{"id":27721,"date":"2017-03-28T22:35:16","date_gmt":"2017-03-28T20:35:16","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=27721"},"modified":"2017-03-29T11:24:25","modified_gmt":"2017-03-29T09:24:25","slug":"vyzkumnici-v-brne-vyviji-lek-z-pupecniku-na-degenerativni-nemoci","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=27721","title":{"rendered":"V\u00fdzkumn\u00edci v Brn\u011b vyv\u00edj\u00ed l\u00e9k z pupe\u010dn\u00edku na degenerativn\u00ed nemoci"},"content":{"rendered":"

V\u00fdzkumn\u00edci v Brn\u011b cht\u011bj\u00ed ve spolupr\u00e1ci se soukrom\u00fdmi firmami vyvinout z bun\u011bk pupe\u010dn\u00edku l\u00e9k na imunitn\u00ed choroby a degenerativn\u00ed onemocn\u011bn\u00ed. Pom\u00e1hat m\u016f\u017ee nap\u0159\u00edklad po infarktu, mozkov\u00e9 p\u0159\u00edhod\u011b, u nemoci kloub\u016f nebo po transplantaci kostn\u00ed d\u0159en\u011b.<\/strong><\/p>\n

Novin\u00e1\u0159\u016fm to \u0159ekla vedouc\u00ed v\u00fdzkumu a l\u00e9ka\u0159sk\u00e1 \u0159editelka spole\u010dnosti PrimeCell Dagmar Hr\u016fzov\u00e1. L\u00e9k aplikovan\u00fd injek\u010dn\u011b by mohl b\u00fdt podle n\u00ed poprv\u00e9 pou\u017eit\u00fd p\u0159i klinick\u00e9m testov\u00e1n\u00ed v roce 2019, na trhu dostupn\u00fd pro celou EU by mohl b\u00fdt asi v roce 2024. K v\u00fdrob\u011b poslou\u017e\u00ed nov\u00fd p\u0159\u00edstroj bioreaktor.<\/p>\n

Na projektu s odhadovan\u00fdmi n\u00e1klady kolem 50 milion\u016f korun se spolu se spole\u010dnost\u00ed PrimeCell pod\u00edl\u00ed Mezin\u00e1rodn\u00ed centrum klinick\u00e9ho v\u00fdzkumu a korejsk\u00e1 firma Hans Biomed. \u010c\u00e1st n\u00e1klad\u016f zaplat\u00ed firmy, kter\u00e9 z\u00edskaly tak\u00e9 dotace od st\u00e1tu.<\/p>\n

Pupe\u010dn\u00edk, kter\u00fd spojuje novorozence s placentou matky, budou v\u00fdzkumn\u00edci z\u00edsk\u00e1vat po souhlasu rodi\u010d\u016f od novorozenc\u016f z Fakultn\u00ed nemocnice Brno. „Tk\u00e1\u0148 pupe\u010dn\u00edku je biologick\u00fdm odpadem, my z n\u011bj ale vyvineme l\u00e9k budoucnosti. Na\u0161e spole\u010dnost vytvo\u0159\u00ed l\u00e9k, Mezin\u00e1rodn\u00ed centrum klinick\u00e9ho v\u00fdzkumu ho bude testovat a Hans Biomed bude zkoumat dal\u0161\u00ed potenci\u00e1l odpadn\u00edch l\u00e1tek, kter\u00e9 n\u00e1m zbudou,“ uvedla Hr\u016fzov\u00e1.<\/p>\n

Podle n\u00ed m\u00e1 pupe\u010dn\u00edk mnoho cenn\u00fdch bun\u011bk. „Mohou ovlivnit imunitu, co\u017e chceme vyu\u017e\u00edt pro poruchy imunity nap\u0159\u00edklad u takzvan\u00e9 reakce \u0161t\u011bpu v\u016f\u010di hostiteli po transplantaci kostn\u00ed d\u0159en\u011b. D\u00e1le maj\u00ed bu\u0148ky i regenerativn\u00ed vlastnosti a dok\u00e1\u017eou nastartovat a zrychlit hojen\u00ed tk\u00e1n\u011b. To je dobr\u00e9 nap\u0159\u00edklad po infarktu, mozkov\u00e9 p\u0159\u00edhod\u011b nebo u kloubn\u00edho onemocn\u011bn\u00ed osteoartr\u00f3za,“ \u0159ekla Hr\u016fzov\u00e1<\/p>\n

Po odebr\u00e1n\u00ed pupe\u010dn\u00edku po porodu se pro v\u00fd\u017eivu a rozmno\u017een\u00ed bun\u011bk pou\u017eije bioreaktor, kter\u00fd firma PrimeCell po\u0159\u00eddila kv\u016fli v\u00fdrob\u011b l\u00e9ku za t\u0159i miliony korun. Podle Hr\u016fzov\u00e9 bioreaktor odhadem desetin\u00e1sobn\u011b nahrad\u00ed proces, p\u0159i kter\u00e9m by v\u00fdzkumn\u00edci vy\u017eivovali pupe\u010dn\u00edk pomoc\u00ed kultiva\u010dn\u00edch lahv\u00ed. T\u00edm ho nejen mnohon\u00e1sobn\u011b namno\u017e\u00ed, ale tak\u00e9 u\u0161et\u0159\u00ed n\u00e1klady a person\u00e1l.<\/p>\n

„Pupe\u010dn\u00edk obsahuje asi deset milion\u016f bun\u011bk. Kdy\u017e na n\u011bj nasad\u00edme bioreaktor, za t\u00fdden budeme m\u00edt 700 milion\u016f bun\u011bk. Ot\u00e1zkou testov\u00e1n\u00ed bude zjistit, jak moc m\u016f\u017eeme rozmno\u017eovat. Chceme ale vytvo\u0159it takov\u00fd l\u00e9k, kter\u00fd bude v kone\u010dn\u00e9m d\u016fsledku cenov\u011b dostupn\u00fd,“ dodala Hr\u016fzov\u00e1. Bu\u0148ky z jednoho pupe\u010dn\u00edku by m\u011bly po rozmno\u017een\u00ed pomoct des\u00edtk\u00e1m lid\u00ed. U ka\u017ed\u00e9ho ale bude jin\u00e1 d\u00e1vka podle v\u00e1hy a onemocn\u011bn\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"

V\u00fdzkumn\u00edci v Brn\u011b cht\u011bj\u00ed ve spolupr\u00e1ci se soukrom\u00fdmi firmami vyvinout z bun\u011bk pupe\u010dn\u00edku l\u00e9k na imunitn\u00ed choroby a degenerativn\u00ed onemocn\u011bn\u00ed. Pom\u00e1hat m\u016f\u017ee nap\u0159\u00edklad po infarktu, […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":5408,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-27721","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27721","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27721"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27721\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/5408"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27721"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27721"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27721"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}