokusn\u00e9m kole se budou z\u00e1rodky vyv\u00edjet 28 dn\u00ed uvnit\u0159 dosp\u011bl\u00fdch samic, ne\u017e bude tk\u00e1\u0148 od\u0148ata a podrobena anal\u00fdze. V\u011bdci doufaj\u00ed, \u017ee pokud bude postup \u00fasp\u011b\u0161n\u00fd, m\u016f\u017ee v budoucnu v\u00e9st k vytv\u00e1\u0159en\u00ed org\u00e1n\u016f slo\u017een\u00fdch z lidsk\u00fdch bun\u011bk uvnit\u0159 prasat.<\/p>\n

Kalifornsk\u00fd t\u00fdm ji\u017e d\u0159\u00edve zkou\u0161el podobn\u00fd postup, av\u0161ak bez vytvo\u0159en\u00ed genetick\u00e9 niky odebr\u00e1n\u00edm prase\u010d\u00ed DNA. Podle Rosse se sice tk\u00e1\u0148 poda\u0159ilo \u010d\u00e1ste\u010dn\u011b vytvo\u0159it, av\u0161ak lidsk\u00e9 bu\u0148ky se nevyv\u00edjely odpov\u00eddaj\u00edc\u00edm zp\u016fsobem, nebo\u0165 se musely vyrovn\u00e1vat s konkurenc\u00ed t\u011bch prase\u010d\u00edch.<\/p>\n

Ve Spojen\u00fdch st\u00e1tech i jinde ve sv\u011bt\u011b vzbuzuj\u00ed podobn\u00e9 pokusy pohor\u0161en\u00ed ze strany profesn\u00edch organizac\u00ed i ve\u0159ejnosti, kter\u00e9 je ozna\u010duj\u00ed za nep\u0159\u00edpustn\u00e9 z\u00e1sahy do v\u00fdvoje \u017eivota. Nejv\u011bt\u0161\u00ed americk\u00e1 agentura financuj\u00edc\u00ed zdravotnick\u00e9 v\u00fdzkumy loni odm\u00edtla poskytovat finan\u010dn\u00ed zdroje na tento projekt kv\u016fli obav\u011b, \u017ee lidsk\u00e9 kmenov\u00e9 bu\u0148ky by se mohly pod\u00edlet na tvorb\u011b prase\u010d\u00edho mozku, kter\u00fd by se stal podobn\u011bj\u0161\u00edm tomu lidsk\u00e9mu. „Podle n\u00e1s je velmi mal\u00fd potenci\u00e1l pro to, aby se (v praseti) vyvinul lidsk\u00fd mozek, ale budeme tomu v\u011bnovat pozornost,“ dodal Ross.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nedostatek lidsk\u00fdch org\u00e1n\u016f k transplantac\u00edm se rozhodli vy\u0159e\u0161it ameri\u010dt\u00ed v\u011bdci t\u00edm, \u017ee je vyp\u011bstuj\u00ed v t\u011blech prasat. T\u00fdm z Kalifornsk\u00e9 univerzity vpravil lidskou DNA do […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":15033,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-25747","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/25747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25747"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/25747\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/15033"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25747"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25747"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}