Miln\u00edk v genetick\u00fdch \u00faprav\u00e1ch lidsk\u00fdch embry\u00ed. T\u00fdm pod veden\u00edm \u010desk\u00e9ho v\u011bdce \u0160t\u011bp\u00e1na Je\u0159\u00e1bka dok\u00e1zal d\u011bdi\u010dnou informaci zm\u011bnit mnohem \u0161etrn\u011bji, a nav\u00edc velmi p\u0159esn\u011b. To m\u016f\u017ee v budoucnu znamenat pomoc t\u0159eba u rodin s d\u011bdi\u010dn\u00fdm genetick\u00fdm onemocn\u011bn\u00edm. Studii zve\u0159ejnil \u010dasopis Nature.<\/p>\n\n\n\n
\u010cT<\/p>\n\n\n\n
Model p\u00e1r dn\u016f star\u00e9ho embrya. V podobn\u00e9m st\u00e1diu je kliniky um\u011bl\u00e9ho oplodn\u011bn\u00ed vlo\u017e\u00ed do d\u011blohy a v\u011bdci kolem \u0160t\u011bp\u00e1na Je\u0159\u00e1bka je \u00fasp\u011b\u0161n\u011b upravili. Ze \u0161esti miliard p\u00edsmen lidsk\u00e9 DNA um\u00ed zm\u011bnit t\u0159eba jenom jedno jedin\u00e9.<\/p>\n\n\n\n
\u0160t\u011bp\u00e1n Je\u0159\u00e1bek,Kolumbijsk\u00e1 univerzita, \u00daOCHB AV \u010cR<\/p>\n\n\n\n
Proto vlastn\u011b ta metoda je \u0161etrn\u011bj\u0161\u00ed, nedoch\u00e1z\u00ed k p\u0159eru\u0161en\u00ed t\u00e9 dvojvl\u00e1knov\u00e9 DNA.<\/p>\n\n\n\n
Jaroslav Zoula,redaktor \u010cT<\/p>\n\n\n\n
Kv\u016fli voln\u011bj\u0161\u00edm pravidl\u016fm v\u00fdzkum prob\u00edh\u00e1 ve Spojen\u00fdch st\u00e1tech. \u010cesk\u00e1 stopa se ale neomezila jen na \u0160t\u011bp\u00e1na Je\u0159\u00e1bka. D\u016fle\u017eitou roli v tomto v\u00fdzkumu hr\u00e1li i v\u011bdci z pra\u017esk\u00e9ho \u00dastavu organick\u00e9 chemie a biochemie, konkr\u00e9tn\u011b p\u0159ipravovali chemik\u00e1lie, kter\u00e9 n\u011bkter\u00e9 z t\u011bchto genetick\u00fdch zm\u011bn prov\u00e1d\u011bly.<\/p>\n\n\n\n
Michal Dole\u017eal,\u00dastav organick\u00e9 chemie a biochemie AV \u010cR<\/p>\n\n\n\n
Tento nov\u00fd n\u00e1stroj, ten vlastn\u011b pom\u00e1h\u00e1 k tomu, aby se embryo p\u0159irozen\u011bji vyv\u00edjelo.<\/p>\n\n\n\n
00:01:00<\/p>\n\n\n\n
Jaroslav Zoula,redaktor \u010cT<\/p>\n\n\n\n
A u novorozence by \u00fapravy sn\u00ed\u017eily riziko infarktu a dvou d\u011bdi\u010dn\u00fdch chorob, ale v\u011bdci v\u00fdvoj embrya podle platn\u00fdch pravidel po \u0161esti dnech zastavili. Z\u00edskali ho od d\u00e1rky\u0148, kter\u00e9 podstupovaly um\u011bl\u00e9 oplodn\u011bn\u00ed a nevyu\u017eil je. Pr\u00e1v\u011b p\u0159i IVF by podobn\u00e1 metoda mohla v budoucnu pomoct.<\/p>\n\n\n\n
00:01:18<\/p>\n\n\n\n
\u0160t\u011bp\u00e1n Je\u0159\u00e1bek,Kolumbijsk\u00e1 univerzita, \u00daOCHB AV \u010cR<\/p>\n\n\n\n
Pokud by existovala technologie bezpe\u010dn\u00e1 pro tu \u00fapravu t\u011bch gen\u016f, tak m\u016f\u017eeme vyu\u017e\u00edt tu na\u0161i metodu k tomu, \u017ee bychom opravili ten gen a zv\u00fd\u0161ili po\u010det vlastn\u011b implantovateln\u00fdch embry\u00ed pro ty rodi\u010de.<\/p>\n\n\n\n
00:01:30<\/p>\n\n\n\n
Jaroslav Zoula,redaktor \u010cT<\/p>\n\n\n\n
I kdy\u017e v\u011bdci uji\u0161\u0165uj\u00ed, \u017ee jde jen o experimenty, vyvol\u00e1vaj\u00ed spory. Mimo jin\u00e9 i proto, \u017ee tyto postupy cht\u011bj\u00ed v budoucnu nab\u00edzet soukrom\u00e9 firmy.<\/p>\n\n\n\n
V\u011bra Frankov\u00e1,\u00dastav l\u00e9ka\u0159sk\u00e9 biochemie a laboratorn\u00ed diagnostiky 1. LF UK<\/p>\n\n\n\n
Douf\u00e1m, \u017ee v sou\u010dasn\u00e9 dob\u011b je\u0161t\u011b nep\u016fjde tento v\u00fdzkum do praxe, \u017ee bude ta bezpe\u010dnost je\u0161t\u011b d\u00e1le vlastn\u011b zkoum\u00e1na.<\/p>\n\n\n\n
00:01:46<\/p>\n\n\n\n
Jaroslav Zoula,redaktor \u010cT<\/p>\n\n\n\n
Co\u017e v\u011bdci potvrzuj\u00ed. Hlavn\u00ed obavou je, \u017ee d\u00edt\u011b narozen\u00e9 s upraven\u00e9ho embrya p\u0159enese z\u00e1sahy na dal\u0161\u00ed generaci. Zbavit dosp\u011bl\u00e9 onemocn\u011bn\u00ed pomoc\u00ed genetick\u00fdch \u00faprav se v\u011bdc\u016fm da\u0159\u00ed u\u017e te\u010f. <\/p>\n\n\n\n
\u010cesk\u00e1 televize.<\/p>\n","protected":false},"excerpt":{"rendered":"
Miln\u00edk v genetick\u00fdch \u00faprav\u00e1ch lidsk\u00fdch embry\u00ed. T\u00fdm pod veden\u00edm \u010desk\u00e9ho v\u011bdce \u0160t\u011bp\u00e1na Je\u0159\u00e1bka dok\u00e1zal d\u011bdi\u010dnou informaci zm\u011bnit mnohem \u0161etrn\u011bji, a nav\u00edc velmi p\u0159esn\u011b. To m\u016f\u017ee […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":27890,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-64959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/64959","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=64959"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/64959\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/media\/27890"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=64959"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=64959"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=64959"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}