{"id":27859,"date":"2017-04-05T19:53:45","date_gmt":"2017-04-05T17:53:45","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=27859"},"modified":"2017-04-05T19:53:45","modified_gmt":"2017-04-05T17:53:45","slug":"cesti-vedci-se-podileji-na-vyvoji-leciva-proti-krehkosti-ve-stari","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=27859","title":{"rendered":"\u010ce\u0161t\u00ed v\u011bdci se pod\u00edlej\u00ed na v\u00fdvoji l\u00e9\u010diva proti k\u0159ehkosti ve st\u00e1\u0159\u00ed"},"content":{"rendered":"

\u00dabytku svalov\u00e9 hmoty a s\u00edly ve st\u00e1\u0159\u00ed by v budoucnu mohlo zabr\u00e1nit l\u00e9\u010divo, na jeho\u017e v\u00fdvoji se pod\u00edlej\u00ed v\u011bdci z Univerzity Karlovy ve spolupr\u00e1ci s farmaceutick\u00fdmi firmami v r\u00e1mci projektu SPRINTT evropsk\u00e9 iniciativy IMI 2. Na dne\u0161n\u00ed tiskov\u00e9 konferenci p\u0159edstavila tento projekt Eva Topinkov\u00e1 z Geriatrick\u00e9 kliniky 1. l\u00e9ka\u0159sk\u00e9 fakulty Univerzity Karlovy. Je jedn\u00edm z p\u0159\u00edklad\u016f spolupr\u00e1ce Univerzity Karlovy a farmaceutick\u00e9ho pr\u016fmyslu.<\/strong><\/p>\n

Projekt SPRINTT, kter\u00fd zkoum\u00e1 fyzickou k\u0159ehkost senior\u016f, pat\u0159\u00ed podle Topinkov\u00e9 mezi velk\u00e9 evropsk\u00e9 projekty, v nich\u017e farmaceutick\u00fd pr\u016fmysl v\u00fdznamn\u011b p\u0159isp\u00edv\u00e1 sv\u00fdmi znalostmi a zku\u0161enostmi s uplatn\u011bn\u00edm v\u00fdsledk\u016f ze z\u00e1kladn\u00edho v\u00fdzkumu v klinick\u00e9 praxi. Jeho n\u00e1klady jsou asi 54 milion\u016f eur, zhruba 30 milion\u016f eur plat\u00ed Evropsk\u00e1 unie a 20 milion\u016f eur financuj\u00ed v\u011bcn\u00fdm pln\u011bn\u00edm farmaceutick\u00e9 firmy.<\/p>\n

Topinkov\u00e1 uvedla, \u017ee l\u00e9ka\u0159i dnes nejsou zvykl\u00ed diagnostikovat fyzickou k\u0159ehkost senior\u016f neboli sarkopenii. Ta je p\u0159\u00ed\u010dinou, pro\u010d star\u0161\u00ed lid\u00e9 pomaleji chod\u00ed, zvedaj\u00ed m\u00e1lo nohy nebo \u010dast\u011bji padaj\u00ed, co\u017e n\u011bkdy b\u00fdv\u00e1 p\u0159\u00ed\u010dinou r\u016fzn\u00fdch \u00faraz\u016f a dal\u0161\u00edch pot\u00ed\u017e\u00ed. Probl\u00e9mem \u00fadajn\u011b trp\u00ed p\u011bt procent sedmdes\u00e1tn\u00edk\u016f a 30 procent osmdes\u00e1tn\u00edk\u016f.<\/p>\n

V\u011bdci cht\u011bj\u00ed v projektu, kter\u00fd je pl\u00e1nov\u00e1n do roku 2019, ov\u011b\u0159it efektivitu a ekonomickou n\u00e1kladnost nov\u00e9ho l\u00e9\u010debn\u00e9ho postupu proti fyzick\u00e9 k\u0159ehkosti senior\u016f. V klinick\u00e9 studii se ve spolupr\u00e1ci s farmaceutick\u00fdm pr\u016fmyslem sna\u017e\u00ed identifikovat biomarkery pro rozezn\u00e1n\u00ed sarkopenie a pro monitorov\u00e1n\u00ed pr\u016fb\u011bhu a \u00fasp\u011b\u0161nosti l\u00e9\u010dby.<\/p>\n

„Ukazuje se, \u017ee stimulac\u00ed n\u011bkter\u00fdch receptor\u016f by mohlo doj\u00edt k r\u016fstu svalov\u00e9 hmoty a s\u00edly, co\u017e by bylo d\u016fle\u017eit\u00e9 pro pacienty na dial\u00fdze nebo po operaci kr\u010dku, kdy nemohou b\u00fdt fyzicky zat\u011b\u017eov\u00e1ni,“ \u0159ekla Topinkov\u00e1. Jako p\u0159\u00edklad l\u00e9\u010diva, kter\u00e9 je v sou\u010dasnosti v klinick\u00e9m testov\u00e1n\u00ed a mohlo by pomoct zabr\u00e1nit \u00faniku svalov\u00e9 hmoty, uvedla l\u00e1tku bimagrumab.<\/p>\n

Evropsk\u00e1 iniciativa IMI 2 po\u010d\u00edt\u00e1 do roku 2024 s rozd\u011blen\u00edm zhruba 3,23 miliardy eur, tedy asi 88 miliardy korun. Zapojuj\u00ed se do n\u00ed konsorcia slo\u017een\u00e1 z firem a akademick\u00fdch pracovi\u0161\u0165. \u010cesk\u00e1 akademick\u00e1 sf\u00e9ra v jej\u00edm r\u00e1mci zat\u00edm usp\u011bla jako \u010dlen mezin\u00e1rodn\u00edch konsorci\u00ed v celkem \u0161esti projektech. Podpo\u0159en\u00fd byl nap\u0159\u00edklad v\u00fdzkum zam\u011b\u0159en\u00fd na roztrou\u0161enou skler\u00f3zu, sta\u0159eckou k\u0159ehkost, revmatoidn\u00ed artritidu \u010di \u00fa\u010dinn\u011bj\u0161\u00ed o\u010dkov\u00e1n\u00ed proti \u010dern\u00e9mu ka\u0161li.<\/p>\n

Univerzita Karlova uzav\u0159ela loni v l\u00e9t\u011b memorandum o spolupr\u00e1ci s Asociac\u00ed inovativn\u00edho farmaceutick\u00e9ho pr\u016fmyslu (AIFP). Jej\u00ed rektor Tom\u00e1\u0161 Zima dnes tak\u00e9 zd\u016fraznil, \u017ee v\u00fdhody spolupr\u00e1ce jsou oboustrann\u00e9. Zat\u00edmco univerzita p\u0159isp\u00edv\u00e1 ke spolupr\u00e1ci nap\u0159\u00edklad absolventy, v\u00fdsledky v\u00fdzkumu \u010di unik\u00e1tn\u00edmi p\u0159\u00edstroji, z pr\u016fmyslov\u00e9 sf\u00e9ry na opl\u00e1tku z\u00edsk\u00e1v\u00e1 zak\u00e1zky na smluvn\u00ed v\u00fdzkum, mo\u017enost uplatn\u011bn\u00ed v\u00fdsledk\u016f sv\u00fdch projekt\u016f v praxi \u010di st\u00e1\u017ee pro sv\u00e9 studenty.<\/p>\n

AIFP sdru\u017euje 35 farmaceutick\u00fdch spole\u010dnost\u00ed, kter\u00e9 vyv\u00edjej\u00ed a uv\u00e1d\u011bj\u00ed na trh nov\u00e9, \u00fa\u010dinn\u011bj\u0161\u00ed a bezpe\u010dn\u011bj\u0161\u00ed p\u0159\u00edpravky. Je \u010dlenem Evropsk\u00e9 federace farmaceutick\u00fdch spole\u010dnost\u00ed.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00dabytku svalov\u00e9 hmoty a s\u00edly ve st\u00e1\u0159\u00ed by v budoucnu mohlo zabr\u00e1nit l\u00e9\u010divo, na jeho\u017e v\u00fdvoji se pod\u00edlej\u00ed v\u011bdci z Univerzity Karlovy ve spolupr\u00e1ci s […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":14531,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-27859","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27859","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27859"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27859\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/14531"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}