Brn\u011bn\u0161t\u00ed chemici cht\u011bj\u00ed objasnit p\u016fvod nemoc\u00ed, jako jsou nap\u0159\u00edklad Parkinsonova nebo Alzheimerova choroba. T\u00fdm Tom\u00e1\u0161e Fialy z P\u0159\u00edrodov\u011bdeck\u00e9 fakulty Masarykovy univerzity zkoum\u00e1, jak se shluky b\u00edlkovin chovaj\u00ed v lidsk\u00e9m t\u011ble a jak jejich poruchy mohou v mozku spustit reakci, kter\u00e1 po\u0161kozuje nervov\u00e9 bu\u0148ky. V\u00fdzkum by jednou mohl p\u0159isp\u011bt k prevenci t\u011bchto onemocn\u011bn\u00ed. <\/p>\n\n\n\n
mluv\u010d\u00ed 5,<\/strong> Student chemie Mat\u011bj Osi\u010dka mi ukazuje parn\u00ed l\u00e1ze\u0148, ve kter\u00e9 se ot\u00e1\u010d\u00ed Ba\u0148ka s \u010dist\u00edc\u00ed se b\u00edlkovinou. <\/p>\n\n\n\n mluv\u010d\u00ed 4,<\/strong> Budeme pot\u0159ebovat odpa\u0159it rozpu\u0161t\u011bdlo, v kter\u00e9m to m\u00e1me, proto tady m\u00e1me rota\u010dn\u00ed vakovou odparku…<\/p>\n\n\n\n pro\u010d to vlastn\u011b odpa\u0159ujeme, abychom dostali ten n\u00e1\u0161 produkt na \u010distou l\u00e1tku? <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> My chceme zjistit, jakou funkci b\u00edlkoviny pro vznik t\u011bch neurodogenerativn\u00edch onemocn\u011bn\u00ed maj\u00ed. My se zam\u011b\u0159ujeme na ur\u010dit\u00e9 chemick\u00e9 zm\u011bny a chceme v podstat\u011b studovat, co tyhle ty zm\u011bny na t\u011bch b\u00edlkovin\u00e1ch d\u011blaj\u00ed z jejich funkc\u00ed a jak\u00fd to m\u00e1 potom vliv na tu nemoc samotnou<\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong> Dopl\u0148uje autor v\u00fdzkumu Tom\u00e1\u0161 Fiala z P\u0159\u00edrodov\u011bdeck\u00e9 fakulty Masarykovy univerzity. Ten vyv\u00edj\u00ed tzv. chemick\u00e9 sondy, kter\u00e9 dok\u00e1\u017e\u00ed b\u00edlkoviny zviditelnit a uk\u00e1zat, jak se chovaj\u00ed v r\u016fzn\u00fdch podm\u00ednk\u00e1ch. <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> N\u011bjak\u00e1 mal\u00e1 b\u00edlkovina,<\/strong> p\u0159ipom\u00edn\u00e1 kolagen, co\u017e je jedna z nejb\u011b\u017en\u011bj\u0161\u00edch b\u00edlkovin v lidsk\u00e9m t\u011ble, dopl\u0148uje student chemie Michal Jaro\u0161. <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> B\u00edl\u00fd pr\u00e1\u0161ek, tohle je jedna aminokyselina, tomeglycin. <\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong>Chemici kombinuj\u00ed celou \u0159adu t\u011bchto b\u00edlkovin a sleduj\u00ed, jak se chovaj\u00ed, d\u00edky tomu mohou zjistit, jestli ur\u010dit\u00e9 kombinace dok\u00e1\u017eou napodobit procesy, kter\u00e9 v mozku vedou k nemocem, jako je Parkinsonova nebo Alzheimerova choroba. <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> Podle t\u00e9 na\u0161\u00ed hypot\u00e9zy se m\u016f\u017eeme d\u00edvat na Alzheimerovu chorobu jako autoimunitn\u00ed, jako je t\u0159eba alergie, jsou taky autoimunitn\u00ed choroby, kdy vlastn\u011b n\u00e1\u0161 imunitn\u00ed syst\u00e9m p\u0159e\u017eene reakci na n\u011bjak\u00fd alergen, t\u0159eba pyl nebo prach <\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong> Podle Tom\u00e1\u0161e Fialy imunitn\u00ed syst\u00e9m reaguje p\u0159ehnan\u011b a za\u010dne \u0161kodit vlastn\u00edm bu\u0148k\u00e1m m\u00edsto toho, aby je chr\u00e1nil. <\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong>Chemici sm\u011b\u0159uj\u00ed ve sv\u00e9m v\u00fdzkumu k tomu, aby se t\u011bmto onemocn\u011bn\u00edm dalo v budoucnosti p\u0159edej\u00edt. <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> Kdy\u017e budeme v\u011bd\u011bt, \u017ee ur\u010dit\u00e1 chemick\u00e1 zm\u011bna na b\u00edlkovin\u011b vede k zbl\u00e1zn\u011bn\u00e9mu imunitn\u00edmu syst\u00e9mu, budeme schopni tuto reakci uti\u0161it. <\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong> Podle v\u011bdc\u016f by to mohla b\u00fdt kl\u00ed\u010dov\u00e1 stopa pro dal\u0161\u00ed v\u00fdzkum a mo\u017en\u00e1 i pro farmaceutick\u00e9 firmy, kter\u00e9 by jednou mohly vyv\u00edjet l\u00e9ky na zklidn\u011bn\u00ed imunitn\u00edch reakc\u00ed v mozku. <\/p>\n\n\n\n mluv\u010d\u00ed 6,<\/strong> Zji\u0161\u0165ujeme mo\u017en\u00e9 p\u0159\u00ed\u010diny. Vyvinout proti nim protipo\u017e\u00e1rn\u00ed opat\u0159en\u00ed. <\/p>\n\n\n\n mluv\u010d\u00ed 5,<\/strong> \u0158\u00edk\u00e1 chemik Tom\u00e1\u0161 Fiala, kter\u00fd na v\u00fdzkum neurodegenerativn\u00edch onemocn\u011bn\u00ed z\u00edskal n\u011bkolik v\u00fdznamn\u00fdch grant\u016f a nyn\u00ed buduje na Masarykov\u011b univerzit\u011b vlastn\u00ed laborato\u0159 se \u0161pi\u010dkov\u00fdm t\u00fdmem v\u011bdc\u016f z cel\u00e9ho sv\u011bta. <\/p>\n\n\n\n \u010cesk\u00fd rozhlas<\/p>\n\n\n\n <\/p>\n","protected":false},"excerpt":{"rendered":" Brn\u011bn\u0161t\u00ed chemici cht\u011bj\u00ed objasnit p\u016fvod nemoc\u00ed, jako jsou nap\u0159\u00edklad Parkinsonova nebo Alzheimerova choroba. T\u00fdm Tom\u00e1\u0161e Fialy z P\u0159\u00edrodov\u011bdeck\u00e9 fakulty Masarykovy univerzity zkoum\u00e1, jak se shluky […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":14161,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-62080","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zpravy"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/62080","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=62080"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/62080\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/14161"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=62080"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=62080"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=62080"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}