Rakovina krve zauj\u00edm\u00e1 v po\u010dtech \u00famrt\u00ed na zhoubn\u00e1 n\u00e1dorov\u00e1 onemocn\u011bn\u00ed t\u0159et\u00ed m\u00edsto, hned po karcinomu plic a rakovin\u011b tlust\u00e9ho st\u0159eva. Leuk\u00e9mii, lymfomu \u010di mnoho\u010detn\u00e9mu myelomu podlehli zp\u011bv\u00e1k Karel Gott, man\u017eelka zavra\u017ed\u011bn\u00e9ho americk\u00e9ho prezidenta Kennedyho Jacqueline nebo cyklista Lubo\u0161 Lom, \u00fa\u010dastn\u00edk olympijsk\u00fdch her v Soulu.<\/p>\n\n\n\n
Do hry na\u0161t\u011bst\u00ed st\u00e1le v\u00edce vstupuje imunoterapie, kter\u00e1 \u0159ad\u011b pacient\u016f v\u00fdznamn\u011b prodlu\u017euje \u017eivot.<\/p>\n\n\n\n
Krevn\u00ed zhoubn\u00e9 n\u00e1dory p\u0159edstavuj\u00ed \u0161irok\u00e9 spektrum n\u00e1dorov\u00fdch onemocn\u011bn\u00ed, kter\u00e1 postihuj\u00ed kostn\u00ed d\u0159e\u0148 a lymfatick\u00e9 uzliny. V posledn\u00edch desetilet\u00edch medic\u00edna hodn\u011b pokro\u010dila v jejich diagnostice a l\u00e9\u010db\u011b, p\u0159esto \u0159ada z nich z\u016fst\u00e1v\u00e1 nevyl\u00e9\u010diteln\u00fdch a ka\u017edoro\u010dn\u011b jsou v \u010cesk\u00e9 republice p\u0159\u00ed\u010dinou smrti 2000 pacient\u016f.<\/p>\n\n\n\n
Nej\u010dast\u011bj\u0161\u00edm z typ\u016f rakoviny krve je leuk\u00e9mie, p\u0159i n\u00ed\u017e doch\u00e1z\u00ed k poru\u0161e tvorby b\u00edl\u00fdch krvinek v kostn\u00ed d\u0159eni. K dal\u0161\u00edm pat\u0159\u00ed mnoho\u010detn\u00fd myelom, nebo nap\u0159\u00edklad lymfom \u2013 n\u00e1dorov\u00e9 onemocn\u011bn\u00ed lymfatick\u00e9ho syst\u00e9mu, jeho\u017e bu\u0148ky se nekontrolovan\u011b mno\u017e\u00ed, posti\u017een\u00e1 uzlina se za\u010dne zv\u011bt\u0161ovat a ztr\u00e1c\u00ed svou p\u016fvodn\u00ed funkci.<\/p>\n\n\n\n
Mnoho\u010detn\u00fd myelom je druh\u00fd<\/p>\n\n\n\n
Na druh\u00e9m m\u00edst\u011b v po\u010dtu p\u0159\u00edpad\u016f je mnoho\u010detn\u00fd myelom, zhoubn\u00e1 choroba, kter\u00e1 vznik\u00e1 nekontrolovan\u00fdm mno\u017een\u00edm myelomov\u00fdch bun\u011bk v kostn\u00ed d\u0159eni. Jedn\u00e1 se p\u0159edev\u0161\u00edm o onemocn\u011bn\u00ed senior\u016f: nejvy\u0161\u0161\u00ed v\u00fdskyt je ve v\u011bkov\u00e9 skupin\u011b 65 a\u017e 74 let.<\/p>\n\n\n\n
V \u010cesk\u00e9 republice je ro\u010dn\u011b diagnostikov\u00e1no p\u0159ibli\u017en\u011b 500 osob s mnoho\u010detn\u00fdm myelomem a v sou\u010dasn\u00e9 dob\u011b se s t\u00edmto onemocn\u011bn\u00edm l\u00e9\u010d\u00ed zhruba 4000 pacient\u016f. Pr\u00e1v\u011b tato diagn\u00f3za m\u00e1 30. b\u0159ezna sv\u00e9 m\u00edsto v kalend\u00e1\u0159i. N\u00e1rodn\u00ed den myelomu m\u00e1 c\u00edl zv\u00fd\u0161it pov\u011bdom\u00ed ve\u0159ejnosti o t\u00e9to nemoci a o mo\u017enostech l\u00e9\u010dby.<\/p>\n\n\n\n
Velkou nad\u011bj\u00ed pro nemocn\u00e9 s mnoho\u010detn\u00fdm myelomem se v posledn\u00edch letech stala zejm\u00e9na c\u00edlen\u00e1 biologick\u00e1 l\u00e9\u010dba. V \u010cesk\u00e9 republice je registrov\u00e1na od roku 2016 a d\u00edky n\u00ed se p\u0159e\u017eit\u00ed pacient\u016f zdvojn\u00e1sobilo.<\/p>\n\n\n\n
\u201eJedn\u00e1 se o obrovsk\u00fd pokrok \u2013 na konci minul\u00e9ho stolet\u00ed se p\u0159e\u017eit\u00ed pacient\u016f s myelomem pohybovalo kolem t\u0159\u00ed let. Dnes se p\u011bti let do\u017e\u00edv\u00e1 ka\u017ed\u00fd druh\u00fd a t\u0159etina pacient\u016f \u017eije d\u00edky l\u00e9\u010db\u011b deset let,\u201c \u0159\u00edk\u00e1 profesor Roman H\u00e1jek, p\u0159ednosta Kliniky hematoonkologie Fakultn\u00ed nemocnice Ostrava a p\u0159edseda \u010cesk\u00e9 myelomov\u00e9 skupiny.<\/p>\n\n\n\n
Skute\u010dn\u011b zlomov\u00fdm miln\u00edkem v l\u00e9\u010db\u011b se pomalu st\u00e1v\u00e1 imunoterapie, kter\u00e1 je mimo\u0159\u00e1dn\u011b \u00fa\u010dinn\u00e1 u \u0159ady v\u0161ech druh\u016f n\u00e1dor\u016f krve.<\/p>\n\n\n\n
Jedn\u00e1 se o jak\u00e9si pos\u00edlen\u00ed p\u0159irozen\u00fdch mechanism\u016f imunitn\u00edho syst\u00e9mu pacienta tak, aby byl schopen intenzivn\u011bji bojovat s nemoc\u00ed. Metoda ukazuje velmi slibn\u00e9 v\u00fdsledky nejen u myelomu, ale i v l\u00e9\u010db\u011b jin\u00fdch onkologick\u00fdch onemocn\u011bn\u00ed.<\/p>\n\n\n\n
Varovn\u00e1 \u00fanava a bolesti kost\u00ed<\/p>\n\n\n\n
S diagn\u00f3zou mnoho\u010detn\u00e9ho myelomu \u017eije i 63let\u00e1 pan\u00ed Olga. Zhruba p\u0159ed \u0161esti lety se jej\u00ed zdravotn\u00ed stav za\u010dal zhor\u0161ovat. Prod\u011blala opakovan\u011b z\u00e1n\u011bty pr\u016fdu\u0161ek, z\u00e1pal plic, trp\u011bla vy\u010derp\u00e1n\u00edm a bolestmi p\u00e1te\u0159e. Na za\u010d\u00e1tku roku 2017 ode\u0161la do p\u0159ed\u010dasn\u00e9ho d\u016fchodu v nad\u011bji, \u017ee bude v\u00edce odpo\u010d\u00edvat a jej\u00ed zdravotn\u00ed stav se zlep\u0161\u00ed.<\/p>\n\n\n\n
Ob\u010das si dop\u0159\u00e1vala l\u00e1ze\u0148sk\u00e9 pobyty a dovolen\u00e9 u mo\u0159e, sna\u017eila se cvi\u010dit, plavat a tr\u00e1vit \u010das s rodinou. Ale i p\u0159es ob\u010dasnou \u00falevu se jej\u00ed zdravotn\u00ed stav nad\u00e1le zhor\u0161oval. P\u0159ib\u00fdvaly zejm\u00e9na bolesti kost\u00ed a celkov\u00e1 slabost, nev\u00fdkonnost.<\/p>\n\n\n\n
P\u0159\u00edznaky st\u00e1\u0159\u00ed, nebo rakovina?<\/p>\n\n\n\n
V \u00fanoru 2020 p\u0159ekonala ch\u0159ipku a od t\u00e9 doby nabraly v\u011bci rychl\u00fd sp\u00e1d. Bolesti sval\u016f, p\u00e1te\u0159e a kost\u00ed se staly nesnesiteln\u00fdmi a du\u0161nost j\u00ed nedovolila vyj\u00edt by\u0165 jen p\u00e1r schod\u016f. Tr\u00e1pila ji v\u00fdrazn\u00e1 \u00fanava a vy\u010derp\u00e1n\u00ed, \u017eivotn\u00ed s\u00edla se vytr\u00e1cela.<\/p>\n\n\n\n
Pot\u00ed\u017ee vyvrcholily v \u010dervenci 2020, kdy ji obvodn\u00ed l\u00e9ka\u0159ka na z\u00e1klad\u011b v\u00fdsledk\u016f vy\u0161et\u0159en\u00ed krve a mo\u010di poslala na transfuzi do okresn\u00ed nemocnice. Odtud u\u017e n\u00e1sledoval p\u0159evoz na hematoonkologickou kliniku, kde Olga podstoupila odb\u011br kostn\u00ed d\u0159en\u011b. Ten bohu\u017eel potvrdil n\u00e1dorov\u00e9 onemocn\u011bn\u00ed a nep\u0159\u00edznivou diagn\u00f3zu \u2013 mnoho\u010detn\u00fd myelom.<\/p>\n\n\n\n
Dv\u011b studie a mezi nimi covid<\/p>\n\n\n\n
Olga se hned dostala do klinick\u00e9 studie, p\u0159i n\u00ed\u017e u\u017e\u00edvala novou kombinaci l\u00e9k\u016f a hladina \u0161kodliv\u00fdch l\u00e1tek produkovan\u00fdch n\u00e1dorov\u00fdmi bu\u0148kami za\u010dala rychle klesat.<\/p>\n\n\n\n
V \u0159\u00edjnu 2020 ale Olga onemocn\u011bla covidem chytila covid-19, m\u011bla t\u011b\u017ek\u00fd pr\u016fb\u011bh a z klinick\u00e9 studie nakonec na vlastn\u00ed \u017e\u00e1dost vystoupila. L\u00e9ka\u0159i proto pokra\u010dovali standardn\u00ed dostupnou terapi\u00ed, ta ale po n\u011bkolika m\u011bs\u00edc\u00edch velk\u00e9 \u00falevy p\u0159estala zab\u00edrat. Na za\u010d\u00e1tku roku 2022 se Olze nemoc op\u011bt vr\u00e1tila.<\/p>\n\n\n\n
\u201eNa\u0161t\u011bst\u00ed jsem dostala mo\u017enost vyu\u017e\u00edt imunoterapie a vstoupit do dal\u0161\u00ed studie s jinou kombinac\u00ed l\u00e9k\u016f, kterou jsem zvl\u00e1dala dob\u0159e,\u201c \u0159\u00edk\u00e1 Olga.<\/p>\n\n\n\n
V z\u00e1\u0159\u00ed p\u0159i\u0161la dobr\u00e1 zpr\u00e1va \u2013 \u0161kodliv\u00e9 l\u00e1tky produkovan\u00e9 n\u00e1dorov\u00fdmi bu\u0148kami u\u017e nebyly v krvi pan\u00ed Olgy prok\u00e1z\u00e1ny.<\/p>\n\n\n\n
K odstran\u011bn\u00ed zbytkov\u00e9 nemoci j\u00ed l\u00e9ka\u0159i doporu\u010dili takzvanou autologn\u00ed transplantaci krvetvorn\u00fdch bun\u011bk. P\u0159i n\u00ed jsou pacient\u016fm odebr\u00e1ny a n\u00e1sledn\u011b zamra\u017eeny jejich vlastn\u00ed krvetvorn\u00e9 bu\u0148ky. Pacient pak podstoup\u00ed vysokod\u00e1vkovou chemoterapii, kter\u00e1 zni\u010d\u00ed zbyl\u00e9 n\u00e1dorov\u00e9 bu\u0148ky, ale \u010dasto po\u0161kozuje i zdrav\u00e9 bu\u0148ky kostn\u00ed d\u0159en\u011b a imunitn\u00edho syst\u00e9mu.<\/p>\n\n\n\n
Po ukon\u010den\u00ed chemoterapie jsou proto tyto p\u0159edem z\u00edskan\u00e9 kmenov\u00e9 bu\u0148ky transplantov\u00e1ny zp\u011bt do t\u011bla pacienta. To umo\u017e\u0148uje obnovu kostn\u00ed d\u0159en\u011b a imunitn\u00edho syst\u00e9mu, co\u017e pom\u00e1h\u00e1 pacientovi rychleji se zotavit. Olga m\u00e1 tuto l\u00e9\u010dbu podstoupit letos na ja\u0159e. \u201eJsem r\u00e1da, \u017ee jsem m\u011bla to \u0161t\u011bst\u00ed, a mohla jsem b\u00fdt za\u0159azena do studi\u00ed, kter\u00e9 mi d\u00edky nejnov\u011bj\u0161\u00edm l\u00e9\u010debn\u00fdm metod\u00e1m pomohly mnoho\u010detn\u00fd myelom zvl\u00e1dnout a vr\u00e1tily m\u011b do \u017eivota,\u201c dod\u00e1v\u00e1 Olga.<\/p>\n\n\n\n
Kter\u00e9 celebrity postihla rakovina krve:<\/p>\n\n\n\n
Karel Gott<\/p>\n\n\n\n
V \u0159\u00edjnu 2015 mu byl diagnostikov\u00e1n Non-Hodgkin\u016fv lymfom, se kter\u00fdm se l\u00e9\u010dil ve V\u0161eobecn\u00e9 fakultn\u00ed nemocnici Praha. V roce 2018 se u n\u011bj objevila porucha krvetvorby a v polovin\u011b z\u00e1\u0159\u00ed n\u00e1sleduj\u00edc\u00edho roku probl\u00e9my p\u0159erostly v akutn\u00ed leuk\u00e9mii, na jej\u00ed\u017e n\u00e1sledky zem\u0159el.<\/p>\n\n\n\n
Andrej Hryc<\/p>\n\n\n\n
Slovensk\u00fd herec, kter\u00fd hr\u00e1l v Ulicii nebo t\u0159eba ve filmu B\u00e1thory. V dubnu 2020 mu byla diagnostikov\u00e1na akutn\u00ed leukemie, kter\u00e9 podlehl 31. ledna 2021.<\/p>\n\n\n\n
Jeff Bridges<\/p>\n\n\n\n
Oscarov\u00fd herec a hv\u011bzda filmu Big Lebowski m\u00e1 zhoubn\u00fd lymfom.<\/p>\n\n\n\n
Jacqueline Kennedy Onassis<\/p>\n\n\n\n
B\u00fdval\u00e1 prvn\u00ed d\u00e1ma USA m\u011bla Non-Hodgkin\u016fv lymfom. 19. kv\u011btna 1994 se j\u00ed z\u00e1ke\u0159n\u00e1 nemoc stala osudnou a lymfomu podlehla.<\/p>\n\n\n\n
Jane Fonda<\/p>\n\n\n\n
Americk\u00e1 here\u010dka loni v z\u00e1\u0159\u00ed na soci\u00e1ln\u00edch s\u00edt\u00edch ozn\u00e1mila, \u017ee m\u00e1 zhoubn\u00fd Non-Hodgkin\u016fv lymfom. P\u0159ed sv\u00fdmi 85. narozeninami loni v prosinci pak uvedla, \u017ee j\u00ed l\u00e9ka\u0159i dali kr\u00e1sn\u00fd d\u00e1rek a je pr\u00fd z nemoci uzdravena.<\/p>\n\n\n\n
Lubo\u0161 Lom<\/p>\n\n\n\n
Cyklista, \u00fa\u010dastn\u00edk olympijsk\u00fdch her v Soulu onemocn\u011bl v roce 2013 mnoho\u010detn\u00fdm myelomem. D\u00edky sv\u00e9 vytrvalosti, velk\u00e9 podpo\u0159e rodiny i sv\u00fdch fanou\u0161k\u016f nemoci vzdoroval dlouh\u00fdch dev\u011bt let. Zem\u0159el v \u00fanoru 2022 v 57 letech.<\/p>\n\n\n\n
Tom Brokaw<\/p>\n\n\n\n
Zn\u00e1m\u00fd americk\u00fd novin\u00e1\u0159 a televizn\u00ed moder\u00e1tor oslavil ji\u017e 83. narozeniny, m\u00e1 myelom od roku 2013.<\/p>\n\n\n\n
David Maria Sassoli<\/p>\n\n\n\n
Italsk\u00fd politik a novin\u00e1\u0159, p\u0159edseda Evropsk\u00e9ho parlamentu, zem\u0159el b\u011bhem sv\u00e9 funkce na mnoho\u010detn\u00fd myelom loni v lednu.<\/p>\n\n\n\n
M\u00e1m to v krvi<\/p>\n\n\n\n
– V r\u00e1mci N\u00e1rodn\u00edho dne myelomu se rozb\u00edh\u00e1 osv\u011btov\u00e1 kampa\u0148 s n\u00e1zvem \u201eM\u00e1m to v krvi\u201c. Krom\u011b jin\u00e9ho upozor\u0148uje na nov\u00e9, nad\u011bjn\u00e9 mo\u017enosti l\u00e9\u010dby tohoto onemocn\u011bn\u00ed, jako je imunoterapie, respektive terapie geneticky modifikovan\u00fdmi b\u00edl\u00fdmi krvinkami, kter\u00e9 by v bl\u00edzk\u00e9 budoucnosti mohly znamenat z\u00e1sadn\u00ed pr\u016flom v l\u00e9\u010db\u011b. V\u00edce na www.mamtovkrvi.cz<\/p>\n\n\n\n
– Objektivn\u00ed informace o mnoho\u010detn\u00e9m myelomu lze z\u00edskat z web\u016f www.myeloma.cz nebo www.mnohocetnymyelom.cz, p\u0159\u00edpadn\u011b na webov\u00fdch str\u00e1nk\u00e1ch spole\u010dnosti Janssen.<\/p>\n\n\n\n
Zdena Lackov\u00e1<\/p>\n\n\n\n
Den\u00edk.cz<\/p>\n\n\n\n
https:\/\/www.denik.cz\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":" Rakovina krve zauj\u00edm\u00e1 v po\u010dtech \u00famrt\u00ed na zhoubn\u00e1 n\u00e1dorov\u00e1 onemocn\u011bn\u00ed t\u0159et\u00ed m\u00edsto, hned po karcinomu plic a rakovin\u011b tlust\u00e9ho st\u0159eva. Leuk\u00e9mii, lymfomu \u010di mnoho\u010detn\u00e9mu myelomu […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":27915,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-38878","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/38878","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=38878"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/38878\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/27915"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=38878"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=38878"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=38878"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}