{"id":33929,"date":"2020-03-10T14:04:48","date_gmt":"2020-03-10T13:04:48","guid":{"rendered":"http:\/\/www.invarena.cz\/?p=33929"},"modified":"2020-03-11T15:31:20","modified_gmt":"2020-03-11T14:31:20","slug":"u-novorozencu-patraji-po-nemoci-jez-v-dospelosti-zabiji","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=33929","title":{"rendered":"U novorozenc\u016f za\u010dali p\u00e1trat po nemoci, je\u017e v dosp\u011blosti zab\u00edj\u00ed"},"content":{"rendered":"\n

Desetitis\u00edci d\u011bt\u00ed odeberou l\u00e9ka\u0159i pupe\u010dn\u00edkovou krev, aby v\u010das zjistili, zda je ohro\u017euje nemoc, kter\u00e1 by je mohla u\u017e v\u00a0mlad\u00e9m v\u011bku st\u00e1t \u017eivot. Jde o famili\u00e1rn\u00ed hypercholesterolemii (FH) \u2013 t\u011blo si p\u0159i n\u00ed neporad\u00ed s\u00a0cholesterolem, jeho\u017e hladina v\u00a0krvi hroziv\u011b stoup\u00e1. Pokud \u010dlov\u011bk o nemoci nev\u00ed a nel\u00e9\u010d\u00ed se, m\u016f\u017ee u\u017e jako mlad\u00fd dostat infarkt nebo mozkovou mrtvici. V\u00a0\u010cesku m\u00e1 FH p\u0159ibli\u017en\u011b 40\u00a0000 lid\u00ed, ale jen asi p\u011btina z nich o sv\u00e9 diagn\u00f3ze v\u00ed. <\/strong><\/p>\n\n\n\n

Dvoulet\u00fd screening si klade za c\u00edl u 10\u00a0000 vy\u0161et\u0159en\u00fdch novorozenc\u016f ov\u011b\u0159it svoji efektivnost. P\u0159ipravuje ho \u010cesk\u00e1 spole\u010dnost pro ateroskler\u00f3zu (\u010cSAT) spole\u010dn\u011b s\u00a0N\u00e1rodn\u00edm screeningov\u00fdm centrem (NSC) \u00dastavu zdravotnick\u00fdch informac\u00ed a statistiky \u010cR (\u00daZIS \u010cR). Pokud se potvrd\u00ed p\u0159edpoklady, je velk\u00e1 \u0161ance, \u017ee se vy\u0161et\u0159en\u00ed vedouc\u00ed k\u00a0odhalen\u00ed FH stane sou\u010d\u00e1st\u00ed rutinn\u00edho screeningu u novorozenc\u016f. <\/p>\n\n\n\n

V\u00a0sou\u010dasnosti FH postihuje asi jedno z 250 d\u011bt\u00ed, celkem se tedy v\u00a0\u010cesku ro\u010dn\u011b narod\u00ed 400 nov\u00fdch pacient\u016f. Krom\u011b nemocn\u00fdch d\u011bt\u00ed odhal\u00ed screening chorobu i u jejich rodi\u010d\u016f, FH se toti\u017e p\u0159en\u00e1\u0161\u00ed v\u00a050 % p\u0159\u00edpad\u016f z\u00a0rodi\u010d\u016f na d\u011bti. <\/em><\/p>\n\n\n\n

\u201eP\u0159edpokl\u00e1d\u00e1me, \u017ee pilotn\u00ed projekt zachyt\u00ed 40 novorozenc\u016f s\u00a0FH, pokud se poda\u0159\u00ed vy\u0161et\u0159it dal\u0161\u00ed \u010dleny rodiny, mohl by cel\u00fd projekt v\u00e9st k\u00a0nalezen\u00ed a\u017e 120 nov\u00fdch pacient\u016f s\u00a0FH. P\u0159i zaveden\u00ed celoplo\u0161n\u00e9ho screeningu bychom p\u0159i 100 000 porodech ro\u010dn\u011b mohli zachytit a\u017e 1 200 lid\u00ed s\u00a0FH,\u201c<\/em> \u0159\u00edk\u00e1 p\u0159edseda \u010cSAT prof. MUDr. Michal Vrabl\u00edk, Ph.D. Podle n\u011bj je nejv\u011bt\u0161\u00ed riziko srde\u010dn\u011b-c\u00e9vn\u00edch komplikac\u00ed u lid\u00ed s\u00a0FH mo\u017en\u00e9 pozorovat mezi 25. a 39. rokem. <\/p>\n\n\n\n

\u201eRiziko srde\u010dn\u00edho infarktu je u p\u011btadvacetilet\u00e9ho nel\u00e9\u010den\u00e9ho pacienta s\u00a0FH a\u017e stokr\u00e1t vy\u0161\u0161\u00ed ne\u017e u zdrav\u00e9ho. Nel\u00e9\u010den\u00e1 FH vede k\u00a0ischemick\u00e9 chorob\u011b srde\u010dn\u00ed u 40 % osob mlad\u0161\u00edch 50 let,\u201c <\/em>dopl\u0148uje prof. Vrabl\u00edk. <\/p>\n\n\n\n

Zat\u00edmco lid\u00e9 s FH za hromad\u00edc\u00ed se cholesterol v\u00a0c\u00e9v\u00e1ch nemohou, v\u00a0\u010cesku \u017eij\u00ed miliony t\u011bch, kte\u0159\u00ed si sv\u00fdm \u017eivotn\u00edm stylem vysok\u00fd cholesterol \u201eh\u00fd\u010dkaj\u00ed\u201c. A velkou \u010d\u00e1st z\u00a0nich stoj\u00ed toto \u201eh\u00fd\u010dk\u00e1n\u00ed\u201c \u017eivot. <\/p>\n\n\n\n

V \u010cesku m\u00e1 zv\u00fd\u0161en\u00fd cholesterol a\u017e 80 % populace, pat\u0159\u00ed tak k nejrizikov\u011bj\u0161\u00edm zem\u00edm Evropy. Vysok\u00fd cholesterol vede k\u00a0ateroskler\u00f3ze, p\u0159i n\u00ed\u017e se tuk \u201elep\u00ed\u201c na st\u011bny tepen a ty se postupn\u011b uzav\u00edraj\u00ed. Pak hroz\u00ed srde\u010dn\u00ed infarkt \u010di mozkov\u00e1 mrtvice. <\/p>\n\n\n\n

Na komplikace ateroskler\u00f3zy podle prof. Vrabl\u00edka ro\u010dn\u011b zem\u0159e tolik osob, kolik je obyvatel Jihlavy, tedy kolem 50\u00a0000. Proto specialist\u00e9 na ateroskler\u00f3zu vedou proti vysok\u00e9mu cholesterolu l\u00edt\u00fd boj. <\/p>\n\n\n\n

Podle odborn\u00edk\u016f je naprost\u00fdm z\u00e1kladem zn\u00e1t sv\u00e9 hodnoty cholesterolu, a proto apeluj\u00ed na to, aby \u010ce\u0161i chodili na pravideln\u00e9 bezplatn\u00e9 preventivn\u00ed prohl\u00eddky k praktick\u00e9mu l\u00e9ka\u0159i. <\/p>\n\n\n\n

\u201ePr\u00e1v\u011b zde se mohou dozv\u011bd\u011bt, jak na tom se sv\u00fdm cholesterolem jsou, a mohou p\u0159\u00edpadn\u011b v\u010das zah\u00e1jit l\u00e9\u010debn\u00e1 opat\u0159en\u00ed. Proto\u017ee v\u0161ak \u010ce\u0161i prevenci moc nedaj\u00ed \u2013 na prohl\u00eddky jich chod\u00ed sotva polovina \u2013 sna\u017e\u00edme se naj\u00edt dal\u0161\u00ed mo\u017enosti, jak pov\u011bdom\u00ed o ateroskler\u00f3ze a jej\u00edch komplikac\u00edch zv\u00fd\u0161it,\u201c <\/em>vysv\u011btluje prof. Vrabl\u00edk. <\/p>\n\n\n\n

\u010cSAT se ve spolupr\u00e1ci s pacientskou organizac\u00ed Diagn\u00f3za FH, z.s., ka\u017edoro\u010dn\u011b sna\u017e\u00ed dohledat nemocn\u00e9 nap\u0159\u00edklad p\u0159i m\u011b\u0159en\u00ed ve spole\u010dnostech \u010di na \u00fa\u0159adech, kter\u00e9 se zapoj\u00ed do kampan\u011b.<\/p>\n\n\n\n

\u201eLoni jsme v takzvan\u00e9m T\u00fddnu FH zav\u00edtali nap\u0159\u00edklad do Poslaneck\u00e9 sn\u011bmovny a vy\u0161et\u0159ili 190 poslanc\u016f a zam\u011bstnanc\u016f sn\u011bmovny. Pr\u016fm\u011brn\u00fd lipidogram (tuky v\u00a0krvi) byl hor\u0161\u00ed ne\u017e kdekoli jinde. Do specializovan\u00e9ho centra jsme ihned poslali \u0161est z\u00a0nich. Oce\u0148ujeme ale jejich velk\u00fd z\u00e1jem o m\u011b\u0159en\u00ed a n\u00e1sledn\u00e9 konzultace,\u201c <\/em>popisuje Zde\u0148ka Cimick\u00e1, p\u0159edsedkyn\u011b organizace Diagn\u00f3za FH.<\/p>\n\n\n\n

Revoluci ve vn\u00edm\u00e1n\u00ed toho, jak\u00e1 by m\u011bla b\u00fdt spr\u00e1vn\u00e1 hladina \u201ezl\u00e9ho\u201c LDL cholesterolu v\u00a0krvi, p\u0159inesla nov\u011b zve\u0159ejn\u011bn\u00e1 evropsk\u00e1 doporu\u010den\u00ed. Odborn\u00edci se shodli, \u017ee \u010d\u00edm n\u00ed\u017ee, t\u00edm l\u00e9pe! <\/p>\n\n\n\n

\u201eNejnov\u011bj\u0161\u00ed v\u011bdeck\u00e1 pozn\u00e1n\u00ed jasn\u011b ukazuj\u00ed, \u017ee \u010d\u00edm je hladina cholesterolu v\u00a0krvi ni\u017e\u0161\u00ed, t\u00edm l\u00e9pe je \u010dlov\u011bk chr\u00e1n\u011bn proti ateroskler\u00f3ze a z\u00a0n\u00ed plynouc\u00edch rizik,\u201c<\/em> vysv\u011btluje prof. Vrabl\u00edk. Nejh\u016f\u0159e jsou na tom ku\u0159\u00e1ci, ob\u00e9zn\u00ed lid\u00e9, vystresovan\u00ed a star\u0161\u00ed 55 let. Hromad\u00edc\u00ed se cholesterol je z\u00e1ke\u0159n\u00fd v\u00a0tom, \u017ee nebol\u00ed \u2013 lid\u00e9 o n\u011bm proto \u010dasto nev\u011bd\u00ed. Ti, kte\u0159\u00ed jsou si vysok\u00e9ho cholesterolu v\u011bdomi, zase bojuj\u00ed s\u00a0takzvanou adherenc\u00ed k\u00a0l\u00e9\u010db\u011b, tedy aby spr\u00e1vn\u011b u\u017e\u00edvali l\u00e9ky a dodr\u017eovali z\u00e1sady t\u00fdkaj\u00edc\u00ed se stravy a pohybu. <\/p>\n\n\n\n

Z\u00a0pr\u016fzkum\u016f spole\u010dnost\u00ed Ipsos a IQVIA, kter\u00e9 iniciovala spole\u010dnost Teva Pharmaceuticals CR, vyplynulo, \u017ee nejv\u011bt\u0161\u00edmi \u201eh\u0159\u00ed\u0161n\u00edky\u201c, co se dodr\u017eov\u00e1n\u00ed l\u00e9\u010dby t\u00fd\u010de, jsou pr\u00e1v\u011b lid\u00e9 s\u00a0chronick\u00fdmi nemocemi, je\u017e nebol\u00ed, ale pacientovi to \u201espo\u010d\u00edtaj\u00ed\u201c pozd\u011bji.<\/p>\n\n\n\n

\u201ePouze 39 % pacient\u016f s\u00a0vysokou hladinou tuk\u016f v krvi v dotazn\u00edku spole\u010dnosti IQVIA uvedlo, \u017ee za posledn\u00edch \u0161est m\u011bs\u00edc\u016f v\u017edy u\u017e\u00edvalo l\u00e9ky podle doporu\u010den\u00ed l\u00e9ka\u0159e. Odborn\u00e9 studie uk\u00e1zaly, \u017ee i\u00a0lid\u00e9, kte\u0159\u00ed prod\u011blali infarkt, stejn\u011b do dvou let p\u0159estali v 50 % br\u00e1t l\u00e9ky tak, jak by m\u011bli. U t\u011bchto pacient\u016f je pak riziko op\u011btovn\u00e9 p\u0159\u00edhody o 50\u201380 % vy\u0161\u0161\u00ed,\u201c <\/em>cituje prof. Vrabl\u00edk s\u00a0t\u00edm, \u017ee s dodr\u017eov\u00e1n\u00edm l\u00e9\u010dby m\u00edvaj\u00ed probl\u00e9m pr\u00e1v\u011b mlad\u00ed lid\u00e9, kte\u0159\u00ed nemoc odm\u00edtaj\u00ed. \u201eU\u00a0mlad\u0161\u00edho pacienta je a\u017e 2,5\u00d7 vy\u0161\u0161\u00ed riziko, \u017ee p\u0159estane u\u017e\u00edvat l\u00e9\u010dbu, ve srovn\u00e1n\u00ed s pacienty po pades\u00e1tce,\u201c<\/em> dod\u00e1v\u00e1. <\/p>\n\n\n\n

redakce invArena<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Desetitis\u00edci d\u011bt\u00ed odeberou l\u00e9ka\u0159i pupe\u010dn\u00edkovou krev, aby v\u010das zjistili, zda je ohro\u017euje nemoc, kter\u00e1 by je mohla u\u017e v\u00a0mlad\u00e9m v\u011bku st\u00e1t \u017eivot. Jde o famili\u00e1rn\u00ed […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":23617,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,9],"tags":[],"class_list":["post-33929","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/33929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=33929"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/33929\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/23617"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=33929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=33929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=33929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}