{"id":29725,"date":"2017-12-06T10:56:40","date_gmt":"2017-12-06T09:56:40","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=29725"},"modified":"2017-12-06T10:56:40","modified_gmt":"2017-12-06T09:56:40","slug":"strevnich-zanetu-je-dnes-dvakrat-vice-nez-pred-30-lety","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=29725","title":{"rendered":"St\u0159evn\u00edch z\u00e1n\u011bt\u016f je dnes dvakr\u00e1t v\u00edce ne\u017e p\u0159ed 30 lety"},"content":{"rendered":"

Po\u010dty nemocn\u00fdch s nespecifick\u00fdmi st\u0159evn\u00edmi z\u00e1n\u011bty stoupaj\u00ed. Dnes je jich dvakr\u00e1t v\u00edce ne\u017e p\u0159ed 30 lety.<\/strong><\/p>\n

Ulcer\u00f3zn\u00ed kolitida i Crohnova choroba jsou dlouhodob\u011b trvaj\u00edc\u00ed onemocn\u011bn\u00ed, kter\u00e1 m\u00edvaj\u00ed st\u0159\u00eddav\u00fd pr\u016fb\u011bh. Obdob\u00ed klidu st\u0159\u00edd\u00e1 vysok\u00e1 aktivita, kdy se nemoc projevuje naplno. Proto m\u016f\u017ee trvat dlouho, ne\u017e je ur\u010dena diagn\u00f3za. \u201eProjevy jsou \u010dast\u00e9 pr\u016fjmy s p\u0159\u00edm\u011bs\u00ed krve, bolesti b\u0159icha a dal\u0161\u00ed komplikace. P\u0159\u00edznaky ale nemusej\u00ed b\u00fdt pouze st\u0159evn\u00ed. Symptomy mohou b\u00fdt mimo jin\u00e9 i bolesti kloub\u016f, ale tak\u00e9 afty nebo ko\u017en\u00ed vyr\u00e1\u017eky. U nespecifick\u00fdch st\u0159evn\u00edch z\u00e1n\u011bt\u016f nen\u00ed zcela jasn\u00e1 p\u0159\u00ed\u010dina vzniku. Svou roli zde hraje imunitn\u00ed reakce proti bu\u0148k\u00e1m tr\u00e1vic\u00edho syst\u00e9mu,\u201c uv\u00e1d\u00ed MUDr. Petr Podrou\u017eek, CSc., odborn\u00fd \u0159editel EUC Laborato\u0159\u00ed.<\/p>\n

Calprotectin pom\u00e1h\u00e1 st\u0159evn\u00ed z\u00e1n\u011bty rozli\u0161it<\/strong><\/p>\n

Calprotectin je protein, kter\u00fd je zji\u0161\u0165ov\u00e1n ve vy\u0161\u0161\u00ed koncentraci b\u011bhem st\u0159evn\u00edho z\u00e1n\u011btu, nap\u0159. p\u0159i ulcer\u00f3zn\u00ed kolitid\u011b, Crohnov\u011b chorob\u011b \u010di bakteri\u00e1ln\u00ed infekci za\u017e\u00edvac\u00edho traktu. B\u011b\u017en\u00e1 laboratorn\u00ed vy\u0161et\u0159en\u00ed z\u00e1n\u011btu v krvi nejsou specifick\u00e1 pro z\u00e1n\u011bty st\u0159ev, tak\u017ee stanoven\u00ed diagn\u00f3zy nen\u00ed pro l\u00e9ka\u0159e snadn\u00e9. Zv\u00fd\u0161en\u00e1 teplota, d\u00e9le trvaj\u00edc\u00ed pr\u016fjem a bolest v b\u0159i\u0161n\u00ed oblasti \u2013 to jsou spole\u010dn\u00e9 symptomy r\u016fzn\u00fdch onemocn\u011bn\u00ed, kter\u00e9 se li\u0161\u00ed p\u016fvodem i z\u00e1va\u017enost\u00ed.<\/p>\n

U funk\u010dn\u00edch poruch, jako je syndrom dr\u00e1\u017ediv\u00e9ho tra\u010dn\u00edku, a u celiakie (nesn\u00e1\u0161enlivosti lepku) jsou hladiny calprotectinu v norm\u00e1ln\u00edch mez\u00edch. \u201eVy\u0161et\u0159en\u00ed calprotectinu ve stolici p\u0159edstavuje jednoduch\u00fd neinvazivn\u00ed test, kter\u00fd u z\u00e1n\u011btliv\u00fdch poruch st\u0159eva m\u016f\u017ee pomoci vyhnout se diagnostick\u00e9 kolonoskopii. Vy\u0161et\u0159en\u00ed calprotectinu n\u00e1s m\u016f\u017ee upozornit na nemoc i v dob\u011b, kdy se zcela neprojevuje. Vy\u0161et\u0159en\u00ed n\u00e1m tak\u00e9 pom\u00e1h\u00e1 zjistit, zda se bl\u00ed\u017e\u00ed n\u00e1vrat onemocn\u011bn\u00ed, tzv. relaps. V\u010dasn\u00e1 l\u00e9\u010dba pak m\u016f\u017ee zabr\u00e1nit mo\u017en\u00fdm komplikac\u00edm a zajistit kvalitu \u017eivota,\u201c vysv\u011btluje MUDr. Petr Podrou\u017eek, CSc.<\/p>\n

Jak prob\u00edh\u00e1 vy\u0161et\u0159en\u00ed?<\/p>\n

Vy\u0161et\u0159en\u00ed je jednoduch\u00e9. Vzorek stolice o velikosti hr\u00e1\u0161ku odeberte do nesteriln\u00ed odb\u011brov\u00e9 n\u00e1dobky, kterou si m\u016f\u017eete vyzvednout ve v\u0161ech odb\u011brov\u00fdch centrech EUC Laborato\u0159\u00ed. Vzorek je stabiln\u00ed 6 dn\u016f p\u0159i teplot\u011b 4\u20138 \u00b0C a m\u016f\u017eete jej odevzdat v jak\u00e9mkoliv odb\u011brov\u00e9m centru EUC Laborato\u0159\u00ed \u2013 podrobn\u00fd seznam najdete na www.euclaboratore.cz. Nicm\u00e9n\u011b pozor \u2013 k dal\u0161\u00edm mo\u017en\u00fdm p\u0159\u00ed\u010din\u00e1m zv\u00fd\u0161en\u00ed calprotectinu ve stolici pat\u0159\u00ed i u\u017e\u00edv\u00e1n\u00ed salicyl\u00e1t\u016f a nesteroidn\u00edch l\u00e9k\u016f proti z\u00e1n\u011btu, je tedy nutn\u00e9 tuto p\u0159\u00ed\u010dinu vylou\u010dit.<\/p>\n

Ve\u0161ker\u00e1 vy\u0161et\u0159en\u00ed prov\u00e1d\u00edme i bez doporu\u010den\u00ed l\u00e9ka\u0159e za p\u0159\u00edmou \u00fahradu. <\/p>\n","protected":false},"excerpt":{"rendered":"

Po\u010dty nemocn\u00fdch s nespecifick\u00fdmi st\u0159evn\u00edmi z\u00e1n\u011bty stoupaj\u00ed. Dnes je jich dvakr\u00e1t v\u00edce ne\u017e p\u0159ed 30 lety.<\/p>\n<\/div>","protected":false},"author":1,"featured_media":29726,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-29725","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/29725","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=29725"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/29725\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/29726"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=29725"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=29725"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=29725"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}