Praha, 29. 9. 2020 \u2013 Testovat l\u00e9ky na bu\u0148k\u00e1ch, kter\u00e9 se podobaj\u00ed mozkov\u00fdm, se u\u010d\u00ed l\u00e9ka\u0159i v ned\u00e1vno vznikl\u00e9m Epileptologick\u00e9m v\u00fdzkumn\u00e9m centru (EpiReC) sdru\u017euj\u00edc\u00edm \u0161pi\u010dkov\u00e9 odborn\u00edky z FN Motol, Univerzity Karlovy, Akademie v\u011bd a \u010cesk\u00e9ho vysok\u00e9ho u\u010den\u00ed technick\u00e9ho (\u010cV\u00daT). Bu\u0148ky um\u00ed vyp\u011bstovat z krve konkr\u00e9tn\u00edho pacienta. Nov\u00e9 cesty v l\u00e9\u010db\u011b uv\u00edtaj\u00ed des\u00edtky tis\u00edc nositel\u016f tohoto neurologick\u00e9ho onemocn\u011bn\u00ed, kter\u00e9 se historicky nevyhnulo ani Dostojevsk\u00e9mu nebo c\u00edsa\u0159i Caligulovi. Nemoc ka\u017edoro\u010dn\u011b p\u0159ipom\u00edn\u00e1 N\u00e1rodn\u00ed den epilepsie, kter\u00fd p\u0159ipad\u00e1 na 30. z\u00e1\u0159\u00ed. Posledn\u00edho z\u00e1\u0159\u00ed tak\u00e9 kon\u010d\u00ed v\u00fdtvarn\u00e1 sout\u011b\u017e pro d\u011bti s epilepsi\u00ed \u201eL\u00edb\u00ed se ti, mami?\u201c, kter\u00e1 pom\u00e1h\u00e1 \u0161\u00ed\u0159it osv\u011btu a usiluje o zlep\u0161en\u00ed \u017eivota d\u011btsk\u00fdch pacient\u016f. Sout\u011b\u017e pro d\u011bti zaji\u0161\u0165uje spolek EpiStop. <\/p>\n\n\n\n
\u201eTouto ojedin\u011blou sout\u011b\u017e\u00ed chceme zm\u00edrnit ka\u017edodenn\u00ed obavy a starosti rodi\u010d\u016f d\u011bt\u00ed s epilepsi\u00ed. Sna\u017e\u00edme se o destigmatizaci nemoci a \u0161\u00ed\u0159en\u00ed pov\u011bdom\u00ed o poskytov\u00e1n\u00ed prvn\u00ed pomoci p\u0159i epileptick\u00fdch z\u00e1chvatech. T\u00e9matem leto\u0161n\u00edho ro\u010dn\u00edku v\u00fdtvarn\u00e9 sout\u011b\u017ee je \u201aM\u016fj nejv\u011bt\u0161\u00ed sen\u2018\u200e. V\u00fdherce sout\u011b\u017ee vyhl\u00e1s\u00edme za\u010d\u00e1tkem \u0159\u00edjna,\u201c \u0159\u00edk\u00e1 za organiz\u00e1tory sout\u011b\u017ee Monika B\u00e1rtov\u00e1. Lid\u00e9 s epilepsi\u00ed \u010dasto kv\u016fli nepochopen\u00ed a p\u0159edsudk\u016fm z okol\u00ed svou nemoc p\u0159ed ostatn\u00edmi skr\u00fdvaj\u00ed. Epilepsi\u00ed p\u0159itom v \u010cesk\u00e9 republice trp\u00ed p\u0159ibli\u017en\u011b 80 tis\u00edc lid\u00ed. \u010ctvrtinu z nich tvo\u0159\u00ed pr\u00e1v\u011b d\u011bti, u kter\u00fdch jde o jedno z nej\u010dast\u011bj\u0161\u00edch chronick\u00fdch onemocn\u011bn\u00ed. Epilepsie z\u00e1sadn\u011b ovliv\u0148uje \u017eivot v\u011bt\u0161in\u011b pacient\u016f. L\u00e9\u010dba se neust\u00e1le vyv\u00edj\u00ed tak, aby mohli lid\u00e9 s epilepsi\u00ed \u017e\u00edt plnohodnotn\u00fd \u017eivot. <\/p>\n\n\n\n
\u201ePot\u00fdkali jsme se s t\u00edm, \u017ee p\u0159\u00edli\u0161 dlouho trvalo, ne\u017e se poda\u0159ilo vyzkouman\u00e9 poznatky dostat do praxe p\u0159\u00edmo k pacient\u016fm. Snahou v\u00fdzkumn\u00e9ho centra je, aby se pacienti mohli \u00fa\u010dastnit p\u0159\u00edmo klinick\u00e9ho v\u00fdzkumu,\u201c \u0159\u00edk\u00e1 MUDr. Jana Z\u00e1rubov\u00e1 z Centra pro epilepsie FN Motol, kter\u00e1 je z\u00e1rove\u0148 m\u00edstop\u0159edsedkyn\u00ed spolku EpiStop, a dod\u00e1v\u00e1: \u201eNov\u011b experimentujeme s t\u00edm, jak v laboratorn\u00edch podm\u00ednk\u00e1ch z krve vyp\u011bstovat bu\u0148ky \u010dlov\u011bka, kter\u00e9 odpov\u00eddaj\u00ed jeho mozkov\u00fdm bu\u0148k\u00e1m. Na t\u011bch bychom pot\u00e9 mohli testovat \u00fa\u010dinnost l\u00e9k\u016f je\u0161t\u011b p\u0159ed t\u00edm, ne\u017e je d\u00e1me pacientovi.\u201c Specialist\u00e9 nov\u011b spolupracuj\u00ed se zahrani\u010dn\u00edmi laborato\u0159emi, aby mohli lidi s epilepsi\u00ed p\u0159esn\u011bji diagnostikovat. Vyu\u017e\u00edvaj\u00ed to nap\u0159\u00edklad u pacient\u016f, kte\u0159\u00ed maj\u00ed sou\u010dasn\u011b epilepsii i ment\u00e1ln\u00ed retardaci. \u201eNev\u011bd\u011bli jsme, pro\u010d maj\u00ed pacienti tyto diagn\u00f3zy sou\u010dasn\u011b. Zahrani\u010dn\u00ed v\u011bdci zjistili, \u017ee jde o mutaci tzv. sod\u00edkov\u00e9ho kan\u00e1lu a my t\u00edm p\u00e1dem m\u016f\u017eeme pacienta u\u0161et\u0159it dal\u0161\u00edho kola rozs\u00e1hl\u00fdch vy\u0161et\u0159en\u00ed. Opravdu se bl\u00ed\u017e\u00edme k personalizovan\u00e9 medic\u00edn\u011b, kter\u00e1 je pacient\u016fm u\u0161it\u00e1 p\u0159\u00edmo na m\u00edru,\u201c\u200e vysv\u011btluje MUDr. Z\u00e1rubov\u00e1. <\/p>\n\n\n\n
O epilepsii<\/p>\n\n\n\n
Epilepsie je neurologick\u00e9 onemocn\u011bn\u00ed charakterizovan\u00e9 opakovan\u00fdm v\u00fdskytem neprovokovan\u00fdch epileptick\u00fdch z\u00e1chvat\u016f. Pat\u0159\u00ed mezi nej\u010dast\u011bj\u0161\u00ed mozkov\u00e1 onemocn\u011bn\u00ed. Ke stanoven\u00ed diagn\u00f3zy epilepsie zpravidla doch\u00e1z\u00ed p\u0159i v\u00fdskytu dvou a v\u00edce epileptick\u00fdch z\u00e1chvat\u016f, v\u00fdjime\u010dn\u011b ji\u017e po jednom takov\u00e9m z\u00e1chvatu. Epilepsie nen\u00ed jedna nemoc, jedn\u00e1 se sp\u00ed\u0161e o skupinu onemocn\u011bn\u00ed. Hlavn\u00edm projevem jsou epileptick\u00e9 z\u00e1chvaty, kter\u00e9 mohou m\u00edt r\u016fznou podobu. Mohou se projevovat nap\u0159. pouh\u00fdm zahled\u011bn\u00edm, brn\u011bn\u00edm kon\u010detin, v\u00fdpadkem pam\u011bti nebo zn\u00e1m\u00fdmi k\u0159e\u010demi kon\u010detin se ztr\u00e1tou v\u011bdom\u00ed. Vyskytuj\u00ed se jak v pr\u016fb\u011bhu dne, tak v noci b\u011bhem sp\u00e1nku. P\u0159esto\u017ee se epilepsie m\u016f\u017ee objevit v kter\u00e9mkoli v\u011bku, jsou \u017eivotn\u00ed obdob\u00ed, ve kter\u00fdch je nov\u00fd v\u00fdskyt epileptick\u00fdch z\u00e1chvat\u016f \u010dast\u011bj\u0161\u00ed ne\u017e v jin\u00fdch \u2013 hlavn\u00ed vrcholy jsou u mal\u00fdch d\u011bt\u00ed a v obdob\u00ed st\u00e1\u0159\u00ed. P\u0159\u00ed\u010diny mohou b\u00fdt z\u00edskan\u00e9 na podklad\u011b \u00farazu, infekce, vrozen\u00fdch odchylek v\u00fdvoje mozku \u010di na genetick\u00e9m podklad\u011b. U p\u0159ev\u00e1\u017en\u00e9 v\u011bt\u0161iny epilepsi\u00ed nen\u00ed p\u0159\u00ed\u010dina doposud zn\u00e1ma. Epilepsii m\u00e1 v \u010cesk\u00e9 republice p\u0159ibli\u017en\u011b 80 000 lid\u00ed. V sou\u010dasn\u00e9 dob\u011b l\u00e9ka\u0159i p\u0159i spr\u00e1vn\u00e9 a v\u010dasn\u00e9 diagnostice a farmakologick\u00e9 l\u00e9\u010db\u011b dostanou nemoc pod kontrolu a\u017e u 70 % pacient\u016f. Celosv\u011btov\u011b m\u00e1 epilepsii v\u00edce ne\u017e 50 milion\u016f lid\u00ed, v Evrop\u011b p\u0159es 6 milion\u016f lid\u00ed, z toho p\u0159ibli\u017en\u011b 2 miliony d\u011bt\u00ed.<\/p>\n\n\n\n
Tiskov\u00e1 zpr\u00e1va<\/p>\n","protected":false},"excerpt":{"rendered":"
Praha, 29. 9. 2020 \u2013 Testovat l\u00e9ky na bu\u0148k\u00e1ch, kter\u00e9 se podobaj\u00ed mozkov\u00fdm, se u\u010d\u00ed l\u00e9ka\u0159i v ned\u00e1vno vznikl\u00e9m Epileptologick\u00e9m v\u00fdzkumn\u00e9m centru (EpiReC) sdru\u017euj\u00edc\u00edm \u0161pi\u010dkov\u00e9 […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":1875,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-35050","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/35050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=35050"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/35050\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/1875"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=35050"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=35050"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=35050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}