{"id":55827,"date":"2025-03-21T10:32:23","date_gmt":"2025-03-21T09:32:23","guid":{"rendered":"https:\/\/www.invarena.cz\/?p=55827"},"modified":"2025-03-21T10:32:28","modified_gmt":"2025-03-21T09:32:28","slug":"hleda-se-pro-ni-darce-kostni-drene","status":"publish","type":"post","link":"https:\/\/www.invarena.cz\/?p=55827","title":{"rendered":"Hled\u00e1 se pro ni d\u00e1rce kostn\u00ed d\u0159en\u011b\u00a0\u00a0"},"content":{"rendered":"\n

\u010cT 1\u00a0– Ud\u00e1losti

A te\u010f p\u0159\u00edb\u011bh Madlen, d\u00edvky s v\u00e1\u017enou poruchou krvetvorby. Jej\u00ed nejbli\u017e\u0161\u00ed hledaj\u00ed, kdo by poskytl kostn\u00ed d\u0159e\u0148. Z p\u0159\u00edbuzn\u00fdch se nehod\u00ed nikdo.

Otec Madelene ve\u0159ejn\u011b vyz\u00fdv\u00e1, aby se lid\u00e9 zapsali do jednoho z registr\u016f. Reaguj\u00ed stovky dobrovoln\u00edk\u016f. Rodina d\u00edvky nen\u00ed jedin\u00e1, kter\u00e1 sh\u00e1n\u00ed pomoc. Vhodn\u00e9ho d\u00e1rce zat\u00edm nem\u00e1 v\u00edc ne\u017e 100 pacient\u016f. Lid\u00e9 tak mohou pomoci nejen v tomto konkr\u00e9tn\u00edm p\u0159\u00edpad\u011b.

20 m\u011bs\u00edc\u016f byla \u00fapln\u011b zdrav\u00e9 d\u00edt\u011b. Jen jednou onemocn\u011bla s vysok\u00fdmi hore\u010dkami. Na za\u010d\u00e1tku b\u0159ezna jeli do\u00a0nemocnice<\/strong>\u00a0s vyr\u00e1\u017ekou.

Luk\u00e1\u0161 P\u0159ibyl, otec Madlen
——————–
J\u00e1 se p\u0159izn\u00e1m, \u017ee jsem tomu nep\u0159ikl\u00e1dal \u017e\u00e1dnou extra v\u00e1hu. o\u010dek\u00e1val jsem, \u017ee to je typicky z raj\u010dat, proto\u017ee raj\u010data miluje. Nicm\u00e9n\u011b se uk\u00e1zalo, \u017ee se vlastn\u011b nejedn\u00e1 o vyr\u00e1\u017eku, ale \u017ee se jedn\u00e1 o tzv. petechie.

redaktorka \u010cT
——————–
V\u00a0nemocnici<\/strong>\u00a0si ji u\u017e nechali. Nikoho jin\u00e9ho krom\u011b rodiny k n\u00ed nepou\u0161t\u00ed. Otec za n\u00ed m\u016f\u017ee jen v rou\u0161ce. Mal\u00e9 Madlen u\u017e nefunguje imunitn\u00ed syst\u00e9m.

Luk\u00e1\u0161 P\u0159ibyl, otec Madlen
——————–
Ono to na n\u00ed pomalu ani nepozn\u00e1te, \u010d\u00edm\u017e je to mo\u017en\u00e1 je\u0161t\u011b z\u00e1udn\u011bj\u0161\u00ed vlastn\u011b cel\u00fd. Takhle jsem s n\u00edm byl vlastn\u011b na odd\u011blen\u00ed, kdy si hraje s panenkou a a\u017e nepochopiteln\u00fd, proto\u017ee ona m\u00e1 v tuhletu chv\u00edli hodnoty takov\u00fd, \u017ee v\u011bt\u0161ina lid\u00ed u\u017e d\u00e1vno spala. Byla by takov\u00e1 jako hibernovan\u00e1.

Renata Form\u00e1nkov\u00e1, vedouc\u00ed Transplanta\u010dn\u00ed jednotky, FN Motol
——————–
Madlenka m\u00e1 onemocn\u011bn\u00ed, kter\u00e9 se naz\u00fdv\u00e1 t\u011b\u017ek\u00e1 aplastick\u00e1 an\u00e9mie. Znamen\u00e1 to, \u017ee vlastn\u011b v kostn\u00ed d\u0159eni se p\u0159estanou tvo\u0159it b\u00edl\u00e9 krvinky, \u010derven\u00e9 krvinky i krevn\u00ed desti\u010dky. A bez adekv\u00e1tn\u00ed l\u00e9\u010dby, d\u00e1 se \u0159\u00edct, dlouhodob\u011b neslu\u010diteln\u00e9 se \u017eivotem.

redaktorka \u010cT
——————–
Zachr\u00e1nit by ji mohl vhodn\u00fd d\u00e1rce kostn\u00ed d\u0159en\u011b. Nejv\u011bt\u0161\u00ed \u0161ance na \u00fasp\u011bch je u sourozenc\u016f. Madlen m\u00e1 t\u0159i, ani jeden se jako d\u00e1rce pro sestru nehod\u00ed.

Luk\u00e1\u0161 P\u0159ibyl, otec Madlen
——————–
To jako regul\u00e9rn\u00ed bezmoc. J\u00e1 se sna\u017e\u00edm bejt t\u00e1ta, kterej celou tu rodinu ochr\u00e1n\u00ed a oto\u010dil by zem\u011bkouli, aby se ot\u00e1\u010del na druhou stranu, ale j\u00e1 nejsem schopn\u00fd ud\u011blat v\u00edc.

redaktorka \u010cT
——————–
Rozhodl se alespo\u0148 zve\u0159ejnit p\u0159\u00edb\u011bh svoj\u00ed dcery na soci\u00e1ln\u00edch s\u00edt\u00edch s v\u00fdzvou, aby se lid\u00e9 \u0161li zapsat do registru d\u00e1rc\u016f a reakce p\u0159i\u0161la okam\u017eit\u011b.

sestra v transfuzn\u00ed stanici
——————–
My m\u00e1me podm\u00ednku pro vstup 18\u201340 let. Spl\u0148ujete?

Marie Ku\u0159\u00edkov\u00e1, \u010cesk\u00fd registr d\u00e1rc\u016f krvetvorn\u00fdch bun\u011bk, IKEM
——————–
To jsou stovky p\u0159ihl\u00e1\u0161ek denn\u011b, b\u011b\u017en\u011b m\u00e1me p\u00e1r t\u011bch p\u0159ihl\u00e1\u0161ek.

sestra v transfuzn\u00ed stanici
——————–
Nechte zatnutou ruku.

redaktorka \u010cT
——————–
Na v\u00fdzvu p\u0159i\u0161la i Monika Koz\u00e1kov\u00e1.

Monika Koz\u00e1kov\u00e1, nov\u011b registrovan\u00e1 d\u00e1rkyn\u011b
——————–
J\u00e1 jsem o tom uva\u017eovala u\u017e del\u0161\u00ed dobu, ale ten hlavn\u00ed impuls bylo video tat\u00ednka mal\u00e9 hol\u010di\u010dky na Instagramu. Hlavn\u011b proto, \u017ee m\u00e1m d\u011bti sama.

redaktorka \u010cT
——————–
Sestra j\u00ed b\u011bhem p\u00e1r chvil odeb\u00edr\u00e1 malou ampulku krve. Pro \u00fa\u010dely registrace je to te\u010f v\u0161e. Pokud by byla pro n\u011bkoho vhodn\u00fdm d\u00e1rcem, d\u011bl\u00e1 se odb\u011br u\u017e z 90 % taky ambulantn\u011b.

Marie Ku\u0159\u00edkov\u00e1, \u010cesk\u00fd registr d\u00e1rc\u016f krvetvorn\u00fdch bun\u011bk, IKEM
——————–
Prob\u00edh\u00e1 na transfuzn\u00ed stanici. Podobn\u011b jako t\u0159eba kdy\u017e lidi chod\u00ed na plazmu nebo na desti\u010dky.

redaktorka \u010cT
——————–
Kv\u016fli samotn\u00e9mu z\u00e1pisu do registru z\u00e1jemci do\u00a0nemocnice<\/strong>\u00a0ani nemus\u00ed. D\u016fle\u017eit\u00e9 hodnoty se daj\u00ed z\u00edskat i ze st\u011bru z \u00fast. V\u0161e pot\u0159ebn\u00e9 za\u0161lou pracovn\u00edci registru dom\u016f. Pro dal\u0161\u00ed z\u00e1jemce chyst\u00e1 IKEM z\u00edtra a v sobotu hromadn\u00fd n\u00e1bor.


V \u010cesku existuj\u00ed dva registry, do kter\u00fdch se m\u016f\u017eou z\u00e1jemci zapsat. Aktu\u00e1ln\u011b v nich figuruje p\u0159es 170 000 lid\u00ed. Oba funguj\u00ed p\u0159es 30 let a za tu dobu na\u0161li p\u0159es 1300 vhodn\u00fdch d\u00e1rc\u016f. Jejich hled\u00e1n\u00ed je v p\u0159\u00edpad\u011b kostn\u00ed d\u0159en\u011b slo\u017eit\u011bj\u0161\u00ed ne\u017e u ostatn\u00edch org\u00e1n\u016f. Kdy\u017e toti\u017e l\u00e9ka\u0159i odeberou mrtv\u00fdm d\u00e1rc\u016fm t\u0159eba srdce, tla\u010d\u00ed je \u010das, proto p\u0159ed p\u0159enosem ov\u011b\u0159uj\u00ed vedle krevn\u00ed skupiny jen to, \u017ee organismus p\u0159\u00edjemce nem\u00e1 protil\u00e1tky v\u016f\u010di znak\u016fm, kter\u00e9 m\u00e1 org\u00e1n na povrchu, to, aby co nejv\u00edce sn\u00ed\u017eili riziko odm\u00edtnut\u00ed. U transplantace kostn\u00ed d\u0159en\u011b maj\u00ed l\u00e9ka\u0159i v\u00edc \u010dasu, proto hledaj\u00ed maxim\u00e1ln\u00ed shodu. Tady krevn\u00ed skupina hraje podru\u017enou roli, kl\u00ed\u010dov\u00e1 je shoda genetick\u00e1, ka\u017ed\u00fd \u010dlov\u011bk z\u00edsk\u00e1 od matky a otce po p\u011bti konkr\u00e9tn\u00edch znac\u00edch, kter\u00e9 rozhoduj\u00ed o tom, jestli transplantace bude \u00fasp\u011b\u0161n\u00e1, a a l\u00e9ka\u0159i tak hledaj\u00ed ide\u00e1ln\u011b shodu u v\u0161ech znak\u016f. Tedy 10 z 10. Nejvy\u0161\u0161\u00ed \u0161ance je u jednovaje\u010dn\u00fdch dvoj\u010dat, u b\u011b\u017en\u00fdch sourozenc\u016f u\u017e je to jen 25 % a u dal\u0161\u00edch p\u0159\u00edbuzn\u00fdch je\u0161t\u011b m\u00e9n\u011b, kdy\u017e tyto mo\u017enosti nevedou k c\u00edli, hledaj\u00ed se nep\u0159\u00edbuzn\u00ed d\u00e1rci pr\u00e1v\u011b ve specializovan\u00fdch registrech.I proto se l\u00e9ka\u0159i sna\u017e\u00ed \u0161ance pacient\u016f s leuk\u00e9mi\u00ed zvy\u0161ovat. Jak jen to jde? Metodu, p\u0159i kter\u00e9 vyu\u017e\u00edvaj\u00ed vlastnosti pupe\u010dn\u00edkov\u00fdch bun\u011bk, testuj\u00ed v \u00dastavu hematologie a krevn\u00ed transfuze v Praze, tyto bu\u0148ky toti\u017e po pod\u00e1n\u00ed pacient\u016fm um\u00ed zm\u00edrnit n\u011bkter\u00e9 komplikace po transplantaci kostn\u00ed d\u0159en\u011b.

Jaroslav Zoula, redaktor \u010cT
——————–
Jsou to lid\u00e9, u kter\u00fdch nejm\u00e9n\u011b jedna l\u00e9\u010dba leuk\u00e9mie selhala, proto jim l\u00e9ka\u0159i v dal\u0161\u00edch f\u00e1z\u00edch pod\u00e1vaj\u00ed i tzv. mezenchymov\u00e9 strom\u00e1ln\u00ed bu\u0148ky.

Robert Pytl\u00edk (vedouc\u00ed odd\u011blen\u00ed bun\u011b\u010dn\u00e9 terapie),
——————–
Jsou v mal\u00e9m mno\u017estv\u00ed p\u0159\u00edtomn\u00e9 ve v\u011bt\u0161in\u011b lidsk\u00fdch tk\u00e1n\u00ed, kde slou\u017e\u00ed k sebeobnov\u011b a tak\u00e9 k tlumen\u00ed z\u00e1n\u011btu.

Jaroslav Zoula, redaktor \u010cT
——————–
Pr\u00e1v\u011b tento efekt se po transplantac\u00edch kostn\u00ed d\u0159en\u011b vyu\u017e\u00edv\u00e1. Prvn\u00edm krokem je odebr\u00e1n\u00ed z pupe\u010dn\u00edku. Jeho mal\u00e9 kousky jsou tady pak postupn\u00e9 mno\u017een\u00ed a\u017e na stamiliony, kter\u00e9 jsou zde. L\u00e9ka\u0159i pak namno\u017een\u00e9 bu\u0148ky zmraz\u00ed a ulo\u017e\u00ed v t\u00e9to kryo bance a ty jsou tak p\u0159ipraven\u00e9 k pod\u00e1n\u00ed, podle jejich odhad\u016f ro\u010dn\u011b pom\u016f\u017eou t\u0159em a\u017e \u010dty\u0159em pacient\u016fm, i kdy\u017e tyto bu\u0148ky nejsou nikdy jedinou l\u00e9\u010dbou, jejich nasazen\u00ed se d\u00e1 br\u00e1t jako posledn\u00ed \u0161ance pro pacienty, kte\u0159\u00ed maj\u00ed jinak progn\u00f3zu dlouhodob\u00e9ho p\u0159e\u017eit\u00ed pod 15\u201320 %.

Robert Pytl\u00edk (vedouc\u00ed odd\u011blen\u00ed bun\u011b\u010dn\u00e9 terapie),
——————–
My m\u016f\u017eeme pod\u00e1n\u00edm t\u011bchto bun\u011bk zv\u00fd\u0161it jejich \u0161anci dvojn\u00e1sobn\u011b.

Jaroslav Zoula, redaktor \u010cT
——————–
V\u00fdhodou t\u011bchto bun\u011bk je tak\u00e9 fakt, \u017ee d\u00e1rkyn\u011b nemus\u00ed b\u00fdt p\u0159\u00edbuzn\u00e1 p\u0159\u00edjemce. Krom\u011b Prahy je v \u010cesku um\u00ed vyr\u00e1b\u011bt i v Plzni a v Brn\u011b. <\/p>\n\n\n\n

\u010cesk\u00e1 televize.<\/p>\n\n\n\n

<\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

\u010cT 1\u00a0– Ud\u00e1losti A te\u010f p\u0159\u00edb\u011bh Madlen, d\u00edvky s v\u00e1\u017enou poruchou krvetvorby. Jej\u00ed nejbli\u017e\u0161\u00ed hledaj\u00ed, kdo by poskytl kostn\u00ed d\u0159e\u0148. Z p\u0159\u00edbuzn\u00fdch se nehod\u00ed nikdo. […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":55846,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-55827","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/55827","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=55827"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/55827\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/55846"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=55827"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=55827"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=55827"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}