O kysl\u00edk bojuje kv\u016fli smrteln\u00e9 nemoci \u010d\u00edm d\u00e1l v\u00edce lid\u00ed. Idiopatick\u00e1 plicn\u00ed fibr\u00f3za (IPF) ro\u010dn\u011b v \u010cesk\u00e9 republice zabije des\u00edtky pacient\u016f. Po\u0161kozuje plicn\u00ed skl\u00edpky, jizv\u00ed je \u2013 bere plochu k d\u00fdch\u00e1n\u00ed, pl\u00edce tuhnou a \u010dlov\u011bk se nem\u016f\u017ee nadechnout. Postup nemoci brzd\u00ed l\u00e9\u010dba, kter\u00e1 je v tuzemsku pouh\u00fdch 5 let. Pacienti se k n\u00ed v\u0161ak \u010dasto nedostanou, proto\u017ee se nemoc odhal\u00ed pozd\u011b.
\n
\nProjevy IPF l\u00e9ka\u0159i \u010dasto zam\u011b\u0148uj\u00ed za chronickou obstruk\u010dn\u00ed plicn\u00ed nemoc, z\u00e1pal plic \u010di srde\u010dn\u00ed selh\u00e1n\u00ed. Bez spr\u00e1vn\u00e9 l\u00e9\u010dby p\u0159itom IPF obvykle zab\u00edj\u00ed do 3 let. S l\u00e9\u010dbou ale m\u016f\u017ee pacient vzdorovat roky a zvy\u0161uje se jeho \u0161ance, \u017ee se do\u010dk\u00e1 transplantace plic.
\n\u201eVelk\u00e1 \u010d\u00e1st pacient\u016f nepova\u017euje zpo\u010d\u00e1tku poka\u0161l\u00e1v\u00e1n\u00ed a zad\u00fdch\u00e1v\u00e1n\u00ed za p\u0159\u00edznak t\u011b\u017ek\u00e9 nemoci, ale za projev st\u00e1rnut\u00ed, ztr\u00e1tu kondice, \u010di n\u00e1sledek kou\u0159en\u00ed. Mohou oddalovat n\u00e1v\u0161t\u011bvu l\u00e9ka\u0159e a velmi \u010dasto, kdy\u017e u\u017e se k n\u00ed odhodlaj\u00ed, odch\u00e1z\u00ed dom\u016f utvrzeni ve sv\u00e9m p\u0159esv\u011bd\u010den\u00ed, \u017ee \u201ejenom\u201c st\u00e1rnou,\u201c \u0159\u00edk\u00e1 prof. MUDr. Martina Va\u0161\u00e1kov\u00e1, PhD, p\u0159ednostka Pneumologick\u00e9 kliniky 1. l\u00e9ka\u0159sk\u00e9 fakulty UK a Thomayerovy nemocnice v Praze a p\u0159edsedkyn\u011b Sekce pro interstici\u00e1ln\u00ed plicn\u00ed procesy (SIPP) \u010cesk\u00e9 pneumologick\u00e9 a ftizeologick\u00e9 spole\u010dnosti. To potvrzuje i p\u0159\u00edb\u011bh b\u00fdval\u00e9ho tiska\u0159e, Radima Sou\u010dka (73), kter\u00fd zhor\u0161en\u00e9mu d\u00fdch\u00e1n\u00ed nep\u0159ikl\u00e1dal zprvu \u017e\u00e1dn\u00fd v\u00fdznam. \u201e\u0158\u00edkal jsem si \u2013 co taky chce\u0161? U\u017e se\u0161 star\u0161\u00ed, nen\u00ed divu, \u017ee se ti h\u016f\u0159 d\u00fdch\u00e1,\u201c popisuje situaci Radim Sou\u010dek. Pot\u00ed\u017ee s d\u00fdch\u00e1n\u00edm se v\u0161ak zhor\u0161ovaly a tak pan Sou\u010dek vyrazil za plicn\u00ed l\u00e9ka\u0159kou. \u201eKdy\u017e jsem j\u00ed o tom \u0159ekl, \u017ee h\u016f\u0159 d\u00fdch\u00e1m, p\u016fvodn\u011b tomu nep\u0159ikl\u00e1dala v\u011bt\u0161\u00ed d\u016fraz, je\u0161t\u011b jsme na t\u00e9ma \u017eertovali, \u017ee pot\u00ed\u017ee s d\u00fdch\u00e1n\u00edm m\u00e1 i ona. Po \u010dase j\u00ed to v\u0161ak nedalo a poslala m\u011b na specializovan\u00e9 odd\u011blen\u00ed do nemocnice v Kr\u010di. A tam u\u017e padla fin\u00e1ln\u00ed diagn\u00f3za \u2013 plicn\u00ed fibr\u00f3za,\u201c vzpom\u00edn\u00e1 pacient. Odborn\u00edci se tak rozhodli vyj\u00edt lidem vst\u0159\u00edc a zorganizovali dny otev\u0159en\u00fdch ambulanc\u00ed, kam mohou p\u0159ij\u00edt bez doporu\u010den\u00ed, poradit se a nechat vy\u0161et\u0159it plicn\u00edmi l\u00e9ka\u0159i.
\nJak prof. Va\u0161\u00e1kov\u00e1 uv\u00e1d\u00ed, IPF l\u00e9ka\u0159i \u010dasto diagnostikuj\u00ed pozd\u011b, v pokro\u010dil\u00e9m st\u00e1diu. Projevy IPF jsou lehce zam\u011bniteln\u00e9 za jin\u00e9 plicn\u00ed \u010di dokonce srde\u010dn\u00ed nemoci. \u201eIPF je mo\u017en\u00e9 jasn\u011b ur\u010dit p\u0159i poslechu \u2013 l\u00e9ka\u0159 sly\u0161\u00ed charakteristick\u00fd zvuk, p\u0159ipom\u00ednaj\u00edc\u00ed odep\u00edn\u00e1n\u00ed such\u00e9ho zipu. Lid\u00e9, kte\u0159\u00ed nemoc\u00ed trp\u00ed, m\u00edvaj\u00ed tak\u00e9 tzv. pali\u010dkovit\u00e9 prsty s nehty tvaru hodinov\u00e9ho skl\u00ed\u010dka,\u201c jmenuje prof. Va\u0161\u00e1kov\u00e1.
\nNemoc se ohla\u0161uje zprvu nen\u00e1padn\u011b, \u010dlov\u011bk se za\u010dne zad\u00fdch\u00e1vat do schod\u016f, pozd\u011bji i p\u0159i ch\u016fzi \u010di hovoru, v pokro\u010dil\u00e9m st\u00e1diu m\u00e1 pocit nedostatku vzduchu p\u0159i b\u011b\u017en\u00fdch denn\u00edch \u010dinnostech a v z\u00e1v\u011bru v\u011bnuje ve\u0161kerou energii tomu, aby se nadechl. \u201ePacienti s pokro\u010dilou plicn\u00ed fibr\u00f3zou mohou b\u00fdt po komplexn\u00edm p\u0159e\u0161et\u0159en\u00ed kandid\u00e1ty transplantace plic. V kone\u010dn\u00fdch f\u00e1z\u00edch nemoci jsou pacienti zcela odk\u00e1z\u00e1ni na kysl\u00edk, p\u0159\u00edpadn\u011b pocit nedostatku kysl\u00edku m\u016f\u017eeme m\u00edrnit i opi\u00e1ty,\u201c \u0159\u00edk\u00e1 prof. Va\u0161\u00e1kov\u00e1. Rychlost a v\u010dasnost diagn\u00f3zy je pro dal\u0161\u00ed pr\u016fb\u011bh nemoci naprosto kl\u00ed\u010dov\u00e1. V \u010dasn\u00fdch a m\u00e1lo pokro\u010dil\u00fdch f\u00e1z\u00edch nemoci toti\u017e dovedeme plicn\u00ed fibr\u00f3zu a \u00fabytek plicn\u00edch funkc\u00ed zpomalit pod\u00e1n\u00edm \u00fa\u010dinn\u00fdch l\u00e9k\u016f. Proto by ambulantn\u00ed l\u00e9ka\u0159i m\u011bli p\u0159i prvn\u00edm podez\u0159en\u00ed okam\u017eit\u011b pacienta odeslat do n\u011bkter\u00e9ho ze 17 Center pro diagnostiku a l\u00e9\u010dbu interstici\u00e1ln\u00edch plicn\u00edch proces\u016f, kam nyn\u00ed doputuje pouh\u00e1 \u010dtvrtina z odhadovan\u00fdch 2 000 pacient\u016f s IPF.
\nCo nejp\u0159esn\u011bj\u0161\u00ed informace o nemoci m\u00e1 p\u0159in\u00e9st registr idiopatick\u00e9 plicn\u00ed fibr\u00f3zy – EMPIRE, do n\u011bho\u017e se p\u0159ipojuj\u00ed evropsk\u00e9 zem\u011b, jako nap\u0159\u00edklad Slovensko, Ma\u010farsko, Polsko, Srbsko, \u010di Chorvatsko. V sou\u010dasn\u00e9 dob\u011b je v registru 984 pacient\u016f, z toho 610 z \u010cR, 71 z Ma\u010farska, 184 z Polska, 28 ze Srbska a 91 ze Slovenska. Odhadem nemoc\u00ed ve sv\u011bt\u011b trp\u00ed 5 milion\u016f lid\u00ed. IPF se p\u0159ev\u00e1\u017en\u011b vyskytuje u osob star\u0161\u00edch 45 let, sp\u00ed\u0161e mu\u017e\u016f. D\u016fvody vzniku nemoci nejsou dosud zn\u00e1my. \u201eV\u00edme o vlivu genetiky, kou\u0159en\u00ed, \u010di dlouhodob\u00e9m pobytu v pra\u0161n\u00fdch prostor\u00e1ch,\u201c dod\u00e1v\u00e1 prof. Va\u0161\u00e1kov\u00e1.
\nAby se pov\u011bdom\u00ed o nemoci roz\u0161\u00ed\u0159ilo mezi ve\u0159ejnost, otev\u0159ou se letos poprv\u00e9 – v r\u00e1mci Sv\u011btov\u00e9ho t\u00fddne IPF – ambulance plicn\u00edch l\u00e9ka\u0159\u016f lidem v cel\u00e9 \u010cesk\u00e9 republice. Letos vych\u00e1z\u00ed pacientsk\u00e1 bro\u017eura, nemoci se v\u011bnuje tak\u00e9 port\u00e1l www.plicnifibroza.cz, kter\u00fd nab\u00edz\u00ed kontakty na odborn\u00edky a informace o mo\u017enostech \u00fa\u010dasti v klinick\u00fdch studi\u00edch.<\/p>\n
O Sekci interstici\u00e1ln\u00edch plicn\u00edch proces\u016f (SIPP)
\nSIPP \u010cesk\u00e9 pneumologick\u00e9 a ftizeologick\u00e9 spole\u010dnosti v\u011bnuje speci\u00e1ln\u011b idiopatick\u00e9 plicn\u00ed fibr\u00f3ze velik\u00e9 \u00fasil\u00ed a krom\u011b snahy o roz\u0161\u00ed\u0159en\u00ed informac\u00ed o t\u00e9to nemoci mezi ostatn\u00ed l\u00e9ka\u0159skou, ale i laickou ve\u0159ejnost zalo\u017eila a vede i registr idiopatick\u00e9 plicn\u00ed fibr\u00f3zy EMPIRE (European Multipartner IPF registry). Ten krom\u011b center v \u010cesk\u00e9 republice zahrnuje i centra na Slovensku, v Polsku a Ma\u010farsku a p\u0159idru\u017euje se Srbsko, Slovinsko, Chorvatsko a Turecko. Registr d\u00e1v\u00e1 mo\u017enost nahl\u00e9dnout do epidemiologie IPF a do re\u00e1ln\u00fdch l\u00e9\u010debn\u00fdch v\u00fdsledk\u016f t\u00e9to nemoci, p\u0159i zav\u00e1d\u011bn\u00ed nov\u00fdch l\u00e9k\u016f na plicn\u00ed fibr\u00f3zu dle \u00fadaj\u016f z registru lze vid\u011bt, kolik pacient\u016f pro dan\u00fd l\u00e9k \u010di klinickou studii mohou l\u00e9ka\u0159i vyu\u017e\u00edt, a kter\u00fdm konkr\u00e9tn\u00edm pacient\u016fm nov\u00fd l\u00e9k nab\u00eddnout.
\nSIPP tak\u00e9 na z\u00e1klad\u011b mezin\u00e1rodn\u00edch doporu\u010den\u00ed a nov\u00fdch poznatk\u016f op\u0159en\u00fdch o medic\u00ednu zalo\u017eenou na d\u016fkazech sestavuje doporu\u010den\u00ed k diagnostice a l\u00e9\u010db\u011b jednotliv\u00fdch IPP. D\u00e1le se star\u00e1 o zaji\u0161t\u011bn\u00ed s\u00edt\u011b pracovi\u0161\u0165 specializovan\u00fdch na p\u00e9\u010di o pacienty s IPP, aby l\u00e9ka\u0159i v\u011bd\u011bli, kam se maj\u00ed se \u017e\u00e1dost\u00ed o konzultaci, dovy\u0161et\u0159en\u00ed pacienta, \u010di jeho l\u00e9\u010dbu obr\u00e1tit. Podporuje v\u00fdzkum a publika\u010dn\u00ed aktivitu v oblasti IPP na \u00fazem\u00ed \u010cR.<\/p>\n
Mark\u00e9ta Pudilov\u00e1
\nTiskov\u00e1 zpr\u00e1va<\/p>\n","protected":false},"excerpt":{"rendered":"
O kysl\u00edk bojuje kv\u016fli smrteln\u00e9 nemoci \u010d\u00edm d\u00e1l v\u00edce lid\u00ed. Idiopatick\u00e1 plicn\u00ed fibr\u00f3za (IPF) ro\u010dn\u011b v \u010cesk\u00e9 republice zabije des\u00edtky pacient\u016f. Po\u0161kozuje plicn\u00ed skl\u00edpky, jizv\u00ed […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":27092,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,9],"tags":[],"class_list":["post-26394","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/26394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=26394"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/26394\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/27092"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=26394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=26394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=26394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}