Metoda transkrani\u00e1ln\u00ed magnetick\u00e9 stimulace, tedy ovlivn\u011bn\u00ed elektromagnetick\u00fdmi impulzy, je zaveden\u00e1 p\u0159i l\u00e9\u010db\u011b deprese. Nyn\u00ed se \u010de\u0161t\u00ed a n\u011bme\u010dt\u00ed l\u00e9ka\u0159i sna\u017e\u00ed prok\u00e1zat jej\u00ed \u00fa\u010dinky i p\u0159i l\u00e9\u010db\u011b schizofrenie. I d\u00edl\u010d\u00ed \u00fasp\u011bch by podle autor\u016f v\u00fdzkumu mohl znamenat zlep\u0161en\u00ed \u017eivota pacient\u016f, kte\u0159\u00ed t\u00edmto onemocn\u011bn\u00edm trp\u00ed.
Postihnout m\u016f\u017ee kohokoli. Statisticky pak zas\u00e1hne jednoho \u010dlov\u011bka ze sta, nej\u010dast\u011bji ve v\u011bku od 18 do 30 let.
Schizofrenie je v\u00e1\u017en\u00fdm du\u0161evn\u00edm onemocn\u011bn\u00edm a rozvinout se m\u016f\u017ee u\u017e b\u011bhem dosp\u00edv\u00e1n\u00ed.
Je to nemoc, kterou lze asi u t\u0159etiny nemocn\u00fdch vyl\u00e9\u010dit. Zbyl\u00ed pacienti se ale bohu\u017eel s p\u0159\u00edznaky pot\u00fdkaj\u00ed do\u017eivotn\u011b a musej\u00ed u\u017e\u00edvat l\u00e9ky.
V posledn\u00edch letech ale v\u011bdci zkoumaj\u00ed, zda by bylo mo\u017en\u00e9 n\u011bkter\u00e9 z p\u0159\u00edznak\u016f schizofrenie ovlivnit elektromagnetick\u00fdmi impulzy, takzvanou „metodou transkrani\u00e1ln\u00ed magnetick\u00e9 stimulace“. Ta je bezbolestn\u00e1 a v praxi u\u017e je asi 15 let uznanou terapi\u00ed p\u0159i l\u00e9\u010db\u011b deprese. U schizofrenie se ale v\u00fdsledky dosavadn\u00edch studi\u00ed rozch\u00e1zej\u00ed.
52 662 – Pacienti se schizofreni\u00ed v roce 2015.
\u010ce\u0161t\u00ed l\u00e9ka\u0159i z Brna a Ostravy proto zah\u00e1jili spolupr\u00e1ci se dv\u011bma v\u00fdzkumn\u00fdmi centry v N\u011bmecku.
Spustili mezin\u00e1rodn\u00ed studii, kter\u00e1 m\u00e1 ambici potvrdit \u010di vyvr\u00e1tit \u00fa\u010dinnost t\u00e9to metody v l\u00e9\u010db\u011b schizofrenie. Nav\u00edc cht\u011bj\u00ed zmapovat, zda doch\u00e1z\u00ed k viditeln\u00fdm, tedy zobraziteln\u00fdm zm\u011bn\u00e1m v aktivit\u011b mozku.
„Pokud se poda\u0159\u00ed prok\u00e1zat \u00fa\u010dinnost alespo\u0148 jednoho z protokol\u016f (\u010d\u00e1st\u00ed v\u00fdzkumu), mohlo by to znamenat nad\u011bji na zlep\u0161en\u00ed kvality \u017eivota p\u0159inejmen\u0161\u00edm \u010d\u00e1sti pacient\u016f trp\u00edc\u00edch schizofreni\u00ed,“ \u0159\u00edk\u00e1 p\u0159edseda Sekce biologick\u00e9 psychiatrie Psychiatrick\u00e9 spole\u010dnosti \u010cLS JEP Libor Ustohal. Ten je jedn\u00edm z autor\u016f v\u00fdzkumu. Jako nad\u011bjn\u00e1 se tato \u0161etrn\u00e1 metoda jev\u00ed hlavn\u011b p\u0159i ovlivn\u011bn\u00ed takzvan\u00fdch negativn\u00edch p\u0159\u00edznak\u016f. Negativn\u00edm p\u0159\u00edznakem je t\u0159eba oplo\u0161t\u011bn\u00ed emoc\u00ed. Nemocn\u00fd nen\u00ed schopen pro\u017e\u00edvat pozitivn\u00ed ani negativn\u00ed emoce. \u0158ad\u00ed se k nim ale i takzvan\u00e1 abulie, kdy se lid\u00e9 nedok\u00e1\u017eou p\u0159im\u011bt k \u017e\u00e1dn\u00e9 aktivit\u011b.
54 479 – Pacienti se schizofreni\u00ed v roce 2017.
„Maj\u00ed probl\u00e9m vst\u00e1t v\u016fbec z postele, ud\u011blat b\u011b\u017enou hygienu, nato\u017e j\u00edt do pr\u00e1ce a tam vykon\u00e1vat po n\u011bjakou dobu soust\u0159ed\u011bn\u00fd v\u00fdkon. Je to ale i soci\u00e1ln\u00ed sta\u017een\u00ed, kdy nemaj\u00ed z\u00e1jem o okoln\u00ed prost\u0159ed\u00ed. Nejsou pak schopni pracovat a jsou odk\u00e1z\u00e1ni na invalidn\u00ed d\u016fchod,“ vysv\u011btluje d\u016fsledky Ustohal. Oproti tomu takzvan\u00e9 pozitivn\u00ed p\u0159\u00edznaky schizofrenie jako bludy \u010di halucinace se v\u011bt\u0161inou objevuj\u00ed v epizod\u00e1ch. Daj\u00ed se proto zvl\u00e1dnout l\u00e9ky, tak\u017ee lid\u00e9 v obdob\u00ed bez p\u0159\u00edznak\u016f funguj\u00ed docela norm\u00e1ln\u011b.<\/p>\n\n\n\n
„\u0164uk\u00e1n\u00ed“ na hlavu Metoda transkrani\u00e1ln\u00ed magnetick\u00e9 stimulace, tedy ovlivn\u011bn\u00ed elektromagnetick\u00fdmi impulzy, je zaveden\u00e1 p\u0159i l\u00e9\u010db\u011b deprese. Nyn\u00ed se \u010de\u0161t\u00ed a n\u011bme\u010dt\u00ed l\u00e9ka\u0159i sna\u017e\u00ed prok\u00e1zat jej\u00ed \u00fa\u010dinky i p\u0159i […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":13918,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-35259","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/35259","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=35259"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/35259\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/13918"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=35259"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=35259"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=35259"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
Impulzem l\u00e9ka\u0159\u016fm k zah\u00e1jen\u00ed prvn\u00ed mezin\u00e1rodn\u00ed studie v t\u00e9to oblasti byly nejezdnozna\u010dn\u00e9 v\u00fdsledky zkoum\u00e1n\u00ed z p\u0159edchoz\u00edch let. Jejich z\u00e1v\u011bry se toti\u017e rozch\u00e1zej\u00ed. Te\u010f proto cht\u011bj\u00ed l\u00e9ka\u0159i ud\u011blat opravdu komplexn\u00ed studii.
„Jde o to, \u017ee u TMS z\u00e1le\u017e\u00ed na nastaven\u00ed \u0159ady parametr\u016f. De facto studie, kter\u00e9 byly publikovan\u00e9, tak t\u00e9m\u011b\u0159 ka\u017ed\u00e1 m\u011bla trochu jin\u00e9 parametry, tak\u017ee jsou obt\u00ed\u017en\u011b porovnateln\u00e9,“ vysv\u011btluje Ustohal.
54 687 – Pacienti se schizofreni\u00ed v roce 2019.
\u010cesko-n\u011bmeck\u00e1 studie je proto rozd\u011blen\u00e1 do t\u0159\u00ed f\u00e1z\u00ed. Prvn\u00ed dv\u011b pracuj\u00ed s rozd\u00edln\u00fdm nastaven\u00edm frekvence stimulace. T\u0159et\u00ed je kontroln\u00ed neboli placebov\u00e1. Kontrola pomoc\u00ed placeba se uplat\u0148uje u v\u0161ech medic\u00ednsk\u00fdch v\u00fdzkum\u016f. „Pl\u00e1nujeme minim\u00e1ln\u011b pades\u00e1t pacient\u016f, ve v\u0161ech centrech dohromady sto pacient\u016f,“ dopl\u0148uje Ustohal.
Metoda TMS, kter\u00e1 vyu\u017e\u00edv\u00e1 magnetick\u00e9 pole ke stimulaci nervov\u00fdch bun\u011bk v mozku, je bezbolestn\u00e1 a nen\u00ed nep\u0159\u00edjemn\u00e1.
\u010ce\u0161i p\u0159i epidemii kupovali v\u00edc l\u00e9k\u016f na schizofrenii a m\u00e9n\u011b na \u00fazkost
Pacient p\u0159i terapii sed\u00ed v k\u0159esle, je p\u0159i v\u011bdom\u00ed a nepod\u00e1vaj\u00ed se mu p\u0159edt\u00edm \u017e\u00e1dn\u00e9 l\u00e9ky. L\u00e9ka\u0159 mu k hlav\u011b p\u0159ilo\u017e\u00ed stimula\u010dn\u00ed c\u00edvku, kter\u00e1 se zam\u011b\u0159uje na konkr\u00e9tn\u00ed oblast, kter\u00e1 se m\u00e1 stimulovat. „Jakmile se c\u00edvka p\u0159ilo\u017e\u00ed, spust\u00ed se stimulace a pacient poci\u0165uje jemn\u00e9 \u0165uk\u00e1n\u00ed do hlavy. To jsou ony jednotliv\u00e9 elektromagnetick\u00e9 pulzy. Ty se opakuj\u00ed b\u011bhem stimulace mnohokr\u00e1t,“ popisuje Ustohal.
Metoda TMS se stimulac\u00ed nervov\u00fdch bun\u011bk se zkou\u0161\u00ed i v terapii obsedantn\u011b-kompulzivn\u00ed poruchy (\u00fazkostn\u00e9 onemocn\u011bn\u00ed), n\u011bkter\u00fdch n\u00e1vykov\u00fdch poruch \u010di posttraumatick\u00e9 stresov\u00e9 poruchy.
https:\/\/www.idnes.cz\/zpravy\/domaci\/schizofrenie-lecba-elektromagneticke-impulzy.A201104_194136_domaci_mama<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"