{"id":27913,"date":"2017-04-09T02:31:55","date_gmt":"2017-04-09T00:31:55","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=27913"},"modified":"2017-04-09T22:41:39","modified_gmt":"2017-04-09T20:41:39","slug":"nemoc-ktera-rozklada-kosti-zevnitr","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=27913","title":{"rendered":"Nemoc, kter\u00e1 rozkl\u00e1d\u00e1 kosti zevnit\u0159"},"content":{"rendered":"

Mnoho\u010detn\u00fd myelom\u00a0postihuje p\u0159edev\u0161\u00edm lidi star\u0161\u00ed 60 let.\u00a0 \u0160ance na vyl\u00e9\u010den\u00ed se sni\u017euje o to v\u00edce, \u017ee mnoz\u00ed pacienti zam\u011b\u0148uj\u00ed p\u0159\u00edznaky nemoci za b\u011b\u017en\u00e9 projevy pokro\u010dil\u00e9ho v\u011bku a l\u00e9ka\u0159skou pomoc vyhledaj\u00ed a\u017e p\u0159\u00edli\u0161 pozd\u011b.<\/strong><\/p>\n

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V kostech vznikaj\u00ed lo\u017eiska patrn\u00e1 na rentgenov\u00fdch sn\u00edmc\u00edch jako otvory. Samotn\u00e9 slovo myelom poch\u00e1z\u00ed z \u0159e\u010dtiny a znamen\u00e1 pr\u00e1v\u011b otvor v kosti.<\/p>\n

Bolest zad nemus\u00ed b\u00fdt jen o st\u00e1\u0159\u00ed<\/strong><\/p>\n

Doch\u00e1z\u00ed k \u00fabytku kostn\u00ed hmoty, kter\u00fd se snadno pozn\u00e1 na rentgenu viditeln\u00fdm \u201eprod\u011braven\u00edm\u201c kosti. Mezi prvn\u00ed p\u0159\u00edznaky onemocn\u011bn\u00ed pat\u0159\u00ed bolesti zad, p\u0159edev\u0161\u00edm v bedern\u00ed oblasti. V\u011bt\u0161ina nemocn\u00fdch je v\u0161ak pova\u017euje za b\u011b\u017en\u00e9 projevy st\u00e1rnut\u00ed a k doktorovi se odv\u00e1\u017e\u00ed, a\u017e kdy\u017e jsou bolesti nesnesiteln\u00e9 nebo dojde k samovoln\u00e9 zlomenin\u011b oslaben\u00e9 kosti. K t\u011bmto projev\u016fm se mohou p\u0159idat celkov\u00e1 slabost, \u00fanava, bledost a sn\u00ed\u017een\u00e1 imunita spojen\u00e1 s poruchou krvetvorby, kterou myelom m\u016f\u017ee vyvolat.<\/p>\n

\u201eZaveden\u00ed c\u00edlen\u00fdch l\u00e9k\u016f v l\u00e9\u010db\u011b MM znamen\u00e1 jeden z nejv\u00fdznamn\u011bj\u0161\u00edch pokrok\u016f v hematoonkologii za posledn\u00edch 15 let. U d\u0159\u00edve prognosticky velmi nep\u0159\u00edzniv\u00e9 malignity se p\u0159e\u017eit\u00ed pacient\u016f nejm\u00e9n\u011b dvojn\u00e1sobilo. Od sou\u010dasn\u00e9\u00a0 \u201evlny\u201c nov\u00fdch l\u00e9k\u016f se o\u010dek\u00e1v\u00e1, \u017ee myelom bude pat\u0159it mezi potenci\u00e1ln\u011b vyl\u00e9\u010diteln\u00e1 onemocn\u011bn\u00ed pro v\u00fdznamnou \u010d\u00e1st nemocn\u00fdch,\u201c uv\u00e1d\u00ed Prof. MUDr. Ivan \u0160pi\u010dka, CSc. z I. intern\u00ed kliniky 1LF UK a VFN v Praze.<\/p>\n

Nov\u00e1 nad\u011bje v l\u00e9\u010db\u011b<\/p>\n

V sou\u010dasn\u00e9 dob\u011b nen\u00ed mnoho\u010detn\u00fd myelom pln\u011b vyl\u00e9\u010diteln\u00e1 nemoc. I po \u00fasp\u011b\u0161n\u00e9 l\u00e9\u010db\u011b m\u00e1 onemocn\u011bn\u00ed sklony se vracet, mnoho pacient\u016f nep\u0159e\u017eije prvn\u00edch p\u011bt let od stanoven\u00ed diagn\u00f3zy. Tuto statistiku negativn\u011b ovliv\u0148uje pozdn\u00ed objeven\u00ed nemoci u pacienta. P\u0159esto lze s nemoc\u00ed bojovat, nemocn\u00e9mu d\u00e1t nad\u011bji na n\u011bkolik let \u017eivota a maxim\u00e1ln\u011b ho zkvalitnit. C\u00edlem l\u00e9\u010dby je sn\u00ed\u017eit po\u010det myelomov\u00fdch bun\u011bk tak, aby do\u0161lo k obnov\u011b tvorby kostn\u00ed tk\u00e1n\u011b a krve. K l\u00e9\u010db\u011b se jako u v\u011bt\u0161iny n\u00e1dorov\u00fdch onemocn\u011bn\u00ed pou\u017e\u00edv\u00e1 chemoterapie, kter\u00e1 likviduje rychle se mno\u017e\u00edc\u00ed bu\u0148ky. Chemoterapie dok\u00e1\u017ee prodlou\u017eit \u017eivot pacienta, v mnoha p\u0159\u00edpadech v\u0161ak vy\u017eaduje tak\u00e9 n\u00e1slednou transplantaci kostn\u00ed d\u0159en\u011b. Novou nad\u011bj\u00ed pro nemocn\u00e9 se st\u00e1v\u00e1 biologick\u00e1 l\u00e9\u010dba, kter\u00e1 byla loni registrov\u00e1na i v \u010cesk\u00e9 republice.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mnoho\u010detn\u00fd myelom\u00a0postihuje p\u0159edev\u0161\u00edm lidi star\u0161\u00ed 60 let.\u00a0 \u0160ance na vyl\u00e9\u010den\u00ed se sni\u017euje o to v\u00edce, \u017ee mnoz\u00ed pacienti zam\u011b\u0148uj\u00ed p\u0159\u00edznaky nemoci za b\u011b\u017en\u00e9 projevy pokro\u010dil\u00e9ho […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":27889,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-27913","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27913","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27913"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/27913\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/27889"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=27913"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=27913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}