Navigovan\u00e1 chirurgie pom\u00e1h\u00e1 l\u00e9ka\u0159\u016fm p\u0159esn\u011bji operovat n\u00e1dory v t\u011ble, \u010de\u0161t\u00ed v\u011bdci te\u010f vyv\u00edjej\u00ed speci\u00e1ln\u00ed naviga\u010dn\u00ed sondy v nano velikosti, kter\u00e9 dok\u00e1\u017eou okraje n\u00e1dor\u016f doslova rozsv\u00edtit.<\/p>\n\n\n\n
Chirurgov\u00e9 odstra\u0148uj\u00edc\u00ed rakovinov\u00e9 n\u00e1dory v oblasti hlavy a krku stoj\u00ed \u010dasto p\u0159ed t\u011b\u017ekou volbou, maj\u00ed d\u00e1t p\u0159ednost zachov\u00e1n\u00ed d\u016fle\u017eit\u00fdch org\u00e1n\u016f, jako jsou t\u0159eba hlasivky nebo hltan nebo bezpe\u010dn\u011b vy\u0159\u00edznout cel\u00fd n\u00e1dor i za cenu, \u017ee pacient si ponese do\u017eivotn\u00ed zdravotn\u00ed n\u00e1sledky. Pomoct v rozhodov\u00e1n\u00ed m\u016f\u017ee tzv. navigovan\u00e1 chirurgie, v r\u00e1mci kter\u00e9 vyv\u00edjej\u00ed \u010de\u0161t\u00ed v\u011bdci speci\u00e1ln\u00ed polymern\u00ed sondy, ty m\u016f\u017eou do budoucna ukazovat chirurg\u016fm p\u0159i operaci cestu.<\/p>\n\n\n\n
V po\u0159adu V\u011bda Plus v\u00edt\u00e1m Tom\u00e1\u0161e Etrycha, vedouc\u00edho odd\u011blen\u00ed biol\u00e9ka\u0159sk\u00fdch polymer\u016f z \u00dastavu makromolekul\u00e1rn\u00edch chemie Akademie v\u011bd, jeho\u017e t\u00fdm tento typ sondy vyv\u00edj\u00ed. Pane Etrychu, jak si ty polymern\u00ed sondy vlastn\u011b p\u0159edstavit, jak vypadaj\u00ed?<\/p>\n\n\n\n
mluv\u010d\u00ed 8,<\/strong> Takov\u00e9 mal\u00e9 objekty maj\u00ed, \u0159ekn\u011bme, velikosti v nanometrov\u00e9 \u0161k\u00e1le, to znamen\u00e1, \u017ee pro n\u00e1s jako pro \u010dlov\u011bka jsou neviditeln\u00e9, jsou velice mal\u00e9 a jsou dokonce velice mal\u00e9 i vzhledem t\u0159eba k jednotliv\u00fdm bu\u0148k\u00e1m na\u0161eho t\u011bla. <\/p>\n\n\n\n moder\u00e1tor<\/strong> A jak v t\u011ble pacienta p\u0159i operaci funguj\u00ed, pracuj\u00ed?<\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> My ty sondy vyv\u00edj\u00edme tak, aby dok\u00e1zaly naj\u00edt tu n\u00e1dorovou tk\u00e1\u0148 a v t\u00e9 n\u00e1dorov\u00e9 tk\u00e1ni se jakoby rozsv\u00edtili, to znamen\u00e1, \u017ee oni vlastn\u011b putuj\u00ed t\u011blem a putuj\u00ed v takov\u00e9m stavu, kdy jsou jakoby vypnut\u00e9, a ve chv\u00edli, kdy najdou tu n\u00e1dorovou tk\u00e1\u0148, tak se zapnou a vlastn\u011b cel\u00fd ten n\u00e1dor rozsv\u00edt\u00ed.<\/p>\n\n\n\n moder\u00e1tor<\/strong> No, a v sou\u010dasnosti tedy nemaj\u00ed chirurgov\u00e9 \u017e\u00e1dn\u00fd podobn\u00fd n\u00e1stroj, kter\u00fd by jim v rozhodov\u00e1n\u00ed pom\u00e1hal. <\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> No, maj\u00ed, \u0159ekn\u011bme, takov\u00e9 jednoduch\u00e9 mo\u017enosti, maj\u00ed…., vyu\u017e\u00edvaj\u00ed toho, \u017ee n\u011bkdy n\u00e1dorov\u00e1 tk\u00e1\u0148 tro\u0161inku jinak vypad\u00e1 v r\u00e1mci n\u011bjak\u00e9ho zobrazov\u00e1n\u00ed, tak\u017ee oni m\u016f\u017eou vid\u011bt, \u017ee ta n\u00e1dorov\u00e1 tk\u00e1\u0148 vypad\u00e1 malinkato jinak ne\u017e ta klasick\u00e1 tk\u00e1\u0148 a sna\u017e\u00ed se toho vyu\u017e\u00edt, ale tyto metody nejsou p\u0159\u00edli\u0161, \u0159ekn\u011bme, pe\u010dliv\u00e9 a \u010dasto ned\u00e1vaj\u00ed dostate\u010dnou informaci.<\/p>\n\n\n\n Ond\u0159ej L\u00e1tal, moder\u00e1tor<\/strong> A p\u0159edpokl\u00e1d\u00e1m, \u017ee to se bav\u00edme nap\u0159\u00edklad i o neurochirurgii.<\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> Ano, samoz\u0159ejm\u011b i u t\u00e9 neurochirurgie, ano.<\/p>\n\n\n\n Ond\u0159ej L\u00e1tal, moder\u00e1tor<\/strong> Jak se ty sondy do t\u011bla dopravuj\u00ed a jak dlouho tam p\u016fsob\u00ed. <\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> V p\u0159\u00edpad\u011b t\u011bch na\u0161ich sond? My p\u0159edpokl\u00e1d\u00e1me, \u017ee by se pod\u00e1valy p\u0159\u00edmo do \u017e\u00edly a \u0159ekn\u011bme, \u017ee by m\u011bli p\u016fsobit z\u0159ejm\u011b p\u0159ibli\u017en\u011b jeden den, co\u017e je tak akor\u00e1t doba, b\u011bhem kter\u00e9 by se mohla ud\u011blat pr\u00e1v\u011b ta pl\u00e1novan\u00e1 operace a mohlo by to pomoci t\u011bm chirurg\u016fm naj\u00edt ten n\u00e1dor a spr\u00e1vn\u011b ho odstranit.<\/p>\n\n\n\n Ond\u0159ej L\u00e1tal, moder\u00e1tor<\/strong> Mohly by se va\u0161e sondy hodit t\u0159eba na operace i jin\u00e9ho typu, a\u0165 u\u017e t\u0159eba jin\u00e9 \u010d\u00e1sti t\u011bla ne\u017e pr\u00e1v\u011b hlavy a krku, o kter\u00fdch jsme te\u010f mluvili, ale nebo t\u0159eba i jin\u00e9ho druhu onemocn\u011bn\u00ed. <\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> My si mysl\u00edme, \u017ee ano. A vlastn\u011b te\u010f za\u010d\u00edn\u00e1me tak\u00e9 spolupr\u00e1ci ohledn\u011b t\u0159eba metastatick\u00fdch lo\u017eisek, kter\u00e9 se nach\u00e1zej\u00ed v b\u0159i\u0161n\u00ed dutin\u011b, kde si tak\u00e9 mysl\u00edme, \u017ee by ty na\u0161e sondy mohly b\u00fdt pom\u011brn\u011b \u00fasp\u011b\u0161n\u00e9 v tom, jak by mohly jakoby zobrazit ty mal\u00e9 n\u00e1dory, kter\u00e9 se tam objevuj\u00ed, a mo\u017en\u00e1 tro\u0161ku hypoteticky by se dalo tak\u00e9 uva\u017eovat o tom, \u017ee bysme mohli takto zobrazovat t\u0159eba n\u011bjak\u00e9 z\u00e1n\u011btliv\u00e9 \u010d\u00e1sti organismu, pokud by to bylo pot\u0159eba.<\/p>\n\n\n\n Ond\u0159ej L\u00e1tal, moder\u00e1tor<\/strong> On ten v\u00e1\u0161 v\u00fdzkum je zat\u00edm, pokud m\u00e1m spr\u00e1vn\u00e9 informace, ve f\u00e1zi preklinick\u00fdch studi\u00ed, co to vlastn\u011b pro v\u00e1s znamen\u00e1, co je je\u0161t\u011b pot\u0159eba v t\u00e9to f\u00e1zi ov\u011b\u0159it?<\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> M\u00e1te pravdu, my vlastn\u011b v tuto chv\u00edli ty sondy vyv\u00edj\u00edme sp\u00ed\u0161e tak pro z\u00e1kladn\u00ed experimenty na zv\u00ed\u0159atech, to znamen\u00e1 na my\u0161k\u00e1ch, v p\u0159\u00edpad\u011b v\u011bt\u0161\u00edch zv\u00ed\u0159atech, a samoz\u0159ejm\u011b pokud bysme zjistili, \u017ee v\u0161echny ty sondy funguj\u00ed a nejsou toxick\u00e9 a daj\u00ed se pou\u017e\u00edt, tak bysme potom mohli p\u0159ej\u00edt vlastn\u011b k n\u011bjak\u00e9mu dal\u0161\u00edmu testov\u00e1n\u00ed na pacientech u\u017e jakoby lidsk\u00fdch.<\/p>\n\n\n\n Ond\u0159ej L\u00e1tal, moder\u00e1tor<\/strong> A pokud te\u010f, kdy\u017e se tedy koukneme hodn\u011b do budoucna, mo\u017en\u00e1, ale pokud by to testov\u00e1n\u00ed bylo i d\u00e1le \u00fasp\u011b\u0161n\u00e9? Za jak dlouho m\u00e1te p\u0159edpoklad, \u017ee by se tato technika mohla objevit na opera\u010dn\u00edch s\u00e1lech v nemocnic\u00edch? V praxi.<\/p>\n\n\n\n mluv\u010d\u00ed 8,<\/strong> Jo. D\u011bkuji za tu ot\u00e1zku. J\u00e1 bych byl nejrad\u0161i, kdyby to mohl b\u00fdt t\u0159eba i z\u00edtra, ale samoz\u0159ejm\u011b takto rychle to asi b\u00fdt nem\u016f\u017ee. J\u00e1 bych o\u010dek\u00e1val, \u017ee to m\u016f\u017ee b\u00fdt t\u0159eba v n\u011bjak\u00fdm horizontu n\u011bkolika let. <\/p>\n\n\n\n moder\u00e1tor<\/strong> Tom\u00e1\u0161 Erych, vedouc\u00ed odd\u011blen\u00ed biol\u00e9ka\u0159sk\u00fdch polymer\u016f, \u00dastav makromolekul\u00e1rn\u00ed chemie Akademie v\u011bd \u010cesk\u00e9 republiky, byl hostem v\u011bdy plus. D\u011bkuju v\u00e1m.<\/p>\n","protected":false},"excerpt":{"rendered":" Navigovan\u00e1 chirurgie pom\u00e1h\u00e1 l\u00e9ka\u0159\u016fm p\u0159esn\u011bji operovat n\u00e1dory v t\u011ble, \u010de\u0161t\u00ed v\u011bdci te\u010f vyv\u00edjej\u00ed speci\u00e1ln\u00ed naviga\u010dn\u00ed sondy v nano velikosti, kter\u00e9 dok\u00e1\u017eou okraje n\u00e1dor\u016f doslova rozsv\u00edtit. […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":58909,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-58743","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/58743","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=58743"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/58743\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/58909"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=58743"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=58743"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=58743"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}