Nejnov\u011bj\u0161\u00ed v\u011bdeck\u00e1 studie zjistila, \u017ee nov\u00e1 l\u00e9\u010dba rakoviny pomoc\u00ed LED z\u00e1\u0159en\u00ed by mohla b\u00fdt \u00fa\u010dinn\u011bj\u0161\u00ed ne\u017e sou\u010dasn\u00e9 modern\u00ed imunoterapie.<\/p>\n\n\n\n
V\u011bdci z\u00a0V\u00fdchodoanglick\u00e9 univerzity zve\u0159ejnili v\u00a0\u010dasopise Nature Chemical Biology studii o\u00a0l\u00e9\u010db\u011b rakoviny, kter\u00e1 vypad\u00e1 jako vytr\u017een\u00e1 ze science fiction. P\u0159itom by brzy mohla b\u00fdt b\u011b\u017enou skute\u010dnost\u00ed. Fungovat m\u00e1 tak, \u017ee se v\u00a0bl\u00edzkosti n\u00e1doru rozsv\u00edt\u00ed LED sv\u011btla, kter\u00e1 n\u00e1sledn\u011b aktivuj\u00ed bioterapeutick\u00fd l\u00e9k. Podle expert\u016f se jedn\u00e1 o\u00a0vysoce c\u00edlenou metodu s\u00a0je\u0161t\u011b vy\u0161\u0161\u00ed \u00fa\u010dinnost\u00ed, ne\u017e m\u00e1 sou\u010dasn\u00e1 nejmodern\u011bj\u0161\u00ed imunoterapie. Z\u00e1rove\u0148 by mohla v\u00fdrazn\u011b sn\u00ed\u017eit mno\u017estv\u00ed toxin\u016f v\u00a0t\u011ble.<\/p>\n\n\n\n
P\u0159esn\u00e1 l\u00e9\u010dba rakoviny<\/p>\n\n\n\n
Sou\u010dasn\u00e1 l\u00e9\u010dba rakoviny, jako je chemoterapie, ni\u010d\u00ed rakovinn\u00e9 bu\u0148ky, ale z\u00e1rove\u0148 m\u016f\u017ee po\u0161kozovat bu\u0148ky zdrav\u00e9. \u201eDosud vzniklo n\u011bkolik protil\u00e1tek, kter\u00e9 se v\u00e1\u017eou na povrchy rakovinn\u00fdch bun\u011bk. Ty n\u00e1sledn\u011b dod\u00e1vaj\u00ed cytotoxick\u00e9 l\u00e9ky a ozna\u010duj\u00ed m\u00edsta ur\u010den\u00e1 ke zni\u010den\u00ed imunitn\u00edm syst\u00e9mem,\u201c vysv\u011btlil docent chemick\u00e9 fakulty na V\u00fdchodoanglick\u00e9 univerzit\u011b a vedouc\u00ed studie Amia Sachdev odborn\u00e9mu serveru Healthline.<\/p>\n\n\n\n
Dodal, \u017ee dosavadn\u00ed protil\u00e1tky se sice pod\u00e1vaj\u00ed jako c\u00edlen\u00e1 l\u00e9\u010diva, ale receptory na povrchu napaden\u00fdch bun\u011bk jsou stejn\u00e9 jako u zdrav\u00fdch, a proto doch\u00e1z\u00ed i k vedlej\u0161\u00edm \u00fa\u010dink\u016fm.<\/p>\n\n\n\n
Podle Sachdeva se v\u0161ak jeho t\u00fdmu poda\u0159ilo tento probl\u00e9m vy\u0159e\u0161it. Vyvinul fragmenty protil\u00e1tek, kter\u00e9 vytv\u00e1\u0159ej\u00ed vazbu s c\u00edlov\u00fdmi receptory po oz\u00e1\u0159en\u00ed LED sv\u011btlem o specifick\u00e9 vlnov\u00e9 d\u00e9lce. \u201eT\u00edm se zajist\u00ed aktivace l\u00e9ku na konkr\u00e9tn\u00edm m\u00edst\u011b, ani\u017e by se ohrozilo jeho okol\u00ed,\u201c popsal v\u011bdec. \u201eTak\u00e9 by to mohlo znamenat, \u017ee protil\u00e1tky trvale p\u0159ilnou ke sv\u00e9mu c\u00edli,\u201c dodal.<\/p>\n\n\n\n
V praxi by l\u00e9\u010dba m\u011bla prob\u00edhat tak, \u017ee t\u0159eba v p\u0159\u00edpad\u011b rakoviny k\u016f\u017ee se sv\u011btlo zven\u010d\u00ed zam\u00ed\u0159\u00ed p\u0159\u00edmo na posti\u017een\u00e9 m\u00edsto a t\u00edm aktivuje bioterapeutick\u00e9 l\u00e9ky podan\u00e9 pacientovi. Pokud by se jednalo o n\u00e1dor vnit\u0159n\u00edch org\u00e1n\u016f, k \u00fa\u010delu poslou\u017e\u00ed mal\u00e1 LED sv\u011btla implantovan\u00e1 v m\u00edst\u011b rakoviny.<\/p>\n\n\n\n
\u201e\u0158ekl bych, \u017ee se jedn\u00e1 o zaj\u00edmavou strategii, je\u017e m\u016f\u017ee potenci\u00e1ln\u011b zlep\u0161it hromad\u011bn\u00ed l\u00e9\u010diva a jeho v\u00fddr\u017e v m\u00edst\u011b n\u00e1doru,\u201c vyj\u00e1d\u0159il se pro Healthline Piotr Grodzinski z Nanodelivery Systems and Devices Branch, kter\u00fd se na studii nepod\u00edlel.<\/p>\n\n\n\n
Budoucnost na dosah<\/p>\n\n\n\n
Sachdev podotkl, \u017ee tato metoda by se mohla pou\u017e\u00edvat k l\u00e9\u010db\u011b lokalizovan\u00fdch n\u00e1dor\u016f nebo rakoviny k\u016f\u017ee, ale ne pro rakoviny krve, jako je nap\u0159\u00edklad leuk\u00e9mie. \u201eDouf\u00e1me, \u017ee na\u0161e pr\u00e1ce povede k v\u00fdvoji nov\u00e9 t\u0159\u00eddy vysoce c\u00edlen\u00fdch bioterapeutik reaguj\u00edc\u00edch na sv\u011btlo,\u201c pov\u011bd\u011bl pro The Independent.<\/p>\n\n\n\n
Pokud budou v\u011bdci v dal\u0161\u00edch f\u00e1z\u00edch sv\u00e9 pr\u00e1ce \u00fasp\u011b\u0161n\u00ed, doufaj\u00ed, \u017ee se nov\u00e1 generace imunoterapie bude k l\u00e9\u010db\u011b pacient\u016f s rakovinou pou\u017e\u00edvat do p\u011bti a\u017e deseti let.<\/p>\n\n\n\n
Tom\u00e1\u0161 Rosa<\/p>\n\n\n\n
Den\u00edk.cz<\/p>\n\n\n\n
https:\/\/www.denik.cz\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":" Nejnov\u011bj\u0161\u00ed v\u011bdeck\u00e1 studie zjistila, \u017ee nov\u00e1 l\u00e9\u010dba rakoviny pomoc\u00ed LED z\u00e1\u0159en\u00ed by mohla b\u00fdt \u00fa\u010dinn\u011bj\u0161\u00ed ne\u017e sou\u010dasn\u00e9 modern\u00ed imunoterapie. V\u011bdci z\u00a0V\u00fdchodoanglick\u00e9 univerzity zve\u0159ejnili v\u00a0\u010dasopise Nature […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":24987,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-38572","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/38572","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38572"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/38572\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/24987"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38572"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=38572"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=38572"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}