{"id":42147,"date":"2023-09-14T07:36:57","date_gmt":"2023-09-14T05:36:57","guid":{"rendered":"https:\/\/www.invarena.cz\/?p=42147"},"modified":"2023-09-14T07:36:58","modified_gmt":"2023-09-14T05:36:58","slug":"moderni-leky-v-cesku-nechybi-leci-se-jimi-ale-jen-mizive-procento-pacientu","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=42147","title":{"rendered":"MODERN\u00cd L\u00c9KY V \u010cESKU NECHYB\u00cd, L\u00c9\u010c\u00cd SE JIMI ALE JEN MIZIV\u00c9 PROCENTO PACIENT\u016e"},"content":{"rendered":"\n

Prvn\u00edch p\u011bt let po ustaven\u00ed Sv\u011btov\u00e9ho dne atopick\u00e9 dermatitidy, kter\u00fd p\u0159ipad\u00e1 na 14. z\u00e1\u0159\u00ed, p\u0159ineslo \u0159adu p\u0159evratn\u00fdch zm\u011bn. Na \u010desk\u00fd trh vstoupilo hned n\u011bkolik inovativn\u00edch p\u0159\u00edpravk\u016f, v\u010detn\u011b l\u00e9k\u016f ve form\u011b tobolek, kter\u00e9 si um\u00ed poradit i s\u00a0t\u011bmi nejz\u00e1va\u017en\u011bj\u0161\u00edmi stupni onemocn\u011bn\u00ed. V\u00a0\u010cesk\u00e9 republice vznikla za \u00fa\u010delem zp\u0159\u00edstupn\u011bn\u00ed modern\u00ed terapie s\u00ed\u0165 v\u00edce ne\u017e \u010dty\u0159iceti specializovan\u00fdch center i zvl\u00e1\u0161tn\u00ed registr pro zaznamen\u00e1v\u00e1n\u00ed \u00fadaj\u016f o l\u00e9\u010db\u011b. I p\u0159es tyto pokroky ale z\u016fst\u00e1v\u00e1 po\u010det osob l\u00e9\u010den\u00fdch nejmodern\u011bj\u0161\u00edmi metodami velmi n\u00edzk\u00fd: tyto l\u00e9ky u\u017e\u00edvaj\u00ed pouze p\u0159ibli\u017en\u011b 4 % v\u0161ech pacient\u016f, kte\u0159\u00ed na ni maj\u00ed n\u00e1rok. Nemoc jim tak nad\u00e1le v\u00fdznamn\u011b komplikuje \u017eivot.<\/strong><\/p>\n\n\n\n

Atopick\u00e1 dermatitida neboli atopick\u00fd ekz\u00e9m je z\u00e1n\u011btliv\u00e9 onemocn\u011bn\u00ed k\u016f\u017ee, kter\u00e9 si laick\u00e1 ve\u0159ejnost \u010dasto spojuje s lehkou vyr\u00e1\u017ekou v d\u011btsk\u00e9m v\u011bku. \u201eJen v \u010cesk\u00e9 republice ale \u017eije p\u0159ibli\u017en\u011b 21 700 osob se z\u00e1va\u017en\u00fdmi formami onemocn\u011bn\u00ed, kter\u00fdm sv\u011bd\u011bn\u00ed, bolest a nutnost slo\u017eit\u011b pe\u010dovat o poko\u017eku v\u00fdrazn\u011b naru\u0161uj\u00ed osobn\u00ed i pracovn\u00ed \u017eivot. Nemoc vede k poruch\u00e1m sp\u00e1nku, \u010dast\u00fdm ko\u017en\u00edm infekc\u00edm i \u00fanav\u011b a depres\u00edm, 79 % pacient\u016f nav\u00edc trp\u00ed alergiemi na pyl, rozto\u010de, zv\u00ed\u0159ec\u00ed srst nebo potraviny,\u201c uv\u00e1d\u00ed na pravou m\u00edru za\u017eitou p\u0159edstavu o atopick\u00e9 dermatitid\u011b prof. MUDr. Monika Arenbergerov\u00e1, Ph.D., z Fakultn\u00ed nemocnice Kr\u00e1lovsk\u00e9 vinohrady v Praze<\/strong>. <\/p>\n\n\n\n

Nezanedbateln\u00e9 jsou tak\u00e9 finan\u010dn\u00ed dopady onemocn\u011bn\u00ed. \u201eZ praxe zn\u00e1me pacienty, kte\u0159\u00ed v zoufal\u00e9 snaze naj\u00edt prost\u0159edek, kter\u00fd jim ulev\u00ed od neust\u00e1l\u00fdch obt\u00ed\u017e\u00ed, utrat\u00ed za dermokosmetiku i \u010dty\u0159i nebo p\u011bt tis\u00edc korun m\u011bs\u00ed\u010dn\u011b. Samotn\u00e1 p\u00e9\u010de o poko\u017eku, opakovan\u00e9 sprchov\u00e1n\u00ed a promaz\u00e1v\u00e1n\u00ed k\u016f\u017ee mohou zabrat i dv\u011b hodiny denn\u011b. Dermatitida tak p\u0159edstavuje obrovsk\u00fd z\u00e1sah do \u017eivota pacient\u016f i rodiny doslova po v\u0161ech str\u00e1nk\u00e1ch,\u201c podot\u00fdk\u00e1 Ing. Josef Poh\u016fnek, prezident pacientsk\u00e9 organizace SPAE<\/strong>, kter\u00e1 sdru\u017euje pacienty s atopickou dermatitidou a psori\u00e1zou.<\/p>\n\n\n\n

Inovace v l\u00e9\u010db\u011b<\/strong><\/p>\n\n\n\n

P\u0159ed rokem 2019 byli \u010de\u0161t\u00ed pacienti se z\u00e1va\u017en\u00fdmi formami atopick\u00e9 dermatitidy odk\u00e1zan\u00ed pouze na topickou l\u00e9\u010dbu v podob\u011b mast\u00ed nebo na imunosupresiva, tedy l\u00e9ky na potla\u010den\u00ed imunitn\u00ed reakce, kter\u00e1 s sebou \u010dasto nesou \u0159adu ne\u017e\u00e1douc\u00edch \u00fa\u010dink\u016f. S p\u0159\u00edchodem biologick\u00e9 l\u00e9\u010dby, kterou prov\u00e1zel rozvoj specializovan\u00fdch center, se pacient\u016fm naskytla mo\u017enost \u0161etrn\u011bj\u0161\u00ed a \u00fa\u010dinn\u011bj\u0161\u00ed terapie.<\/p>\n\n\n\n

Nev\u00fdhodou biologik v\u0161ak m\u016f\u017ee b\u00fdt aplikace ve form\u011b injekc\u00ed, na kter\u00e9 pacienti pravideln\u011b doj\u00ed\u017ed\u00ed nebo si l\u00e9\u010dbu pod\u00e1vaj\u00ed sami. Injek\u010dn\u00ed u\u017eit\u00ed l\u00e9ku je ale pro \u0159adu pacient\u016f nep\u0159\u00edjemn\u00e9 natolik, \u017ee je od l\u00e9\u010dby m\u016f\u017ee odradit. V\u00fdznamnou roli m\u016f\u017ee hr\u00e1t i strach z jehel, kter\u00fd podle pr\u016fzkum\u016f poci\u0165uje okolo 10 % procent populace. Z ned\u00e1vn\u00fdch pr\u016fzkum\u016f v n\u011bkolika evropsk\u00fdch zem\u00edch vyplynulo, \u017ee nemocn\u00ed jednozna\u010dn\u011b d\u00e1vaj\u00ed mo\u017enost jin\u00e9mu zp\u016fsobu pod\u00e1n\u00ed. Tuto volbu maj\u00ed nov\u011b tak\u00e9 pacienti v \u010cesk\u00e9 republice. \u201eNejnov\u011bj\u0161\u00ed typ l\u00e9k\u016f, takzvan\u00e1 c\u00edlen\u00e1 l\u00e9\u010dba pomoc\u00ed mal\u00fdch molekul, je dostupn\u00fd ve form\u011b tobolek. Odpad\u00e1 tak nutnost \u010dast\u00fdch n\u00e1v\u0161t\u011bv centra nebo psychick\u00e1 bari\u00e9ra spojen\u00e1 s nutnost\u00ed aplikovat si injekci s\u00e1m,\u201c \u0159\u00edk\u00e1 MUDr. Arenbergerov\u00e1<\/strong>.<\/p>\n\n\n\n

L\u00e9\u010d\u00ed se jen ka\u017ed\u00fd p\u011btadvac\u00e1t\u00fd<\/strong><\/p>\n\n\n\n

Modern\u00ed l\u00e9\u010dbu mohou pacient\u016fm se z\u00e1va\u017enou atopickou dermatitidou p\u0159edepisovat pouze specialist\u00e9 z Center biologick\u00e9 a c\u00edlen\u00e9 l\u00e9\u010dby. V \u010cesk\u00e9 republice jich funguje p\u0159es 40 a nach\u00e1zej\u00ed se v ka\u017ed\u00e9m kraji. L\u00e9\u010dba je tak dob\u0159e dostupn\u00e1, p\u0159esto ji vyu\u017e\u00edv\u00e1 jen nepatrn\u00fd zlomek z t\u011bch, kdo na ni maj\u00ed n\u00e1rok.<\/p>\n\n\n\n

Data z posledn\u00ed zpr\u00e1vy registru BIOREP, kter\u00fd mimo jin\u00e9 eviduje \u00fadaje o pacientech s atopick\u00fdm ekz\u00e9mem na modern\u00ed l\u00e9\u010db\u011b, mluv\u00ed jasn\u011b. \u201eV roce 2022 se nejmodern\u011bj\u0161\u00edmi typy l\u00e9k\u016f l\u00e9\u010dilo jen 808 pacient\u016f, z toho 432 mu\u017e\u016f a 376 \u017een. To jsou zhruba 4 % z t\u011bch, kdo by z l\u00e9\u010dby mohli profitovat \u2013 tedy osob s t\u011b\u017ek\u00fdm stupn\u011bm atopick\u00e9ho ekz\u00e9mu, s nedostate\u010dnou odezvou na terapii mastmi nebo imunosupresivy,\u201c p\u0159ibli\u017euje Josef Poh\u016fnek ze SPAE<\/strong>. \u201eJe pravda, \u017ee oproti roku 2021 do\u0161lo ke 100% n\u00e1r\u016fstu po\u010dtu takto l\u00e9\u010den\u00fdch pacient\u016f. Po\u0159\u00e1d jsme ale v situaci, kdy 24 z 25 pacient\u016f nem\u00e1 \u00fa\u010dinnou l\u00e9\u010dbu. L\u00e9\u010dbu podstupuj\u00ed nav\u00edc t\u00e9m\u011b\u0159 v\u00fdhradn\u011b pacienti s t\u011b\u017ek\u00fdm stupn\u011bm nemoci, p\u0159esto\u017ee n\u00e1rok na ni by m\u011bli m\u00edt i lid\u00e9 se st\u0159edn\u011b t\u011b\u017ekou formou,\u201c zam\u00fd\u0161l\u00ed se.<\/p>\n\n\n\n

Ke zv\u00fd\u0161en\u00ed po\u010dtu spr\u00e1vn\u011b l\u00e9\u010den\u00fdch pacient\u016f se z\u00e1va\u017en\u00fdmi formami atopick\u00e9 dermatitidy by mohla p\u0159isp\u011bt tak\u00e9 osv\u011btov\u00e1 kampa\u0148, kterou nyn\u00ed SPAE po\u0159\u00e1d\u00e1. \u201eChceme uk\u00e1zat, \u017ee \u00fa\u010dinn\u00e1 l\u00e9\u010dba existuje a je dostupn\u00e1 i pacient\u016fm v\u00a0\u010cesk\u00e9 republice. A tak\u00e9 p\u0159isp\u011bt k\u00a0bo\u0159en\u00ed m\u00fdtu, \u017ee atopick\u00fd ekz\u00e9m je jen lehk\u00e1 vyr\u00e1\u017eka,\u201c uzav\u00edr\u00e1 Josef Poh\u016fnek<\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Prvn\u00edch p\u011bt let po ustaven\u00ed Sv\u011btov\u00e9ho dne atopick\u00e9 dermatitidy, kter\u00fd p\u0159ipad\u00e1 na 14. z\u00e1\u0159\u00ed, p\u0159ineslo \u0159adu p\u0159evratn\u00fdch zm\u011bn. Na \u010desk\u00fd trh vstoupilo hned n\u011bkolik inovativn\u00edch […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":42149,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-42147","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/42147","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=42147"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/42147\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/42149"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=42147"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=42147"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=42147"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}