<\/p>\n
Ta nemoc se doposud nedala l\u00e9\u010dit: postupn\u00e9 ochrnov\u00e1n\u00ed v\u0161ech sval\u016f v t\u011ble a\u017e do doby, dokud \u010dlov\u011bk nezem\u0159e hlady a udu\u0161en\u00edm, proto\u017ee nem\u016f\u017ee ani polykat, ani d\u00fdchat. Jmenuje se amyotrofick\u00e1 later\u00e1ln\u00ed skler\u00f3za a pat\u0159\u00ed k nejstra\u0161n\u011bj\u0161\u00edm na sv\u011bt\u011b, proto\u017ee postupuje tak rychle, \u017ee pacient zem\u0159e obvykle b\u011bhem dvou t\u0159\u00ed let.<\/p>\n
Te\u010f m\u00e1 \u010cesko v\u00fdsledky klinick\u00fdch test\u016f u prvn\u00edch deseti pacient\u016f l\u00e9\u010den\u00fdch vlastn\u00edmi kmenov\u00fdmi bu\u0148kami. A zd\u00e1 se, \u017ee nemoc se poda\u0159ilo zpomalit podobn\u011b, jako se to uk\u00e1zalo p\u0159edt\u00edm na zv\u00ed\u0159atech.<\/p>\n
„Po\u0159\u00e1d jsme v prvn\u00ed f\u00e1zi test\u016f, kdy m\u00e1me hlavn\u011b prok\u00e1zat, \u017ee to je pro \u010dlov\u011bka bezpe\u010dn\u00e9. Tak\u017ee nem\u016f\u017eeme zodpov\u011bdn\u011b \u0159\u00edct, nakolik se choroba zpomalila, ale z prvn\u00edch reakc\u00ed pacient\u016f se zd\u00e1, \u017ee to bude podobn\u00e9 jako u zv\u00ed\u0159at,“ \u0159\u00edk\u00e1 exkluzivn\u011b pro MF DNES Eva Sykov\u00e1, \u0159editelka \u00dastavu experiment\u00e1ln\u00ed medic\u00edny Akademie v\u011bd. A zv\u00ed\u0159at\u016fm se stejnou nemoc\u00ed se povedlo prodlou\u017eit \u017eivot o p\u011btinu. Co\u017e je u t\u00e9to nemoci \u00fasp\u011bch.<\/p>\n
Kmenov\u00e9 bu\u0148ky vyzkou\u0161eli v Akademii v\u011bd na prvn\u00edch 42 pacientech p\u0159esn\u011b p\u0159ed deseti lety. Od t\u00e9 doby se z pouh\u00e9 nad\u011bje stala v n\u011bkter\u00fdch p\u0159\u00edpadech u\u017e skute\u010dn\u00e1 l\u00e9\u010dba, u dal\u0161\u00edch nemoc\u00ed pr\u00e1v\u011b b\u011b\u017e\u00ed testy na pacientech. A vypadaj\u00ed nad\u011bjn\u011b.<\/p>\n
Eva Sykov\u00e1 z \u00dastavu experiment\u00e1ln\u00ed medic\u00edny Akademie v\u011bd proto kmenov\u00fdm bu\u0148k\u00e1m v\u011b\u0159\u00ed coby l\u00e9\u010db\u011b budoucnosti.<\/p>\n
– Pan\u00ed profesorko, pro\u010d se vlastn\u011b v\u00fdzkum od po\u010d\u00e1tku ub\u00edr\u00e1 hlavn\u011b sm\u011brem k „opravov\u00e1n\u00ed“ nerv\u016f?<\/strong><\/p>\n Jednak se neurov\u011bdami cel\u00fd \u017eivot zab\u00fdv\u00e1m a pak proto, \u017ee \u00farazy mozku a m\u00edchy jsou obt\u00ed\u017en\u011b l\u00e9\u010diteln\u00e9 nebo v\u011bt\u0161inou nel\u00e9\u010diteln\u00e9. A jedin\u011b bun\u011b\u010dn\u00e1 terapie d\u00e1vala nad\u011bji, \u017ee by se mohla st\u00e1t l\u00e9kem. Proto se tak\u00e9 i ty prvn\u00ed klinick\u00e9 studie, z roku 2003, t\u00fdkaly pacient\u016f s p\u0159eru\u0161enou m\u00edchou. Na nich se tehdy prok\u00e1zala bezpe\u010dnost l\u00e9\u010dby.<\/p>\n – Co bylo pak?<\/strong><\/p>\n P\u0159i\u0161ly pokusy na zv\u00ed\u0159atech s geny um\u011ble pozm\u011bn\u011bn\u00fdmi tak, aby onemocn\u011bla amyotrofickou later\u00e1ln\u00ed skler\u00f3zou (smrteln\u00e9 nervov\u00e9 onemocn\u011bn\u00ed \u2013 pozn. red.). A mnohokr\u00e1t se poda\u0159ilo dok\u00e1zat, \u017ee kmenov\u00e9 bu\u0148ky vedou ke zpomalen\u00ed choroby. Testy jsme d\u011blali na potkanech a jejich p\u0159e\u017eit\u00ed se prodlou\u017eilo o dvacet procent, co\u017e je vzhledem k dvoulet\u00e9mu \u017eivotu laboratorn\u00edho potkana dost. Proto jsme loni po z\u00edskan\u00ed v\u0161ech pot\u0159ebn\u00fdch povolen\u00ed za\u010dali s klinickou studi\u00ed i u stejn\u011b nemocn\u00fdch lid\u00ed.<\/p>\n – A v\u00fdsledek?<\/strong><\/p>\n To budeme moci opravdu p\u0159esn\u011b \u0159\u00edct a\u017e po del\u0161\u00ed dob\u011b. Probl\u00e9m je v tom, \u017ee my ty pacienty mus\u00edme sledovat u\u017e p\u016fl roku p\u0159edt\u00edm, abychom zjistili, jak rychl\u00fd pr\u016fb\u011bh nemoc m\u00e1, abychom pak mohli \u0159\u00edct, nakolik se n\u00e1m ji poda\u0159ilo zpomalit. A nemoc prob\u00edh\u00e1 u ka\u017ed\u00e9ho \u010dlov\u011bka jinak. U n\u011bkoho velmi rychle, n\u011bkdo m\u00e1 pomalej\u0161\u00ed formu. A druh\u00e1 v\u011bc: jsme ve f\u00e1zi, kdy to zhodnocen\u00ed pacient\u016f mus\u00ed prob\u00edhat je\u0161t\u011b aspo\u0148 rok. L\u00e9ka\u0159i v motolsk\u00e9 nemocnici je sleduj\u00ed a je\u0161t\u011b chv\u00edli to potrv\u00e1, abychom mohli \u0159\u00edct skute\u010dn\u011b zodpov\u011bdn\u00e9 v\u00fdsledky.<\/p>\n – Podle \u010deho jste si ty pacienty vyb\u00edrali? P\u0159edpokl\u00e1d\u00e1m, \u017ee jste pro n\u011b byli posledn\u00ed nad\u011bj\u00ed…<\/strong><\/p>\n Ano a bylo to t\u011b\u017ek\u00e9. Ka\u017ed\u00e1 klinick\u00e1 studie m\u00e1 sv\u00e1 krit\u00e9ria, koho do n\u00ed sm\u00edme zahrnout. V tomto p\u0159\u00edpad\u011b nesm\u011bli b\u00fdt lid\u00e9 v posledn\u00edm stadiu choroby, proto\u017ee bychom je nemohli dostate\u010dn\u011b dlouho p\u0159edt\u00edm sledovat. Tak\u00e9 museli m\u00edt je\u0161t\u011b dobrou dechovou kapacitu a nesm\u011bli b\u00fdt star\u0161\u00ed 65 let. – Jak to pak cel\u00e9 prob\u00edhalo? Odebrali jsme pacient\u016fm vzorky kostn\u00ed d\u0159en\u011b, ty jsme p\u0159evezli na Akademii v\u011bd do na\u0161\u00ed firmy BioInova, kter\u00e1 m\u00e1 povolen\u00ed vyr\u00e1b\u011bt kmenov\u00e9 bu\u0148ky a m\u00e1 na to speci\u00e1ln\u00ed \u010dist\u00e9 prostory. Tady pak bu\u0148ky kultivujeme. Z\u016fstanou tu t\u0159i t\u00fddny a za tu dobu se mno\u017e\u00ed a vyselektuje se z nich speci\u00e1ln\u00ed typ bun\u011bk, kter\u00e9 se pak lumb\u00e1ln\u00ed punkc\u00ed vr\u00e1t\u00ed pacientovi do t\u011bla.<\/p>\n – Jen jednou? To sta\u010d\u00ed?<\/strong><\/p>\n V t\u00e9to studii m\u00e1me povolen\u00ed na jednor\u00e1zov\u00e9 pod\u00e1n\u00ed. Ta schvalov\u00e1n\u00ed l\u00e9kov\u00e9ho \u00fastavu jsou toti\u017e velmi obez\u0159etn\u00e1, aby pro pacienta nevznikla pokud mo\u017eno \u017e\u00e1dn\u00e1 rizika. Jen\u017ee u\u017e te\u010f se poda\u0159ilo prok\u00e1zat, \u017ee tam \u017e\u00e1dn\u00e9 komplikace nejsou, tak\u017ee uva\u017eujeme o tom, \u017ee bychom studii roz\u0161\u00ed\u0159ili na opakovan\u00e9 pod\u00e1n\u00ed bun\u011bk. A zd\u00e1 se, \u017ee se to poda\u0159\u00ed.<\/p>\n – Co se vlastn\u011b v t\u011ble pacienta d\u011bje pot\u00e9, co dostane l\u00e9\u010debnou d\u00e1vku sv\u00fdch kmenov\u00fdch bun\u011bk?<\/strong><\/p>\n Je pot\u0159eba si uv\u011bdomit, \u017ee ty bu\u0148ky v t\u011ble nenahrad\u00ed ty chyb\u011bj\u00edc\u00ed, ale zabr\u00e1n\u00ed tomu, aby do\u0161lo k jejich dal\u0161\u00ed rychl\u00e9 ztr\u00e1t\u011b. Zkr\u00e1tka zpomal\u00ed nemoc. Kdybychom je podali opakovan\u011b, dos\u00e1hli bychom je\u0161t\u011b lep\u0161\u00edho \u00fa\u010dinku. V pokusech na zv\u00ed\u0159atech se u\u017e prok\u00e1zalo, \u017ee efekt trv\u00e1 po celou dobu, co kmenov\u00e9 bu\u0148ky v t\u011ble \u017eij\u00ed. Ony funguj\u00ed vlastn\u011b jako takov\u00e9 mal\u00e9 tov\u00e1rny, kter\u00e9 vyr\u00e1b\u011bj\u00ed l\u00e1tky zabra\u0148uj\u00edc\u00ed degeneraci. Jenom\u017ee vydr\u017e\u00ed jen n\u011bkolik m\u011bs\u00edc\u016f. I proto si mysl\u00edm, \u017ee efekt l\u00e9\u010dby by byl lep\u0161\u00ed po dal\u0161\u00ed d\u00e1vce. Ide\u00e1ln\u011b t\u0159i d\u00e1vky po \u010dtvrt roce.<\/p>\n – Jen\u017ee kolik by to pak st\u00e1lo?<\/strong><\/p>\n Ano, to je probl\u00e9m. V\u00fdroba kmenov\u00fdch bun\u011bk je toti\u017e velmi drah\u00e1. Jedna d\u00e1vka pro pacienta stoj\u00ed 150 tis\u00edc korun. A to na tom na\u0161e spole\u010dnost nijak nevyd\u011bl\u00e1v\u00e1. Tak\u017ee opakov\u00e1n\u00ed je probl\u00e9m. Hled\u00e1me proto sponzory a granty, z nich\u017e je to mo\u017en\u00e9 financovat. M\u00e1me na to i nadaci Bun\u011b\u010dn\u00e1 terapie.<\/p>\n – U jak\u00fdch dal\u0161\u00edch nemoc\u00ed mohou kmenov\u00e9 bu\u0148ky pomoci?<\/strong><\/p>\n M\u00e1me te\u010f schv\u00e1lenou dal\u0161\u00ed klinickou studii na klouby, konkr\u00e9tn\u011b pro artr\u00f3zu ky\u010deln\u00edho kloubu a kolena. U\u017e jsme to zkusili u n\u011bkolika prvn\u00edch pacient\u016f. Taky m\u00e1me schv\u00e1lenou studii pro l\u00e9\u010dbu \u0161lach. Tady jde t\u0159eba o nemoc s n\u00e1zvem „rot\u00e1torov\u00e1 man\u017eeta“. A pro\u010d \u0161lachy? Proto\u017ee \u0161lachov\u00e1 onemocn\u011bn\u00ed se hoj\u00ed pomalu, bolav\u011b a hlavn\u011b: p\u0159i jak\u00e9koliv n\u00e1maze m\u016f\u017ee znovu doj\u00edt k po\u0161kozen\u00ed. A my m\u00e1me ov\u011b\u0159eno u kon\u00ed \u010di ps\u016f, kter\u00e9 u\u017e del\u0161\u00ed dobu l\u00e9\u010d\u00edme a s dobr\u00fdmi v\u00fdsledky, \u017ee to funguje a \u017ee se zran\u011bn\u00ed hoj\u00ed rychleji a l\u00e9pe. A b\u011b\u017e\u00ed i l\u00e9\u010dba diabetick\u00e9 nohy. Tady u\u017e m\u00e1me taky n\u011bkolik pacient\u016f, kde doch\u00e1z\u00ed ke zhojen\u00ed ran, je\u017e se jinak nezahojily a pacienti by museli podstoupit amputaci. Tam m\u00e1me pades\u00e1tiprocentn\u00ed \u00fasp\u011b\u0161nost, co\u017e je mysl\u00edm pro tuto nemoc l\u00e9\u010dba budoucnosti.<\/p>\n <\/p>\n Klinick\u00e9 testy, kter\u00e9 s kmenov\u00fdmi bu\u0148kami u pacient\u016f d\u011bl\u00e1 \u00fastav Evy Sykov\u00e9 jako jedin\u00fd u n\u00e1s, trvaj\u00ed rok. A je\u0161t\u011b n\u011bkolik m\u011bs\u00edc\u016f bude nutn\u00e9 pacienty sledovat a vyhodnocovat pr\u016fb\u011bh nemoci. P\u0159esto u\u017e te\u010f to znamen\u00e1, \u017ee z nad\u011bje a\u017e stovek \u010desk\u00fdch pacient\u016f se st\u00e1v\u00e1 skute\u010dnost. <\/strong><\/p>\n \u00dastav u\u017e m\u00e1 ostatn\u011b schv\u00e1leny dal\u0161\u00ed klinick\u00e9 testy: pr\u00e1v\u011b se rozb\u00edh\u00e1 l\u00e9\u010dba artr\u00f3zy kolena a ky\u010dle, chyst\u00e1 se l\u00e9\u010dba \u0161lach a u\u017e se l\u00e9\u010d\u00ed asi t\u0159ic\u00edtka pacient\u016f s tzv. diabetickou nohou, tedy nezahojiteln\u00fdmi ranami, kter\u00e9 kon\u010d\u00ed amputac\u00ed.<\/strong><\/p>\n „Tady m\u00e1me \u00fasp\u011b\u0161nost pades\u00e1tiprocentn\u00ed, co\u017e je velmi dobr\u00fd v\u00fdsledek,“ komentuje to Eva Sykov\u00e1.<\/p>\n To znamen\u00e1, \u017ee polovin\u011b pacient\u016f jinak beznad\u011bjn\u011b odsouzen\u00fdch ke ztr\u00e1t\u011b kon\u010detiny se r\u00e1ny zahojily.<\/p>\n \u00dasp\u011bch se tak trochu o\u010dek\u00e1val, proto\u017ee kmenov\u00e9 bu\u0148ky odeb\u00edran\u00e9 z kostn\u00ed d\u0159en\u011b u\u017e u n\u00e1s l\u00e9\u010d\u00ed zv\u00ed\u0159ata, nap\u0159\u00edklad kon\u011b a psy se zlomeninami, s natr\u017een\u00fdmi \u0161lachami nebo artr\u00f3zou. Tam je \u00fasp\u011b\u0161nost a\u017e sedmdes\u00e1tiprocentn\u00ed.<\/p>\n V\u0161echno nasv\u011bd\u010duje tomu, \u017ee u nemoc\u00ed kloub\u016f, \u0161lach, po\u0161kozen\u00e9 m\u00edchy, ale i p\u0159i kosmetick\u00fdch operac\u00edch budou tyto bu\u0148ky brzy nepostradateln\u00e9. I u oby\u010dejn\u00fdch operac\u00ed toti\u017e napom\u00e1haj\u00ed rychlej\u0161\u00edmu hojen\u00ed. Jinde, u chrupavek \u010di nervov\u00fdch bun\u011bk, zase um\u011bj\u00ed „opravit“, tedy zacelit po\u0161kozenou \u010d\u00e1st.<\/p>\n V\u0161eobecn\u00e1 zdravotn\u00ed poji\u0161\u0165ovna u\u017e loni za\u010dala propl\u00e1cet l\u00e9\u010dbu kolenn\u00edch chrupavek za pomoci takov\u00e9 bun\u011b\u010dn\u00e9 terapie. „V roce 2012 jsme nasmlouvali 100 takov\u00fdch v\u00fdkon\u016f ve t\u0159ech nemocnic\u00edch a pro leto\u0161ek to je ji\u017e jednou tolik v\u00fdkon\u016f v dev\u00edti nemocnic\u00edch,“ \u0159\u00edk\u00e1 mluv\u010d\u00ed VZP Old\u0159ich Tich\u00fd.<\/p>\n Zat\u00edmco u v\u00e1\u017en\u00fdch nemoc\u00ed, jako je pr\u00e1v\u011b smrteln\u00e9 postupn\u00e9 ochrnut\u00ed sval\u016f, \u010di t\u0159eba u m\u00ed\u0161n\u00edch l\u00e9z\u00ed, co\u017e je poran\u011bn\u00ed m\u00edchy po \u00farazu vedouc\u00ed k ochrnut\u00ed \u010dlov\u011bka, si na l\u00e9\u010dbu a jej\u00ed p\u0159\u00edpadn\u00e9 propl\u00e1cen\u00ed od poji\u0161\u0165oven mus\u00ed pacienti je\u0161t\u011b po\u010dkat, a\u017e jak dopadnou klinick\u00e9 zkou\u0161ky. Zat\u00edm l\u00e9\u010dbu plat\u00ed nadace a granty Akademie v\u011bd, n\u011bco si u\u017e te\u010f mohou lid\u00e9 zaplatit sami.<\/p>\n L\u00e9\u010d\u00ed se i vlastn\u00edm tukem<\/strong><\/p>\n N\u011bkter\u00e9 kliniky plastick\u00fdch chirurgi\u00ed t\u0159eba nab\u00edzej\u00ed vyu\u017eit\u00ed tuku z t\u011bla, co\u017e je vedle kostn\u00ed d\u0159en\u011b dal\u0161\u00ed v\u00fdznamn\u00fd zdroj kmenov\u00fdch bun\u011bk. A t\u0159eba p\u0159i operac\u00edch prs\u016f pom\u00e1h\u00e1 lep\u0161\u00edmu hojen\u00ed. Podporuje toti\u017e regeneraci bun\u011bk.<\/p>\n „Pr\u00e1v\u011b se rozb\u00edh\u00e1 na\u0161e spolupr\u00e1ce s n\u011bkolika klinikami, kdy pro n\u011b budeme kmenov\u00e9 bu\u0148ky odebran\u00e9 pacient\u016fm vyr\u00e1b\u011bt,“ popsala Eva Sykov\u00e1.<\/p>\n Vznik\u00e1 tak sedm odb\u011brov\u00fdch m\u00edst, kde se pacienti budou moci nechat operovat a pomoci si p\u0159itom k lep\u0161\u00edmu v\u00fdsledku vlastn\u00edmi kmenov\u00fdmi bu\u0148kami.<\/p>\n „Ty nemocnice jsou Motol, Asklepion, Malvazinky, v Praze Na Franti\u0161ku, \u010cesk\u00e9 Bud\u011bjovice, l\u00e1zn\u011b Teplice a snad i Vinohrady,“ vyjmenov\u00e1v\u00e1 Karel Havl\u00ed\u010dek z holdingu Sindat, co\u017e je uskupen\u00ed biotechnologick\u00fdch firem, kter\u00e9 spoluvlastn\u00ed firmu Akademie v\u011bd. „P\u0159edpokl\u00e1d\u00e1me, \u017ee to budou pacienti vyu\u017e\u00edvat hlavn\u011b u ortopedick\u00fdch z\u00e1krok\u016f nebo p\u0159i kosmetick\u00fdch operac\u00edch,“ dod\u00e1v\u00e1.<\/p>\n Cena za odb\u011br, \u00fapravu a zp\u011btn\u00e9 vr\u00e1cen\u00ed bun\u011bk do t\u011bla pacienta p\u0159ijde i s pobytem v nemocnici na zhruba 25 a\u017e 50 tis\u00edc korun.<\/p>\n U klinick\u00fdch test\u016f, kde ji za\u0159azen\u00fdm pacient\u016fm plat\u00ed Akademie v\u011bd a kde jde o kultivovan\u00e9 kmenov\u00e9 bu\u0148ky, je to 150 tis\u00edc za jednu l\u00e9\u010debnou d\u00e1vku.<\/p>\n A jak je mo\u017en\u00e9, \u017ee pom\u00e1haj\u00ed jak bu\u0148ky z tukov\u00e9 tk\u00e1n\u011b, tak ty z kostn\u00ed d\u0159en\u011b? A kter\u00e9 jsou lep\u0161\u00ed?<\/p>\n „Z\u00e1le\u017e\u00ed na druhu nemoci,“ \u0159\u00edk\u00e1 Eva Sykov\u00e1. „Pro ur\u010dit\u00e1 onemocn\u011bn\u00ed jsou lep\u0161\u00ed ty z kostn\u00ed d\u0159en\u011b \u2013 jsou sv\u00fdm uzp\u016fsoben\u00edm bl\u00ed\u017ee nervov\u00fdm bu\u0148k\u00e1m, tak\u017ee na po\u0161kozenou m\u00edchu, pro artr\u00f3zy, hojen\u00ed \u0161lach a hlavn\u011b pro nohy diabetik\u016f jsou vhodn\u011bj\u0161\u00ed tyto. Pro kosmetick\u00e9 operace zase ty druh\u00e9,“ vysv\u011btluje Sykov\u00e1.<\/p>\n Kmenov\u00e9 bu\u0148ky ur\u010dit\u011b neum\u011bj\u00ed l\u00e9\u010dit v\u0161echno, ale u \u0159ady nemoc\u00ed um\u00ed „nakopnout“ t\u011blo, aby si pomohlo samo.<\/p>\n <\/p>\n Mlad\u00e1 fronta Dnes<\/p>\n Lenka Petr\u00e1\u0161ov\u00e1<\/p>\n","protected":false},"excerpt":{"rendered":" Postupn\u011b ochrnou a udus\u00ed se. \u00dasp\u011bch \u010desk\u00fdch v\u011bdc\u016f jim v\u0161ak d\u00e1 \u0161anci \u017e\u00edt. Testuj\u00ed prvn\u00ed l\u00e9ky s kmenov\u00fdmi bu\u0148kami a u prvn\u00edch pacient\u016f s nel\u00e9\u010ditelnou […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-6882","post","type-post","status-publish","format-standard","hentry","category-zdravi"],"_links":{"self":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/6882","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6882"}],"version-history":[{"count":0,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=\/wp\/v2\/posts\/6882\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6882"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6882"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.invarena.cz\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6882"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}